Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jesper R. Nilsson"'
Autor:
Jesper R. Nilsson, Tom Baladi, Audrey Gallud, Dženita Baždarević, Malin Lemurell, Elin K. Esbjörner, L. Marcus Wilhelmsson, Anders Dahlén
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract To expand the antisense oligonucleotide (ASO) fluorescence labeling toolbox beyond covalent conjugation of external dyes (e.g. ATTO-, Alexa Fluor-, or cyanine dyes), we herein explore fluorescent base analogues (FBAs) as a novel approach to
Externí odkaz:
https://doaj.org/article/8abf403a3bcb4d9fa1479c960effbb9d
Autor:
Mattias Bood, Anna Wypijewska del Nogal, Jesper R. Nilsson, Fredrik Edfeldt, Anders Dahlén, Malin Lemurell, L. Marcus Wilhelmsson, Morten Grøtli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The aberrant expression of microRNAs (miRs) has been linked to several human diseases. A promising approach for targeting these anomalies is the use of small-molecule inhibitors of miR biogenesis. These inhibitors have the potential to (i) d
Externí odkaz:
https://doaj.org/article/cda9c7e7160e4417b694ff5cf0c29da7
Autor:
Pauline Pfeiffer, Tom Brown, Jesper R. Nilsson, Anders Dahlén, Mattias Bood, Anders Foller Füchtbauer, Marcus Wilhelmsson, Afaf H. El-Sagheer, Anna Wiktoria Wypijewska Del Nogal, Vinoth Sundar Rajan, Sangamesh Sarangamath, Morten Grøtli, Moa Sandberg Wranne
Publikováno v:
Nucleic Acids Research
With the central role of nucleic acids there is a need for development of fluorophores that facilitate the visualization of processes involving nucleic acids without perturbing their natural properties and behaviour. Here, we incorporate a new analog
Autor:
Mariell Pettersson, David Bliman, Jimmy Jacobsson, Jesper R Nilsson, Jaeki Min, Luigi Iconaru, R Kiplin Guy, Richard W Kriwacki, Joakim Andréasson, Morten Grøtli
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124423 (2015)
Small molecule nonpeptidic mimics of α-helices are widely recognised as protein-protein interaction (PPIs) inhibitors. Protein-protein interactions mediate virtually all important regulatory pathways in a cell, and the ability to control and modulat
Externí odkaz:
https://doaj.org/article/6029b62f2cd9436aa042c3db3168a3cb
Autor:
Erik Weis, Anders Foller Füchtbauer, Pauline Pfeiffer, Mattias Bood, Jesper R. Nilsson, Anders Dahlén, Marcus Wilhelmsson, Moa Sandberg Wranne, Morten Grøtli
Publikováno v:
Nucleic Acids Research
Published by Oxford University Press on behalf of Nucleic Acids Research. Interbase FRET can reveal highly detailed information about distance, orientation and dynamics in nucleic acids, complementing the existing structure and dynamics techniques. W
Autor:
Marcus Wilhelmsson, Jesper R. Nilsson, Malin Lemurell, Fredrik Edfeldt, Mattias Bood, Morten Grøtli, Anders Dahlén, Anna Wiktoria Wypijewska Del Nogal
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
The aberrant expression of microRNAs (miRs) has been linked to several human diseases. A promising approach for targeting these anomalies is the use of small-molecule inhibitors of miR biogenesis. These inhibitors have the potential to (i) dissect mi
Autor:
Tom Baladi, Audrey Gallud, Malin Lemurell, L. Marcus Wilhelmsson, Elin K. Esbjörner, Dženita Baždarević, Anders Dahlén, Jesper R. Nilsson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
To expand the antisense oligonucleotide (ASO) fluorescence labeling toolbox beyond covalent conjugation of external dyes (e.g. ATTO-, Alexa Fluor-, or cyanine dyes), we herein explore fluorescent base analogues (FBAs) as a novel approach to endow flu
Autor:
Elin K. Esbjörner, Jesper R. Nilsson, Audrey Gallud, Marcel Hollenstein, Cécile Gasse, Emanuele Celauro, Anders Dahlén, Fabienne Levi-Acobas, Tom Baladi, Ivo Sarac, L. Marcus Wilhelmsson
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 2021, 143 (14), pp.5413-5424. ⟨10.1021/jacs.1c00014⟩
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (14), pp.5413-5424. ⟨10.1021/jacs.1c00014⟩
Journal of the American Chemical Society, 2021, 143 (14), pp.5413-5424. ⟨10.1021/jacs.1c00014⟩
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (14), pp.5413-5424. ⟨10.1021/jacs.1c00014⟩
International audience; Methods for tracking RNA molecules inside living cells without perturbing their natural interactions and functions are critical within biology and, in particular, to facilitate studies of therapeutic RNA delivery. We present a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7d2187355619e1957adc2defc6f7db
https://doi.org/10.1101/2020.07.01.172767
https://doi.org/10.1101/2020.07.01.172767
Autor:
Ville Saarnio, Jesper R. Nilsson, Visa Ruokolainen, L. Marcus Wilhelmsson, Kirsi Salorinne, Tiia-Riikka Tero, Varpu Marjomäki, Sami Oikarinen, Tanja Lahtinen
Publikováno v:
Dyes and Pigments. 177:108282
Fluorescent probes for sensing nucleic acids have found widespread use in the field of cell and molecular biology. However, probes combined with potential for post-synthetic conjugation, e.g. for intra-endosomal measurements of RNA, are unavailable.
Publikováno v:
Chemistry-A European Journal (0947-6539) vol.20(2014)
Two amidine-substituted spiropyran derivatives have been characterized with respect to the DNA-binding properties over a broad pH interval. The two derivatives differ in the number of positive charges. By varying the pH, the protonation state of the