Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jesper Torbøl, Pedersen"'
Isolation of native plasma membrane H+‐ATPase (Pma1p) in both the active and basal activation states
Publikováno v:
FEBS Open Bio, Vol 8, Iss 5, Pp 774-783 (2018)
The yeast plasma membrane H+‐ATPase Pma1p is a P‐type ATPase that energizes the yeast plasma membrane. Pma1p exists in two activation states: an autoinhibited basal state and an activated state. Here we show that functional and stable Pma1p can b
Externí odkaz:
https://doaj.org/article/505e32e1fbef40fb8a640bd8518e5dc6
Autor:
Michael G. Palmgren, Dirk Becker, Sönke Scherzer, Antonella Reyer, Khaled A. S. Al-Rascheid, Jesper Torbøl Pedersen, Georg Nagel, Melanie Häßler, Shouguang Huang, Ingo Dreyer, Rainer Hedrich, Ernst Bamberg
Publikováno v:
Proc Natl Acad Sci U S A
In plants, environmental stressors trigger plasma membrane depolarizations. Being electrically interconnected via plasmodesmata, proper functional dissection of electrical signaling by electrophysiology is basically impossible. The green alga Chlamyd
Autor:
Sara Rute Costa, Thomas Günther Pomorski, Helle Juel Martens, Daniele Silvestro, Danny Mollerup Sørensen, Henrik Waldal Holen, Jesper Torbøl Pedersen, Lyubomir Dimitrov Stanchev, Rosa L. López-Marqués, Michael G. Palmgren
Publikováno v:
Molecular Biology of the Cell
Sørensen, D M, Holen, H W, Pedersen, J T, Martens, H J, Silvestro, D, Stanchev, L D, Costa, S R, Pomorski, T G, López-Marqués, R L & Palmgren, M 2019, ' The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis ', Molecular Biology of the Cell, vol. 30, no. 9, pp. 1069-1084 . https://doi.org/10.1091/mbc.E18-06-0365
Sørensen, D M, Holen, H W, Pedersen, J T, Martens, H J, Silvestro, D, Stanchev, L D, Costa, S R, Pomorski, T G, López-Marqués, R L & Palmgren, M 2019, ' The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis ', Molecular Biology of the Cell, vol. 30, no. 9, pp. 1069-1084 . https://doi.org/10.1091/mbc.E18-06-0365
P5A ATPases are expressed in the endoplasmic reticulum (ER) of all eukaryotic cells, and their disruption results in severe ER stress. However, the function of these ubiquitous membrane proteins, which belong to the P-type ATPase superfamily, is unkn
Publikováno v:
Chemical Research in Toxicology
Inorganic arsenic is one of the most toxic and carcinogenic substances in the environment, but many organisms, including humans, methylate inorganic arsenic to mono-, di-, and trimethylated arsenic metabolites, which the organism can excrete. In huma
Autor:
Marcel Welle, Ole N. Jensen, Michael G. Palmgren, Tina Ravnsborg, Maki Hayashi, Dörte Becher, Jesper Torbøl Pedersen, Sandra Maaß, Christine Stöhr
Publikováno v:
Welle, M, Pedersen, J T, Ravnsborg, T, Hayashi, M, Maa, S, Becher, D, Jensen, O N, Stöhr, C & Palmgren, M 2021, ' A conserved, buried cysteine near the P-site is accessible to cysteine modifications and increases ROS stability in the P-Type plasma membrane H+-ATPase ', Biochemical Journal, vol. 478, no. 3, pp. 619-632 . https://doi.org/10.1042/BCJ20200559
Sulfur-containing amino acid residues function in antioxidative responses, which can be induced by the reactive oxygen species generated by excessive copper and hydrogen peroxide. In all Na+/K+, Ca2+, and H+ pumping P-type ATPases, a cysteine residue
Autor:
Pedro Lima, Custódio Oliveira Nunes, Jesper Torbøl Pedersen, Maria Teresa Portes, Michael G. Palmgren, Lene Irene Olsen, Daniel S. C. Damineli, José A. Feijó, Maki Hayashi, Claudia Guimarães Camargo Campos, Robert D. Hoffmann
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Hoffmann, R D, Portes, M T, Olsen, L I, Damineli, D S C, Hayashi, M, Nunes, C O, Pedersen, J T, Lima, P T, Campos, C, Feijó, J A & Palmgren, M 2020, ' Plasma membrane H +-ATPases sustain pollen tube growth and fertilization ', Nature Communications, vol. 11, no. 1, 2395 . https://doi.org/10.1038/s41467-020-16253-1
