Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jesper Brohede"'
Autor:
Helena Karlström, Lena Lilius, Louise Hedskog, Birgitta Wiehager, Catarina Moreira Pinho, Elzbieta Glaser, Caroline Graff, Maria Ankarcrona, Jesper Brohede, Priya Revathikumar
Publikováno v:
Journal of Alzheimer's Disease. 31:527-536
The apolipoprotein E (APOE) gene remains the most strongly established risk factor for late onset Alzheimer's disease (LOAD). Recently the gene, TOMM40, which is in linkage disequilibrium with APOE, was identified to be associated with LOAD in genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e53434138fd898538e09bcfe5035381
https://doi.org/10.3233/jad-2012-120580
https://doi.org/10.3233/jad-2012-120580
Autor:
Huei-Hsin Chiang, Tiina Robins, Inger Nennesmo, Behnosh F. Björk, Lina Rosvall, Karin Axelman, Caroline Graff, Jesper Brohede
Publikováno v:
Alzheimer's & Dementia. 4:414-420
Background Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by cognitive impairment, language dysfunction, and/or changes in personality. Recently it has been shown that progranulin ( GRN ) mutations can cause FTD as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85c87856a71ada29120211b84bc41bd
https://doi.org/10.1016/j.jalz.2008.09.001
https://doi.org/10.1016/j.jalz.2008.09.001
Autor:
David A. Mackey, Liesel M. FitzGerald, Joanne L. Dickinson, Stephen Quinn, Andrea M. Polanowski, Jim Stankovich, Russell Thomson, Simon J. Foote, Timothy A. Thornton, Jesper Brohede, Briony Patterson, Garry N. Hannan, Terence Dwyer, David Challis, James McKay
Publikováno v:
European Journal of Human Genetics. 17:368-377
Genetic heterogeneity is a difficulty frequently encountered in the search for genes conferring susceptibility to prostate cancer. To circumvent this issue, we selected a large prostate cancer pedigree for genome-wide linkage analysis from a populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ef95bd0e4f1df54259943ddbdc137f
https://doi.org/10.1038/ejhg.2008.171
https://doi.org/10.1038/ejhg.2008.171
Publikováno v:
Prenatal Diagnosis. 27:1197-1204
Objective To evaluate the ability of a DNA single nucleotide polymorphism (SNP) microarray to detect chromosome mosaicism for trisomy in prenatal samples in order to compare this with conventional cytogenetics. Method We created a dilution series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7371473bc30a2bfa090a1502c8f82a1c
https://doi.org/10.1002/pd.1884
https://doi.org/10.1002/pd.1884
Publikováno v:
Behavioral Ecology. 14(5):707-712
We tested the novel hypothesis that arrival date in migratory birds represents a reliable indicator of male quality that can be used by females as a cue in extrapair mating decisions. Secondary sexual characters are often condition-dependent, and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9416093267a30c098cc47b7f3516a4
http://hdl.handle.net/10.1093/beheco/arg051
http://hdl.handle.net/10.1093/beheco/arg051
Autor:
Glenn S. Brown, Garry N. Hannan, Finlay A. Macrae, Gabriel Capellá, Ignacio Blanco, Ian W Saunders, Peter L. Molloy, Victor Moreno, Trevor Lockett, Graeme P. Young, Diana Brookes, Jesper Brohede, Jason P. Ross
Publikováno v:
European journal of human genetics : EJHG. 20(1)
Up to 25% of colorectal cancer (CRC) may be caused by inherited genetic variants that have yet to be identified. Previous genome-wide linkage studies (GWLSs) have identified a new loci postulated to contain novel CRC risk genes amongst affected famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4c673ac1aef4e9a2262695351a0e42
https://pubmed.ncbi.nlm.nih.gov/21829229
https://pubmed.ncbi.nlm.nih.gov/21829229
Autor:
Anna Sillén, Lena Lilius, Toru Kimura, Jorge Andrade, Bengt Winblad, Charlotte Forsell, Jacob Odeberg, Caroline Graff, Jesper Brohede
Publikováno v:
Dementia and geriatric cognitive disorders. 31(2)
Background/Aims: We have previously reported the results of an extended genome-wide scan of Swedish Alzheimer disease (AD)-affected families; in this paper, we analyzed a subset of these families with autopsy-confirmed AD. Methods: We report the fine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82356a532b4ed51acb1f4b596f320173
https://pubmed.ncbi.nlm.nih.gov/21273770
https://pubmed.ncbi.nlm.nih.gov/21273770
Publikováno v:
Journal of neurogenetics. 24(4)
Presence of extracellular amyloid plaques is a neuropathological hallmark of Alzheimer disease. Here the authors have compared the methylation status of a CpG-island in the amyloid precursor protein gene (APP) in DNA extracted from the more plaque-vu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8658e9b69a12e4b43d2e5625480d36
https://pubmed.ncbi.nlm.nih.gov/20919856
https://pubmed.ncbi.nlm.nih.gov/20919856
Autor:
Jorge Andrade, Jesper Brohede, Lena Lilius, Jacob Odeberg, Bengt Winblad, Charlotte Forsell, Hayao Ebise, Caroline Graff, Anna Sillén
Publikováno v:
Journal of human genetics. 55(10)
This study aimed at identifying novel susceptibility genes for a mixed phenotype of Alzheimer's disease and vascular dementia. Results from a genome scan showed strongest linkage to 20p13 in 18 families, and subsequent fine mapping was performed with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f49ac8a03e070350d4c5fcabbe141f0
https://pubmed.ncbi.nlm.nih.gov/20596041
https://pubmed.ncbi.nlm.nih.gov/20596041
Autor:
Charlotte Forsell, Bengt Winblad, Jorge Andrade, Toru Kimura, Caroline Graff, Anna Sillén, Jacob Odeberg, Lena Lilius, Jesper Brohede
Publikováno v:
Alzheimer's & Dementia. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53dbdb45296a617300cb7d4f0502e3d4
https://doi.org/10.1016/j.jalz.2010.05.611
https://doi.org/10.1016/j.jalz.2010.05.611