Differences in Elastin and Elastolytic Enzymes between Men and Women with Abdominal Aortic Aneurysm

Autor: Rebecka Hultgren, Per Eriksson, Christina Villard, Jesper Swedenborg

Publikováno v: AORTA. 2:179-185

Background: Abdominal aortic aneurysms (AAAs) in women differ in some important aspects from those in men. The lower prevalence rate, higher rupture rate and potentially increased growth rate in women with AAA suggest gender to be of importance for a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e902843391a3bb6ba946384a28c9267c
https://doi.org/10.12945/j.aorta.2014.14-017

Serine protease inhibitor A3 in atherosclerosis and aneurysm disease

Autor: Anton Razuvaev, Vincent Fontaine, Charlotta Hjerpe, Xinghua Zhou, Johannes Wilbertz, Dick Wågsäter, Per Eriksson, Jesper Swedenborg, Alexandra Bäcklund, Emina Vorkapic, Anders Hamsten, Kenneth Caidahl, Mikko I. Mäyränpää, Anders Franco-Cereceda, Daniel X. Johansson

Publikováno v: International Journal of Molecular Medicine; Vol

Remodeling of extracellular matrix (ECM) plays an important role in both atherosclerosis and aneurysm disease. Serine protease inhibitor A3 (serpinA3) is an inhibitor of several proteases such as elastase, cathepsin G and chymase derived from mast ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638ddcfe541cdaeb21d342d96cc12fba
https://doi.org/10.3892/ijmm.2012.994

Mast Cells

Autor: Jesper Swedenborg, Mikko I. Mäyränpää, Petri T. Kovanen

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 31:734-740

Mast cells (MCs) regulate inflammation and immunity. Their granular content includes heparin, histamine, and several enzymes (tryptase, chymase, carboxypeptidase, and cathepsin G). In addition, activated MCs synthesize and release eicosanoids and a l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63b76fc8f5c50976de86349887a44e3
https://doi.org/10.1161/atvbaha.110.213157

High Frequency of Thoracic Aneurysms in Patients with Abdominal Aortic Aneurysms

Autor: Jesper Swedenborg, Lia Vishnevskaya, Emma Larsson, Rebecka Hultgren, Bo Kalin, Fredrik Granath

Publikováno v: Annals of Surgery. 253:180-184

To investigate the prevalence of thoracic aortic aneurysms (TAA) in patients with abdominal aortic aneurysms (AAA).Different disease profiles between men and women treated for AAA have been reported. Reports regarding causes of death for treated AAA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f4e361cf2cc3dc599c78cc766548dc
https://doi.org/10.1097/sla.0b013e3181d96498

Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans

Autor: Gillian Cockerill, Natzi Sakalihasan, J.L. Martin-Ventura, Jean-Baptiste Michel, Vladislav Treska, Jesús Egido, Jesper Swedenborg, Unnur Thorsteinsdottir, Jes S. Lindholt, Eric Allaire

Publikováno v: Cardiovascular Research
Michel, J-B, Martin-Ventura, J-L, Egido, J, Sakalihasan, N, Treska, V, Lindholt, J S, Allaire, E, Thorsteinsdottir, U, Cockerill, G, Swedenborg, J & For the FAD EU consortium 2011, ' Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans ', Cardiovascular Research, vol. 90, no. 1, pp. 18-27 . https://doi.org/10.1093/cvr/cvq337
Cardiovascular Research; Vol 90

Aneurysm of the abdominal aorta (AAA) is a particular, specifically localized form of atherothrombosis, providing a unique human model of this disease. The pathogenesis of AAA is characterized by a breakdown of the extracellular matrix due to an exce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199c7e0c715e814b9c5c7a1d206258f5
http://europepmc.org/articles/PMC3058728