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Hoffmann, R D, Portes, M T, Olsen, L I, Damineli, D S C, Hayashi, M, Nunes, C O, Pedersen, J T, Lima, P T, Campos, C, Feijó, J A & Palmgren, M 2020, ' Plasma membrane H +-ATPases sustain pollen tube growth and fertilization ', Nature Communications, vol. 11, no. 1, 2395 . https://doi.org/10.1038/s41467-020-16253-1
Pollen tubes are highly polarized tip-growing cells that depend on cytosolic pH gradients for signaling and growth. Autoinhibited plasma membrane proton (H+) ATPases (AHAs) have been proposed to energize pollen tube growth and underlie cell polarity,
Autor:
Robert D. Hoffmann, Raffaele Manstretta, Jesper Torbøl Pedersen, Michael G. Palmgren, Lene Irene Olsen, Chukwuebuka Vincent Ezike, Rosa L. López-Marqués
Publikováno v:
Hoffmann, R D, Olsen, L I, Ezike, C V, Pedersen, J T, Manstretta, R, López-Marqués, R L & Palmgren, M 2019, ' Roles of plasma membrane proton ATPases AHA2 and AHA7 in normal growth of roots and root hairs in Arabidopsis thaliana ', Physiologia Plantarum, vol. 166, no. 3, pp. 848-861 . https://doi.org/10.1111/ppl.12842
Physiologia Plantarum
Physiologia Plantarum
Plasma membrane H+-ATPase pumps build up the electrochemical H+ gradients that energize most other transport processes into and out of plant cells through channel proteins and secondary active carriers. In Arabidopsis thaliana, the AUTOINHIBITED PLAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec6bb567ce0adc4545960a0de97e04a
https://curis.ku.dk/portal/da/publications/roles-of-plasma-membrane-proton-atpases-aha2-and-aha7-in-normal-growth-of-roots-and-root-hairs-in-arabidopsis-thaliana(bbe67301-1a98-4830-9ab9-64ee3db08fe8).html
https://curis.ku.dk/portal/da/publications/roles-of-plasma-membrane-proton-atpases-aha2-and-aha7-in-normal-growth-of-roots-and-root-hairs-in-arabidopsis-thaliana(bbe67301-1a98-4830-9ab9-64ee3db08fe8).html
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance People for centuries are puzzled how living creatures like plants sense their environment. Plants employ electrical signals to communicate a cue-dependent local status between plants cells and organs. As a first response to biotic and ab
Autor:
Christian B Oehlenschlæger, Anja T. Fuglsang, Astrid Kristensen, Jesper Torbøl Pedersen, Jay J. Thelen, Lotte Bettina Andersen Gersby, Nagib Ahsan, Tsvetelina V Solakova
Publikováno v:
Frontiers in Plant Science, Vol 8 (2017)
Frontiers in Plant Science
Oehlenschlæger, C B, Gersby, L B A, Ahsan, N, Pedersen, J T, Kristensen, A, Solakova, T V, Thelen, J J & Fuglsang, A T 2017, ' Activation of the LRR receptor-like kinase PSY1R requires transphosphorylation of residues in the activation loop ', Frontiers in Plant Science, vol. 8, 2005 . https://doi.org/10.3389/fpls.2017.02005
Frontiers in Plant Science
Oehlenschlæger, C B, Gersby, L B A, Ahsan, N, Pedersen, J T, Kristensen, A, Solakova, T V, Thelen, J J & Fuglsang, A T 2017, ' Activation of the LRR receptor-like kinase PSY1R requires transphosphorylation of residues in the activation loop ', Frontiers in Plant Science, vol. 8, 2005 . https://doi.org/10.3389/fpls.2017.02005
PSY1R is a leucine-rich repeat (LRR) receptor-like kinase (RLK) previously shown to act as receptor for the plant peptide hormone PSY1 (peptide containing sulfated tyrosine 1) and to regulate cell expansion. PSY1R phosphorylates and thereby regulates
Hypoxia and loss of PHD 2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis
Autor:
Emad Moeendarbary, Freja Albjerg Venning, Thomas R. Cox, Chris D. Madsen, Jesper Torbøl Pedersen, Lukram Babloo Singh, Guillaume Charras, Erik Sahai, Janine T. Erler
Publikováno v:
EMBO Reports
Cancer‐associated fibroblasts (CAFs) interact with tumour cells and promote growth and metastasis. Here, we show that CAF activation is reversible: chronic hypoxia deactivates CAFs, resulting in the loss of contractile force, reduced remodelling of