Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Jesper Hagemeier"'
Autor:
Dejan Jakimovski, Jens Kuhle, Murali Ramanathan, Christian Barro, Davorka Tomic, Jesper Hagemeier, Harald Kropshofer, Niels Bergsland, David Leppert, Michael G. Dwyer, Zuzanna Michalak, Ralph H. B. Benedict, Bianca Weinstock‐Guttman, Robert Zivadinov
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 9, Pp 1757-1770 (2019)
Abstract Background Gray matter (GM) pathology is closely associated with physical and cognitive impairment in persons with multiple sclerosis (PwMS). Similarly, serum neurofilament light chain (sNfL) levels are related to MS disease activity and pro
Externí odkaz:
https://doaj.org/article/fa2395b281e14fb8bdb3a64daa5654e4
Autor:
Kelly Fellows Maxwell, Sonia Bhattacharya, Mary Lou Bodziak, Dejan Jakimovski, Jesper Hagemeier, Richard W. Browne, Bianca Weinstock-Guttman, Robert Zivadinov, Murali Ramanathan
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1190-1198 (2019)
The purpose of this work was to investigate whether changes in oxysterol and apolipoprotein levels over 5 years are associated with disease course and disability progression in multiple sclerosis (MS). This study included 139 subjects [39 healthy con
Externí odkaz:
https://doaj.org/article/4a9fcc510e5c4ce78fefa22e73336c36
Autor:
Sirin Gandhi, Karen Marr, Marcello Mancini, Maria Grazia Caprio, Dejan Jakimovski, Avinash Chandra, Jesper Hagemeier, David Hojnacki, Channa Kolb, Bianca Weinstock-Guttman, Robert Zivadinov
Publikováno v:
BMC Neurology, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background No longitudinal, long-term, follow-up studies have explored the association between presence and severity of variations in extracranial venous anatomy, and clinical outcomes in patients with multiple sclerosis (MS). Objective This
Externí odkaz:
https://doaj.org/article/7a253cb3fa7842fda1d4de46bd669328
Autor:
Dejan Jakimovski, Robert Zivadinov, Niels Bergsland, Deepa P. Ramasamy, Jesper Hagemeier, Antonia Valentina Genovese, David Hojnacki, Bianca Weinstock-Guttman, Michael G. Dwyer
Publikováno v:
NeuroImage: Clinical, Vol 29, Iss , Pp 102554- (2021)
Background: Greater brain atrophy is associated with disability progression (DP) in patients with multiple sclerosis (PwMS). However, methodological challenges limit its routine clinical use. Objective: To determine the feasibility of atrophy measure
Externí odkaz:
https://doaj.org/article/786cac2179b04be585eb7e9addb96d02
Autor:
Dejan Jakimovski, Niels Bergsland, Michael G. Dwyer, John Traversone, Jesper Hagemeier, Tom A. Fuchs, Deepa P. Ramasamy, Bianca Weinstock-Guttman, Ralph H. B. Benedict, Robert Zivadinov
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Reports suggest presence of cerebral hypoperfusion in multiple sclerosis (MS). Currently there are no studies that examine if the cerebral MS perfusion is affected by presence of cardiovascular comorbidities.Objective: To investigate asso
Externí odkaz:
https://doaj.org/article/83b6f80a2d0c4f2db56b9509e7f5e4c0
Autor:
Jesper Hagemeier, Robert Zivadinov, Michael G. Dwyer, Paul Polak, Niels Bergsland, Bianca Weinstock-Guttman, Joshua Zalis, Andreas Deistung, Jürgen R. Reichenbach, Ferdinand Schweser
Publikováno v:
NeuroImage: Clinical, Vol 18, Iss , Pp 1007-1016 (2018)
In multiple sclerosis, pathological changes of both tissue iron and myelin occur, yet these factors have not been characterized in a longitudinal fashion using the novel iron- and myelin-sensitive quantitative susceptibility mapping (QSM) MRI techniq
Externí odkaz:
https://doaj.org/article/178e8d910e2943f5864fef0163bffdaa
Autor:
Jesper Hagemeier, Murali Ramanathan, Ferdinand Schweser, Michael G. Dwyer, Fuchun Lin, Niels Bergsland, Bianca Weinstock-Guttman, Robert Zivadinov
Publikováno v:
NeuroImage: Clinical, Vol 17, Iss , Pp 530-540 (2018)
Brain iron homeostasis is known to be disturbed in multiple sclerosis (MS), yet little is known about the association of common gene variants linked to iron regulation and pathological tissue changes in the brain. In this study, we investigated the a
Externí odkaz:
https://doaj.org/article/d24d8251e8e84d728e0da655839a0955
Autor:
Michael G. Dwyer, Jesper Hagemeier, Niels Bergsland, Dana Horakova, Jonathan R. Korn, Nasreen Khan, Tomas Uher, Jennie Medin, Diego Silva, Manuela Vaneckova, Eva Kubala Havrdova, Robert Zivadinov
Publikováno v:
NeuroImage: Clinical, Vol 18, Iss , Pp 494-501 (2018)
Background: A percent brain volume change (PBVC) cut-off of −0.4% per year has been proposed to distinguish between pathological and physiological changes in multiple sclerosis (MS). Unfortunately, standardized PBVC measurement is not always feasib
Externí odkaz:
https://doaj.org/article/043a9280fcbf40a292d1e4263123cb93
Autor:
Karthikeyan Subramanian, David Utriainen, Deepa P. Ramasamy, Sean K. Sethi, Ferdinand Schweser, John Beaver, Jesper Hagemeier, Bianca Weinstock-Guttman, Rajasimhan Rajagovindan, Robert Zivadinov, Ewart Mark Haacke
Publikováno v:
Diagnostics, Vol 10, Iss 11, p 942 (2020)
We hypothesized that cerebral microbleeds (CMBs) in multiple sclerosis (MS) patients will be detected with higher prevalence compared to healthy controls (HC) and that quantitative susceptibility mapping (QSM) will help remove false positives seen in
Externí odkaz:
https://doaj.org/article/9a861f730cfd401da7dbb942d2f9b009
Autor:
Elliot Graziano, Jesper Hagemeier, Bianca Weinstock-Guttman, Deepa P. Ramasamy, Robert Zivadinov
Publikováno v:
NeuroImage: Clinical, Vol 9, Iss C, Pp 110-116 (2015)
Background and objectives: While the literature supports the idea that multiple sclerosis (MS) and migraine are related, the exact mechanism(s) of this association is not well understood. Observations of increased contrast enhancing (CE) lesion activ
Externí odkaz:
https://doaj.org/article/d591eb8ee7a64479b5cea3f081153799