Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jesintha Gaston"'
Autor:
Daria Kartasheva-Ebertz, Jesintha Gaston, Loriane Lair-Mehiri, Estelle Mottez, Tan-Phuc Buivan, Pierre-Philippe Massault, Olivier Scatton, Sebastien Gaujoux, Jean-Christophe Vaillant, Stanislas Pol, Sylvie Lagaye
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9773 (2022)
IL-17A is considered to guide liver inflammation and fibrosis. From twenty-two human liver samples of different fibrosis stages (F0 to F4), IL-17A, IL-22, and TGFβ1 protein expression in liver tissue lysates were analyzed. Ten paired samples of live
Externí odkaz:
https://doaj.org/article/13e744ab665d4aafb2626c08cd3b787a
Autor:
Lynda Aoudjehane, Grégoire Bisch, Olivier Scatton, Christelle Granier, Jesintha Gaston, Chantal Housset, Philippe Roingeard, François-Loïc Cosset, Fabiano Perdigao, Pierre Balladur, Takaji Wakita, Yvon Calmus, Filomena Conti
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134141 (2015)
Chronic hepatitis C is a major cause of liver fibrosis and cirrhosis. It is generally accepted that inflammation that occurs in response to hepatocyte infection by the hepatitis C virus (HCV) is the main mechanism that triggers myofibroblast differen
Externí odkaz:
https://doaj.org/article/c3c91e32fd9d4b0d8bf4b8df03224cbe
Autor:
Olivier Scatton, Loriane Lair-Mehiri, Sylvie Lagaye, Jesintha Gaston, Jean-Christophe Vaillant, Vladimir A. Morozov, Pierre-Philippe Massault, Daria Kartasheva-Ebertz, Stanislas Pol
Publikováno v:
World Journal of Hepatology
World journal of hepatology
World journal of hepatology, 2021, World Journal of Hepatology, 13 (2), pp.187-217. ⟨10.4254/wjh.v13.i2.187⟩
World journal of hepatology, Baishideng Publishing Group Inc, 2021, World Journal of Hepatology, 13 (2), pp.187-217. ⟨10.4254/wjh.v13.i2.187⟩
World journal of hepatology
World journal of hepatology, 2021, World Journal of Hepatology, 13 (2), pp.187-217. ⟨10.4254/wjh.v13.i2.187⟩
World journal of hepatology, Baishideng Publishing Group Inc, 2021, World Journal of Hepatology, 13 (2), pp.187-217. ⟨10.4254/wjh.v13.i2.187⟩
International audience; BACKGROUNDLiver fibrosis can result in end-stage liver failure and death.AIMTo examine human liver fibrogenesis and anti-fibrotic therapies, we evaluated the three dimensional ex vivo liver slice (LS) model.METHODSFibrotic liv
Autor:
Jesintha Gaston, Jean-Christophe Vaillant, P. Stanislas, Sylvie Lagaye, Vladimir A. Morozov, Olivier Scatton, D. Kartasheva
Publikováno v:
Journal of Hepatology. 68:S405-S406
Autor:
Michelina Nascimbeni, Laurent Hannoun, Hong Shen, Sylvie Lagaye, Stanislas Pol, Bertrand Saunier, Jesintha Gaston, Pierre Bourdoncle, Anaïs Vallet-Pichard, Vincent Mallet, Pierre-Philippe Massault
Publikováno v:
Hepatology. 56:861-872
The development of human cultured hepatitis C virus (HCV) replication-permissive hepatocarcinoma cell lines has provided important new virological tools to study the mechanisms of HCV infection; however, this experimental model remains distantly rela
Autor:
Annick Vieillefond, Estelle Ferries, Francine Connan, Franck Pagès, Jesintha Gaston, Anne-Marie Hagnéré, Nicolas Thiounn, Jean-Gérard Guillet, Jeannine Choppin
Publikováno v:
Human Immunology. 62:791-798
In many types of cancer, p53 frequently accumulates in tumor cells and anti-p53 antibodies can be detected. However, only four CD8+ T-cell epitopes from p53 have been identified in humans so far. To further analyze the development of a T-cell respons
Autor:
Loubna Erraji, Jesintha Gaston, Paule Varlet, Jean-Gérard Guillet, Claudine André, Dominique Couton, Laurent Rénia, Pascale Briand
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 276:G647-G654
Stimulation of the cAMP-signaling pathway modulates apoptosis in several cell types and inhibits Jo2-mediated apoptosis in cultured rat hepatocytes. No information is yet available as to whether the hepatic β2-adrenergic receptor (AR) expression lev
Autor:
Gisèle Grimber, Jesintha Gaston, Pascale Briand, Claudine André, Loubna Erraji, Jean-Gérard Guillet
Publikováno v:
European Journal of Biochemistry. 241:417-424
Up to now, transgenic mice models created to study the physiological impact of alterations in the human beta-adrenoceptor system have only focused on cardiac tissues and carried hybrid transgenes with strong cardiac promoters. We have developed a tra
Autor:
P.-P. Massault, Stanislas Pol, Jean-Christophe Vaillant, Sylvie Lagaye, J. Guéchot, Jesintha Gaston
Publikováno v:
Journal of Hepatology. 64:S187
Autor:
Hong Shen, Sylvie Lagaye, Ruzena Wiersum Stranska, Claire Camus, Philippe Halfon, Firas Bassisi, Jesintha Gaston, Jérôme Courcambeck, Clarisse Dubray, Géraldine Rousseau, Sonia Brun, Stanislas Pol, Pierre-Philippe Massault
Publikováno v:
World Journal of Hepatology
AIM: To evaluate the antiviral potency of a new anti-hepatitis C virus (HCV) antiviral agent targeting the cellular autophagy machinery. METHODS: Non-infected liver slices, obtained from human liver resection and cut in 350 μm-thick slices (2.7 × 1