Twinning to reduce research and innovation inequalities in paediatric solid tumours across Europe

Autor: Jelena Rascon, Renata Blackute, Alma Cerkauskiene, Sabine Taschner-Mandl, Nuno Andrade, Adriana Planinic, Stefan Rutkowski, Ulrich Schuller, Karsten Nysom, Ruta Tuckuviene, Jesper Brok, Kjeld Schmiegelow, Marry M. van den Heuvel-Eibrink, M.E. Madeleine van der Perk, Riccardo Haupt, Monica Muraca, Davide Saraceno, Birgit Geoerger, Giorgia Manuzi, Ruth Ladenstein

Publikováno v: EJC Paediatric Oncology, Vol 3, Iss , Pp 100153- (2024)

Inequalities in research and innovations affect childhood cancer survival across Europe. Vilnius University Hospital Santaros Klinikos (VULSK, the coordinator) and eight research-intensive institutions from seven European countries implemented the TR

Externí odkaz: https://doaj.org/article/60514195038c4ebba5a83f379381f1cc

International Comparisons of Clinical Demographics and Outcomes in the International Society of Pediatric Oncology Wilms Tumor 2001 Trial and Study

Autor: Joaquim Caetano de Aguirre-Neto, Beatriz de Camargo, Harm van Tinteren, Christophe Bergeron, Jesper Brok, Gema Ramírez-Villar, Arnauld Verschuur, Rhoikos Furtwängler, Lisa Howell, Daniel Saunders, Oystein Olsen, Aurore Coulomb, Christian Vokuhl, Jan Godzinski, Anne M. Smets, Gordan M. Vujanic, Marry M. van den Heuvel-Eibrink, Norbert Graf, Kathy Pritchard-Jones

Publikováno v: JCO Global Oncology, Vol , Iss 8 (2022)

PURPOSEInternational comparisons of patient demographics, tumor characteristics, and survival can shed light on areas for health care system improvement. The International Society of Pediatric Oncology Wilms Tumor 2001 trial/study registered patients

Externí odkaz: https://doaj.org/article/99696dcdb6ec4ea5ac655aeb860d6c06

Somatic TP53 Mutations Are Detectable in Circulating Tumor DNA from Children with Anaplastic Wilms Tumors

Autor: Taryn D. Treger, Tasnim Chagtai, Robert Butcher, George D. Cresswell, Reem Al-Saadi, Jesper Brok, Richard D. Williams, Chrissy Roberts, Nicholas M. Luscombe, Kathy Pritchard Jones, William Mifsud

Publikováno v: Translational Oncology, Vol 11, Iss 6, Pp 1301-1306 (2018)

BACKGROUND: Diffuse anaplastic Wilms tumor (DAWT) is a rare, high-risk subtype that is often missed on diagnostic needle biopsy. Somatic mutations in TP53 are associated with the development of anaplasia and with poorer survival, particularly in adva

Externí odkaz: https://doaj.org/article/91db7bd722744d7e9972c46a34a8b83c

Essential medicines for childhood cancer in Europe: a pan-European, systematic analysis by SIOPE

Autor: Maria Otth, Eva Brack, Pamela R Kearns, Olga Kozhaeva, Marko Ocokoljic, Reineke A Schoot, Gilles Vassal, Federica Achini, Adriana Balduzzi, Maja Beck Popovic, Auke Beishuizen, Luca Bergamaschi, Andrea Biondi, Franck Bourdeaut, Elena Braicu, Jesper Brok, Laurence Brugières, Amos Burke, Gabriele Calaminus, Michela Casanova, Marie-Louise Choucair, Morgane Cleirec, Selim Corbaciouglu, Maria Genoveva Correa Llano, Teresa De Rojas, Nerea Domínguez Pinilla, Caroline Elmaraghi, Andrea Ferrari, Alexander Fossa, Nathalie Gaspar, Nikolas Herold, Kyriaki Karapiperi, Maarja Karu, Mimi Kjærsgaar, Fabian Knörr, Christa Koenig, Izabela Kranjcec, Malgorzata Krawczyk, Kai Lehmberg, Thomas Lehrnbecher, Maaike Lunesink, Davide Massano, Nuša Matijasic, Hans Merks, Markus Metzler, Anthony Michalski, Milen Minkov, Bruce Morland, Naghmeh Niktoreh, Elena Oltenau, Daniel Orbach, Cormac Owens, Smaragda Papachristidou, Claudia Pasqualini, Maja Pavlovic, Paula Perez Albert, Fiona Poyer, Ivana Radulovic, Dirk Reinhardt, Joana Rebelo, Eva Roser, Ida Russo, Katrin Scheinemann, Christina Schindera, Martin Schrappe, Astrid Sehested, Jalid Sehouli, Filippo Spreafico, Sandra J Strauss, Janine Stutterheim, Karel Svojgr, Vasiliki Tzotzola, Roelof Van Ewijk, Arnauld Verschuur, Ajay Vora, Willi Woessmann, Olga Zajac-Spychala, Michel Zwaan

Publikováno v: The Lancet Oncology. 23:1537-1546

Background: Shortages and unequal access to anticancer medicines for children and adolescents are a reality in Europe. The aim of the European Society for Paediatric Oncology (SIOPE) Essential Anticancer Medicines Project was to provide a list of ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa043c7d985289504ee8dd28c16211c
https://doi.org/10.1016/s1470-2045(22)00623-4

Surgical management, staging, and outcomes of Wilms tumours with intravascular extension: Results of the IMPORT study

Autor: Minou Oostveen, Tanzina Chowdhury, Imran Mushtaq, Øystein E. Olsen, Suzanne Tugnait, Tom A. Watson, Mark Powis, Sabine Irtan, Kristina Dzhuma, Naima Smeulders, Richard A Williams, Gordan M. Vujanic, Jesper Brok, Reem Al-Saadi, Kathy Pritchard-Jones, Susan C. Shelmerdine

Publikováno v: Journal of Pediatric Surgery. 57:572-578

To review surgical management, tumour stage and clinical outcomes in children with intravascular extension of Wilms tumour (WT) registered in a national clinical study (2012-19).WTs with presence/suspicion of tumour thrombus in the renal vein (RV) or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec1561f19dd7eab2cca652c506c65f1
https://doi.org/10.1016/j.jpedsurg.2021.08.023