Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jesper Falkesgaard, Højen"'
Autor:
Liqiong Jiang, Lars P. Lunding, William S. Webber, Karsten Beckmann, Tania Azam, Jesper Falkesgaard Højen, Jesus Amo-Aparicio, Alberto Dinarello, Tom T. Nguyen, Ulrich Pessara, Daniel Parera, David J. Orlicky, Stephan Fischer, Michael Wegmann, Charles A. Dinarello, Suzhao Li
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionInterleukin-18 (IL-18), a pro-inflammatory cytokine belonging to the IL-1 Family, is a key mediator ofautoinflammatory diseases associated with the development of macrophage activation syndrome (MAS).High levels of IL-18 correlate with MA
Externí odkaz:
https://doaj.org/article/043b9fc676264481860d024fe524374a
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background Parkinson’s disease (PD) is characterized by a progressive degeneration of dopaminergic neurons, which leads to irreversible loss of peripheral motor functions. Death of dopaminergic neurons induces an inflammatory response in m
Externí odkaz:
https://doaj.org/article/9e771736560b44e886618201a2fdbb1f
Autor:
Janne Tegder Martinsen, Jesper Damsgaard Gunst, Jesper Falkesgaard Højen, Martin Tolstrup, Ole Schmeltz Søgaard
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Toll-like receptors (TLRs) are a family of pattern recognition receptors and part of the first line of defense against invading microbes. In humans, we know of 10 different TLRs, which are expressed to varying degrees in immune cell subsets. Engaging
Externí odkaz:
https://doaj.org/article/2d2ae08d083e469fb439c0dbbedddd49
Autor:
Xianglei Yan, Sebastian Ols, Rodrigo Arcoverde Cerveira, Klara Lenart, Fredrika Hellgren, Kewei Ye, Alberto Cagigi, Marcus Buggert, Falk Nimmerjahn, Jesper Falkesgaard Højen, Daniel Parera, Ulrich Pessara, Stephan Fischer, Karin Loré
Targeting CD40 by agonistic antibodies used as vaccine adjuvants or for cancer immunotherapy is a strategy to stimulate immune responses. The majority of studied agonistic anti-human CD40 antibodies require crosslinking of their Fc region to inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b921dd999272eb6a39b16fa62a7a0b2
https://doi.org/10.1101/2023.03.22.533762
https://doi.org/10.1101/2023.03.22.533762
Autor:
Christel Rothe Brinkmann, Jesper Falkesgaard Højen, Thomas Aagaard Rasmussen, Anne Sofie Kjær, Rikke Olesen, Paul W. Denton, Lars Østergaard, Zhengyu Ouyang, Mathias Lichterfeld, Xu Yu, Ole Schmeltz Søgaard, Charles Dinarello, Martin Tolstrup
Publikováno v:
mSphere, Vol 3, Iss 1 (2018)
ABSTRACT Histone deacetylase inhibitors (HDACi) modulate the transcriptional activity of all cells, including innate and adaptive immune cells. Therefore, we aimed to evaluate immunological effects of treatment with the HDACi panobinostat in HIV-infe
Externí odkaz:
https://doaj.org/article/42a41f93e9564a62ab717ed0df2a75eb
Autor:
Christel Rothe, Brinkmann, Jesper Falkesgaard, Højen, Thomas Aagaard, Rasmussen, Anne Sofie, Kjær, Rikke, Olesen, Paul W, Denton, Lars, Østergaard, Zhengyu, Ouyang, Mathias, Lichterfeld, Xu, Yu, Ole Schmeltz, Søgaard, Charles, Dinarello, Martin, Tolstrup
Publikováno v:
mSphere
The effect of treatment with histone deacetylase inhibitors on the immune system in HIV-infected individuals is not clear. Analysis of results from a clinical trial in which 15 HIV-infected individuals received 12 doses of panobinostat identified a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09e95ccfacf73e16544d540d735c53dc
https://pubmed.ncbi.nlm.nih.gov/29468194
https://pubmed.ncbi.nlm.nih.gov/29468194