Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jesko Kaiser"'
Autor:
Ying Gao, Marian Frank, Nicole Teusch, Dennis Woschko, Christoph Janiak, Attila Mándi, Tibor Kurtán, Rudolf Hartmann, Katja Schiedlauske, Lasse van Geelen, Rainer Kalscheuer, Jesko Kaiser, Christoph G. W. Gertzen, Holger Gohlke, Bin-Gui Wang, Peter Proksch, Zhen Liu
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Three sulfur-containing alkaloids aplospojaveedins A–C (1–3) with a hitherto undescribed carbon skeleton comprising octahy-dronaphthalene, α, β-unsaturated lactam and glycine-cysteine moieties were isolated from Aplosporella javeedii. Their str
Externí odkaz:
https://doaj.org/article/cb0d8e5ca85a405883d413726ab9f086
Autor:
Chaohui Lin, Edmund Osei Kuffour, Taolan Li, Christoph G. W. Gertzen, Jesko Kaiser, Tom Luedde, Renate König, Holger Gohlke, Carsten Münk
Publikováno v:
Viruses, Vol 16, Iss 4, p 485 (2024)
The innate immune response to viruses is formed in part by interferon (IFN)-induced restriction factors, including ISG15, p21, and SAMHD1. IFN production can be blocked by the ISG15-specific protease USP18. HIV-1 has evolved to circumvent host immune
Externí odkaz:
https://doaj.org/article/d61ad8202dbc47cdb8a67919f391ea8f
Autor:
Chaohui Lin, Edmund Osei Kuffour, Nina V. Fuchs, Christoph G.W. Gertzen, Jesko Kaiser, Maximilian Hirschenberger, Xiao Tang, Haifeng C. Xu, Oliver Michel, Ronny Tao, Alexandra Haase, Ulrich Martin, Thomas Kurz, Ingo Drexler, Boris Görg, Philipp A. Lang, Tom Luedde, Konstantin M.J. Sparrer, Holger Gohlke, Renate König, Carsten Münk
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113277- (2023)
Summary: Sensing of human immunodeficiency virus type 1 (HIV-1) DNA is mediated by the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling axis. Signal transduction and regulation of this cascade is achieved by post-translat
Externí odkaz:
https://doaj.org/article/a3e194c999a94c19ad46494fc14d84d4
Autor:
Jesko, Kaiser, Christoph G W, Gertzen, Tamara, Bernauer, Georg, Höfner, Karin V, Niessen, Thomas, Seeger, Franz F, Paintner, Klaus T, Wanner, Franz, Worek, Horst, Thiermann, Holger, Gohlke
Publikováno v:
Toxicology letters 373, 160-171 (2023). doi:10.1016/j.toxlet.2022.11.018
Organophosphorus compounds (OPCs) are highly toxic compounds that can block acetylcholine esterase (AChE) and thereby indirectly lead to an overstimulation of muscarinic and nicotinic acetylcholine receptors (nAChRs). The current treatment with atrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c056c65c6620869a66eab64752706a2
https://hdl.handle.net/2128/32994
https://hdl.handle.net/2128/32994
Autor:
Thomas Pauly, Najoua Bolakhrif, Jesko Kaiser, Luitgard Nagel-Steger, Lothar Gremer, Holger Gohlke, Dieter Willbold
Publikováno v:
The journal of biological chemistry 298(10), 102430 (2022). doi:10.1016/j.jbc.2022.102430
Methionine/valine polymorphism at position 129 of the human prion protein, huPrP, is tightly associated with the pathogenic phenotype, disease progress, and age of onset of neurodegenerative diseases such as Creutzfeldt-Jakob disease or Fatal Familia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4b09108fb7690b0ea6d8944cd57f8d
https://hdl.handle.net/2128/31900
https://hdl.handle.net/2128/31900