Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jess McKenzie"'
Autor:
Michael J. Adam, Jessie Fanglu Fu, Mariya V. Cherkasova, Jason Valerio, Elham Shahinfard, Jing Zhang, Shu-Ying Liu, Siobhan McCormick, Nasim Vafai, Daryl Wile, Martin J. McKeown, Thomas J. Ruth, Vesna Sossi, Zbigniew K. Wszolek, Julieta E. Arena, Alexandra Perez-Soriano, Rostom Mabrouk, Cyrus P. Zabetian, Nicole Neilson, Jess McKenzie, Jan O. Aasly, Michael Schulzer, Piu Chan, A. Jon Stoessl
Publikováno v:
The Lancet. Neurology. 17(4)
Summary Background Markers of neuroinflammation are increased in some patients with LRRK2 Parkinson's disease compared with individuals with idiopathic Parkinson's disease, suggesting possible differences in disease pathogenesis. Previous PET studies
Autor:
Martin J. McKeown, Nasim Vafai, Silke Appel-Cresswell, Jess McKenzie, Marjorie Gonzalez, Nicole Heffernan, Vesna Sossi, A. Jon Stoessl, Katherine Dinelle
Publikováno v:
NeuroImage. 68:11-21
We present a novel analysis method for positron emission tomography (PET) data that uses the spatial characteristics of the radiotracer's distribution within anatomically-defined regions of interest (ROIs) to provide an independent feature that may a
Autor:
Donald B. Calne, A. Jon Stoessl, Lisa Kuramoto, Raúl de la Fuente-Fernández, Chong S. Lee, Siobhan McCormick, Jacquelyn J. Cragg, Wing Lok Au, Edwin Mak, Vesna Sossi, Jess McKenzie, Michael Schulzer, Thomas J. Ruth, Nandhagopal Ramachandiran
Publikováno v:
Annals of Neurology. 69:803-810
Objective: To investigate in vivo the impact of age on nigrostriatal dopamine dysfunction in Parkinson's disease (PD). Methods: PD patients (n = 78) and healthy control subjects (n = 35) underwent longitudinal positron emission tomography assessments
Autor:
Siobhan McCormick, Jacqueline Cragg, R. Nandhagopal, Vesna Sossi, Lisa Kuramoto, Raúl de la Fuente-Fernández, A. Jon Stoessl, Edwin Mak, Jess McKenzie, Michael Schulzer, Thomas J. Ruth
Publikováno v:
Brain : a journal of neurology. 134(Pt 11)
Parkinson's disease is a relentlessly progressive neurodegenerative disease. Breakdown of compensatory mechanisms influencing putaminal dopamine processing could contribute to the progressive motor symptoms. We studied a cohort of 78 subjects (at bas
Autor:
Thomas J. Ruth, Vesna Sossi, Raúl de la Fuente-Fernández, André R. Troiano, Jess McKenzie, Michael Schulzer, A. Jon Stoessl, Siobhan McCormick, Edwin Mak
Publikováno v:
Synapse (New York, N.Y.). 64(2)
Objectives: To determine the impact of age-related decline in dopamine transporter (DAT) expression on motor function in the elderly. Methods: About 33 normal individuals of a wide age range were scanned with PET employing d-threo-[11C]-methylphenida
Autor:
Thomas J. Ruth, Jess McKenzie, Doris J. Doudet, Raúl de la Fuente-Fernández, A. J. Stoessl, James E. Holden, Vesna Sossi
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 22(2)
An increase in dopamine turnover has been hypothesized to occur early in Parkinson's disease (PD) as a compensatory mechanism for dopaminergic neuronal loss. A new approach to the determination of dopamine turnover was developed using 4-hour-long 18F