Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Jesang Ko"'
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e29292- (2024)
Angiogenesis is an indispensable mechanism in cancer progression, as cancer cells need to establish blood vessels to supply oxygen and nutrients. Extracellular vesicles (EVs) derived from cancer cells act as messengers in the tumor microenvironment a
Externí odkaz:
https://doaj.org/article/e9abe15d9af149e188df44eceed0b69d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The first-line treatment for prostate cancer (PCa) is androgen ablation therapy. However, prostate tumors generally recur and progress to androgen-independent PCa (AIPC) within 2–3 years. α-Actinin-4 (ACTN4) is an actin-binding protein that belong
Externí odkaz:
https://doaj.org/article/c67782f435d2486b8926b6af3c04a912
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180197 (2017)
The nuclear transcription factor estrogen receptor α (ERα) plays a critical role in breast cancer progression. ERα acts as an important growth stimulatory protein in breast cancer and the expression level of ERα is tightly related to the prognosi
Externí odkaz:
https://doaj.org/article/940e22d907664399be0231b298294b90
Publikováno v:
Cellular Physiology and Biochemistry, Vol 33, Iss 1, Pp 151-164 (2014)
Background/Aims: Matrix metalloproteinase-9 (MMP-9) plays an important role in tumor invasion and metastasis through the breakdown of extracellular matrix. The c-Jun protein, a major component of the AP-1 transcription factor, is elevated in various
Externí odkaz:
https://doaj.org/article/55cf917448584753824a85ecb38eff9d
Autor:
Ho Taek Oh, Woong Heo, Gi Don Yoo, Kyung Min Kim, Jun‐Ha Hwang, Eun Sook Hwang, Jesang Ko, Young‐Gyu Ko, Jeong‐Ho Hong
Publikováno v:
Journal of Cellular Physiology. 237:4504-4516
Chronic liver injury follows inflammation and liver fibrosis; however, the molecular mechanism underlying fibrosis has not been fully elucidated. In this study, the role of ductal WW domain-containing transcription regulator 1 (WWTR1)/transcriptional
Publikováno v:
Cellular and Molecular Life Sciences. 79
In multiple cancers, autophagy promotes tumor development by recycling intracellular components into metabolic pathways. Autophagy-induced metabolic reprogramming and plasticity lead to cancer cell survival and resistance to anticancer therapy. We in
Publikováno v:
Journal of Molecular Cell Biology
Hepatic gluconeogenesis is the central pathway for glucose generation in the body. The imbalance between glucose synthesis and uptake leads to metabolic diseases such as obesity, diabetes, and cardiovascular diseases. Small leucine zipper protein (sL
Publikováno v:
Carcinogenesis. 41:940-949
Cancer stem cells (CSCs) initiate tumors and possess the properties of self-renewal and differentiation. Since they are responsible for chemoresistance, CSCs are known to be a key factor in cancer recurrence. α-Actinin-4 (ACTN4) is an actin-binding
Publikováno v:
The FASEB Journal. 33:4248-4260
Extracellular vesicles contain various cellular components that are involved in tumor growth, metastasis, and immune escape. Extracellular vesicles are classified into 2 groups, namely, exosomes and microvesicles (MV). Although the formation and role
Publikováno v:
Carcinogenesis. 42(8)
Matrix metalloproteinases (MMPs) function as central modulators of tissue remodeling. Abnormal expression and altered activity of MMPs result in excessive extracellular matrix degradation and increased tumor metastasis in various cancers. Small leuci