Výsledky vyhledávání - "Jesper Søborg Bahnsen"

Selenium as an alternative peptide label – comparison to fluorophore-labelled penetratin

Autor: Hanne Mørck Nielsen, Jesper Østergaard, Bente Gammelgaard, Laura Hyrup Møller, Stefan Stürup, Jesper Søborg Bahnsen

Publikováno v: European Journal of Pharmaceutical Sciences. 67:76-84

In the present study, the impact on peptide properties of labelling peptides with the fluorophore TAMRA or the selenium (Se) containing amino acid SeMet was evaluated. Three differently labelled variants of the cell-penetrating peptide (CPP) penetrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf6dadaa969d7b27486f58841c1b022
https://doi.org/10.1016/j.ejps.2014.11.001

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Antimicrobial and cell-penetrating properties of penetratin analogs: Effect of sequence and secondary structure

Autor: Anne Sandberg-Schaal, Henrik Franzyk, Jesper Søborg Bahnsen, Hanne Mørck Nielsen

Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828:223-232

Cell-penetrating peptides (CPPs) and antimicrobial peptides (AMPs) show great potential as drug delivery vectors and new antibiotic drug entities, respectively. The current study deals with the properties of a variety of peptide analogs derived from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbfa244d7173246eaa26d28a0d91f47
https://doi.org/10.1016/j.bbamem.2012.10.010

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Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections

Autor: Jesper Søborg Bahnsen, Hanne Mørck Nielsen, Arwyn Tomos Jones, Henrik Franzyk, Edward J. Sayers

Purpose. To investigate the suitability of three antimicrobial peptides (AMPs) as cellpenetrating\ud antimicrobial peptides.\ud Methods. Cellular uptake of three AMPs (PK-12-KKP, SA-3 and TPk) and a cellpenetrating\ud peptide (penetratin), all 5(6)-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29efbc40472cc5d8de61d1cbeb3197a2
https://orca.cardiff.ac.uk/id/eprint/67643/7/PHAM-S-14-00601_submitted.pdf

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Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation

Autor: Rikke Bjerring Skyggebjerg, Hanne Mørck Nielsen, Mie Kristensen, Jesper Søborg Bahnsen, Mia Thorne Klausen, Vito Foderà, Henrik Franzyk, Anne Iversen

Publikováno v: The AAPS journal. 17(5)

Penetratin is a widely used carrier peptide showing promising potential for mucosal delivery of therapeutic proteins. In the present study, the importance of specific penetratin residues and pH was investigated with respect to complexation with insul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b6c0a2ae23783976e074faebae6b3d
https://pubmed.ncbi.nlm.nih.gov/25990963

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Quantification of pharmaceutical peptides using selenium as an elemental detection label

Autor: Henrik Franzyk, Bente Gammelgaard, Charlotte Gabel-Jensen, Stefan Stürup, Jesper Søborg Bahnsen, Laura Hyrup Møller

Publikováno v: Møller, L H, Gabel-Jensen, C, Franzyk, H, Bahnsen, J S, Stürup, S & Gammelgaard, B 2014, ' Quantification of pharmaceutical peptides using selenium as an elemental detection label ', Metallomics : integrated biometal science, vol. 6, pp. 1639-1647 . https://doi.org/10.1039/c4mt00085d

The aim of the present work was to demonstrate how selenium labelling of a synthetic cell-penetrating peptide may be employed in evaluation of stability and quantitative estimation of cellular uptake by inductively coupled plasma mass spectrometry (I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b9c1bdcda99f0de6a5ab44b2b5e53c
https://curis.ku.dk/portal/da/publications/quantification-of-pharmaceutical-peptides-using-selenium-as-an-elemental-detection-label(de96c161-851e-46ac-b57c-91bbac9cbb3d).html

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