Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Jesper T, Troelsen"'
Autor:
Stine R. Wiegell, Kristoffer Hendel, Christine S.K. Fuchs, Julie Gehl, Mille Vissing, Sara W. Bro, Jesper T. Troelsen, Gregor B.E. Jemec, Merete Haedersdal
Publikováno v:
Acta Dermato-Venereologica, Vol 104 (2024)
In electrochemotherapy, permeabilization of the cell membrane by electric pulses increases the anti-tumour effect of chemotherapeutics. In calcium electroporation, chemotherapy is replaced by calcium chloride with obvious benefits. This study explore
Externí odkaz:
https://doaj.org/article/a53618ed4dac43a893a4cce587c7f25b
Autor:
Isabella W. Paulsen, Michael Bzorek, Jesper Olsen, Birgitte Grum-Schwensen, Jesper T. Troelsen, Ole B. Pedersen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Identification of target tissue microRNAs (miR) using in situ hybridization (ISH), with digoxigenin-labeled locked nucleic acid (LNA) probes, is influenced by preanalytic parameters. To determine the best retrieval method for common microRNA
Externí odkaz:
https://doaj.org/article/211e5c5c60954dffbab730b608f8181b
Autor:
Johanne Davidsen, Stine Bull Jessen, Sara Kehlet Watt, Sylvester Larsen, Katja Dahlgaard, Tove Kirkegaard, Ismail Gögenur, Jesper T. Troelsen
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Colon cancer is one of the most commonly diagnosed types of cancer with surgical resection of the tumor being the primary choice of treatment. However, the surgical stress response induced during treatment may be related to a high
Externí odkaz:
https://doaj.org/article/eba229a27dc84e4fbfbc33651debd881
Colorectal cancer-associated SNP rs17042479 is involved in the regulation of NAF1 promoter activity.
Autor:
Josephine B Olsson, Marietta B Gugerel, Stine B Jessen, Jannie Jørgensen, Ismail Gögenur, Camilla Hansen, Lene T Kirkeby, Jørgen Olsen, Ole B V Pedersen, Peter M Vestlev, Katja Dahlgaard, Jesper T Troelsen
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274033 (2022)
A novel risk locus at 4q32.2, located between the Nuclear Assembly Factor 1 (NAF1) and Follistatin Like 5 (FSTL5) genes, was associated with increased risk of developing colorectal cancer (CRC), with SNP rs17042479 being the most associated. However,
Externí odkaz:
https://doaj.org/article/cbbae98fee5b4b73878dbb965057c357
Autor:
Stefan Bengtson, Kristina B Knudsen, Zdenka O Kyjovska, Trine Berthing, Vidar Skaug, Marcus Levin, Ismo K Koponen, Abhay Shivayogimath, Timothy J Booth, Beatriz Alonso, Amaia Pesquera, Amaia Zurutuza, Birthe L Thomsen, Jesper T Troelsen, Nicklas R Jacobsen, Ulla Vogel
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178355 (2017)
We investigated toxicity of 2-3 layered >1 μm sized graphene oxide (GO) and reduced graphene oxide (rGO) in mice following single intratracheal exposure with respect to pulmonary inflammation, acute phase response (biomarker for risk of cardiovascul
Externí odkaz:
https://doaj.org/article/abd8bc892bfb4c1193d79e55bec78894
Autor:
Claus Henrik Nielsen, Jakob Benedict Seidelin, Mehmet Coşkun, Sylvester Larsen, Ole Birger Pedersen, Eric P. Bennett, Jesper T. Troelsen, Johanne Davidsen, Katja Dahlgaard
Publikováno v:
FEBS Open Bio, Vol 11, Iss 6, Pp 1638-1644 (2021)
FEBS Open Bio
Larsen, S, Seidelin, J B, Davidsen, J, Dahlgaard, K, Nielsen, C H, Bennett, E P, Pedersen, O B, Coskun, M & Troelsen, J T 2021, ' CDX2 regulates interleukin-33 gene expression in intestinal epithelial cells (LS174T) ', FEBS Open Bio, vol. 11, no. 6, pp. 1638-1644 . https://doi.org/10.1002/2211-5463.13161
FEBS Open Bio
Larsen, S, Seidelin, J B, Davidsen, J, Dahlgaard, K, Nielsen, C H, Bennett, E P, Pedersen, O B, Coskun, M & Troelsen, J T 2021, ' CDX2 regulates interleukin-33 gene expression in intestinal epithelial cells (LS174T) ', FEBS Open Bio, vol. 11, no. 6, pp. 1638-1644 . https://doi.org/10.1002/2211-5463.13161
Dysregulation of interleukin‐33 (IL‐33) has been implicated in the pathogenesis of several autoimmune and inflammatory diseases, but few studies have examined transcriptional regulation of the IL33 gene. In the intestines, gene regulation is cont
Autor:
Steffen Jørgensen, Mehmet Coskun, Keld Mikkelsen Homburg, Ole B V Pedersen, Jesper T Troelsen
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164555 (2016)
The mammalian Caudal-related homeobox transcription factor 2 (CDX2) plays a key role in the homeobox regulatory network and is essential in regulating the expression of several homeobox (HOX) genes during embryonic development, particularly in the gu
Externí odkaz:
https://doaj.org/article/c35f1cd373f647ab907bac68dc3b5d10
Publikováno v:
Jessen, S B, Özkul, D C, Özen, Y, Gögenur, I & Troelsen, J T 2022, ' Establishment of a luciferase-based method for measuring cancer cell adhesion and proliferation ', Analytical Biochemistry, vol. 650, 114723 . https://doi.org/10.1016/j.ab.2022.114723
Background: Methods measuring cell proliferation and adhesion are widely used but each hold limitations. We, therefore, introduce novel methods for measuring cell proliferation and adhesion based on CRISPR-modified cancer cell lines secreting lucifer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a9f585b108b744c878662c9d73a781
https://curis.ku.dk/portal/da/publications/establishment-of-a-luciferasebased-method-for-measuring-cancer-cell-adhesion-and-proliferation(5a54b254-c30b-4da1-9ff6-989b52a7d088).html
https://curis.ku.dk/portal/da/publications/establishment-of-a-luciferasebased-method-for-measuring-cancer-cell-adhesion-and-proliferation(5a54b254-c30b-4da1-9ff6-989b52a7d088).html
Autor:
E Thomas Danielsen, Morten E Moeller, Elad Dorry, Tatsuya Komura-Kawa, Yoshinori Fujimoto, Jesper T Troelsen, Rachel Herder, Michael B O'Connor, Ryusuke Niwa, Kim F Rewitz
Publikováno v:
PLoS Genetics, Vol 10, Iss 6, p e1004343 (2014)
Specialized endocrine cells produce and release steroid hormones that govern development, metabolism and reproduction. In order to synthesize steroids, all the genes in the biosynthetic pathway must be coordinately turned on in steroidogenic cells. I
Externí odkaz:
https://doaj.org/article/3490f207b31f428ca388c1af1cc6a9c2
Autor:
Malene Broholm, Ismail Gögenur, Anne-Marie Kanstrup Fiehn, Jens Eriksen, Thomas Litman, Jesper T. Troelsen, Sara Furbo, Lise Mette Rahbek Gjerdrum, Thea Helene Degett, Mustafa Bulut
Publikováno v:
Annals of surgical oncology. 28(13)
Background Colonic stent is recommended as a bridge to elective surgery for malignant obstruction to improve short-term clinical outcomes for patients with colorectal cancer. However, since the oncological outcomes remain controversial, this study ai