Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Jesper Nylandsted"'
Autor:
Volker Gerke, Felicity N. E. Gavins, Michael Geisow, Thomas Grewal, Jyoti K. Jaiswal, Jesper Nylandsted, Ursula Rescher
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Annexins are cytosolic proteins with conserved three-dimensional structures that bind acidic phospholipids in cellular membranes at elevated Ca2+ levels. Through this they act as Ca2+-regulated membrane binding modules that organize membrane
Externí odkaz:
https://doaj.org/article/0372b0d39f0048d4a7ebd22615898ab9
Autor:
Malene Laage Ebstrup, Stine Lauritzen Sønder, Ditte Louise Fogde, Anne Sofie Busk Heitmann, Tiina Naumanen Dietrich, Catarina Dias, Marja Jäättelä, Kenji Maeda, Jesper Nylandsted
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Lysosomes are crucial organelles essential for various cellular processes, and any damage to them can severely compromise cell viability. This study uncovers a previously unrecognized function of the calcium- and phospholipid-binding protein Annexin
Externí odkaz:
https://doaj.org/article/bd1103947a9b433d9ba7b5a9098218ad
Autor:
Catarina Dias, Jesper Nylandsted
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 7, Pp 1399-1400 (2024)
Externí odkaz:
https://doaj.org/article/153cf12765534ee2af4aebfd2fa055c3
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The limitations of current cancer therapies, including the increasing prevalence of multidrug resistance, underscore the urgency for more effective treatments. One promising avenue lies in the repurposing of existing drugs. This review explores the i
Externí odkaz:
https://doaj.org/article/d55abb40bd9f4067b351fd9c449635aa
Autor:
Anna Mularski, Stine Lauritzen Sønder, Anne Sofie Busk Heitmann, Mayank Prakash Pandey, Himanshu Khandelia, Jesper Nylandsted, Adam Cohen Simonsen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Efficient plasma membrane repair (PMR) is required to repair damage sustained in the cellular life cycle. The annexin family of proteins, involved in PMR, are activated by Ca2+ influx from extracellular media at the site of injury. Mechanist
Externí odkaz:
https://doaj.org/article/fc244366550b4d8d8d1720e03effac7a
Autor:
Natascha Leijnse, Younes Farhangi Barooji, Mohammad Reza Arastoo, Stine Lauritzen Sønder, Bram Verhagen, Lena Wullkopf, Janine Terra Erler, Szabolcs Semsey, Jesper Nylandsted, Lene Broeng Oddershede, Amin Doostmohammadi, Poul Martin Bendix
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The authors show how tubular surface structures in all cell types, have the ability to twist and perform rotary sweeping motion to explore the extracellular environment. This has implications for migration, sensing and cell communication.
Externí odkaz:
https://doaj.org/article/3b19980656f94b5e89838b8bd1184075
Autor:
Swantje Christin Häger, Catarina Dias, Stine Lauritzen Sønder, André Vidas Olsen, Isabelle da Piedade, Anne Sofie Busk Heitmann, Elena Papaleo, Jesper Nylandsted
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Plasma membrane repair mechanisms are activated within seconds post-injury to promote rapid membrane resealing in eukaryotic cells and prevent cell death. However, less is known about the regeneration phase that follows and how cells respond
Externí odkaz:
https://doaj.org/article/99adb3dc3d88401b94736e0dc7c6ae80
Publikováno v:
Bio-Protocol, Vol 12, Iss 11 (2022)
Damage to the plasma membrane and loss of membrane integrity are detrimental to eukaryotic cells. It is, therefore, essential that cells possess an efficient membrane repair system to survive. However, the different cellular and molecular mechanisms
Externí odkaz:
https://doaj.org/article/bf6969f7c5af40c8b5821993a5b5a6f4
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Plasma membrane repair is essential for eukaryotic cell life and is triggered by the influx of calcium through membrane wounds. Repair consists of sequential steps, with closure of the membrane hole being the key event that allows the cell t
Externí odkaz:
https://doaj.org/article/cb50f1d96543458da9d5ea6e6d198add
Autor:
Catarina Dias, Jesper Nylandsted
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-18 (2021)
Abstract Maintenance of plasma membrane integrity is essential for normal cell viability and function. Thus, robust membrane repair mechanisms have evolved to counteract the eminent threat of a torn plasma membrane. Different repair mechanisms and th
Externí odkaz:
https://doaj.org/article/b59302177b4f43fe9eb81320e57f69ab