Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Jesaia, Benhorin"'
Autor:
Jesaia Benhorin, Arthur J. Moss, Matthew Bak, Wojciech Zareba, Elizabeth S. Kaufman, Batsheva Kerem, Jeffrey A. Towbin, Silvia Priori, Robert S. Kass, Bernard Attali, Arthur M. Brown, Eckhard Ficker
Publikováno v:
Annals of Noninvasive Electrocardiology, Vol 7, Iss 1, Pp 40-46 (2001)
Objectives: This study assessed the phenotypic variability of LQTS in carriers with the same and with different mutations in the LQT2 gene. Background: Mutations of ion‐channel genes are known to cause the long QT syndrome (LQTS), a disorder associ
Externí odkaz:
https://doaj.org/article/48befc71b3f34de49c996b5276d68d7b
Publikováno v:
EP Europace. 20:370-376
Aims Type 3 long QT syndrome (LQT3) is caused by gain-of-function mutations in the cardiac sodium channel gene (SCN5A). Previous reports on the long-term use of sodium channel blockers in LQT3 are sparse. The objective of the current study was to eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504ecfda1cca9148dbcd60b45d4f1913
https://doi.org/10.1093/europace/euw439
https://doi.org/10.1093/europace/euw439
Autor:
Derick R. Peterson, Marielle Alders, Connie R. Bezzina, Wataru Shimizu, Takeshi Aiba, Michael J. Ackerman, Bronislava Polonsky, Coeli M. Lopes, Yoshihiro Miyamoto, Arthur J. Moss, David J. Tester, Jørgen K. Kanters, Carla Spazzolini, Jennifer L. Robinson, Ming Qi, Jeffrey A. Towbin, Arthur A.M. Wilde, Wojciech Zareba, Ilan Goldenberg, Elizabeth S. Kaufman, Jesaia Benhorin, Nynke Hofman, Mark L. Andrews, Lia Crotti, Peter J. Schwartz, Scott McNitt, Shiro Kamakura
Publikováno v:
Circulation, 134(12), 872-882. Lippincott Williams and Wilkins
Circulation 134, 872-882 (2016)
Circulation 134, 872-882 (2016)
Background: Risk stratification in patients with type 3 long-QT syndrome (LQT3) by clinical and genetic characteristics and effectiveness of β-blocker therapy has not been studied previously in a large LQT3 population. Methods: The study population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c9aa2626fd7ea9277fdd01b340ed43
https://doi.org/10.1161/circulationaha.116.021823
https://doi.org/10.1161/circulationaha.116.021823
Autor:
Arthur J. Moss, Jamie Mullally, Jennifer L. Robinson, Coeli M. Lopes, Ilan Goldenberg, Alon Barsheshet, Elizabeth S. Kaufman, Jesaia Benhorin, Scott McNitt, Jeffrey A. Towbin, Wojciech Zareba, Michael J. Ackerman
Publikováno v:
Heart Rhythm. 10:378-382
Background Patients with long QT syndrome (LQTS) who harbor multiple mutations (i.e. ≥ 2 mutations in ≥ 1 LQTS-susceptibility gene) may experience increased risk for life-threatening cardiac events. Objectives The present study was designed to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1928f5e14dd8863293902e9c1ca7bf
https://doi.org/10.1016/j.hrthm.2012.11.006
https://doi.org/10.1016/j.hrthm.2012.11.006
Autor:
Arthur A.M. Wilde, Jeffrey A. Towbin, Arthur J. Moss, Emanuela H. Locati, G. Michael Vincent, Scott McNitt, Michael J. Ackerman, Jesaia Benhorin, Ilan Goldenberg, Alon Barsheshet, Ming Qi, Elizabeth S. Kaufman, Pyotr G. Platonov, Andrew Mathias, Li Zhang, Coeli M. Lopes, Jennifer L. Robinson, Wojciech Zareba, Wataru Shimizu
Publikováno v:
Heart rhythm, 10(5), 720-725. Elsevier
Individual corrected QT interval (QTc) may vary widely among carriers of the same long QT syndrome (LQTS) mutation. Currently, neither the mechanism nor the implications of this variable penetrance are well understood. To hypothesize that the assessm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9616f4124ae2de65a41ba4d8c9787e
https://doi.org/10.1016/j.hrthm.2013.01.032
https://doi.org/10.1016/j.hrthm.2013.01.032
Autor:
Charles Antzelevitch, David Zeltser, Jesaia Benhorin, Sami Viskin, Aviram Hochstadt, Raphael Rosso, Hector Barajas-Martinez, Uri Rozovski, Dan Hu, Ehud Chorin, Arnon Adler, Luiz Belardinelli
Publikováno v:
Circulation: Arrhythmia and Electrophysiology. 9
Background— The basic defect in long-QT syndrome type III (LQT3) is an excessive inflow of sodium current during phase 3 of the action potential caused by mutations in the SCN5A gene. Most sodium channel blockers reduce the early (peak) and late co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7754fc4862e4f20f5929cc80f5cfacc9
https://doi.org/10.1161/circep.116.004370
https://doi.org/10.1161/circep.116.004370
Autor:
Charles Antzelevitch, Amir Halkin, Raphael Rosso, Jitendra K. Vohra, Arnon Adler, Sami Viskin, Pieter G. Postema, Arthur A.M. Wilde, Manlio F. Márquez, Christian van der Werf, Zahir A. Bhuiyan, Jonathan M. Kalman, Jesaia Benhorin, Milton E Guevara-Valdivia
Publikováno v:
Heart rhythm, 9(6), 901-908. Elsevier
BACKGROUND Patients with long QT syndrome (LQTS) have inadequate shortening of the QT interval in response to the sudden heart rate accelerations provoked by standing-a phenomenon of diagnostic value. We now validate our original observations in a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f64279cdd210361f752b136efc6307
https://doi.org/10.1016/j.hrthm.2012.01.026
https://doi.org/10.1016/j.hrthm.2012.01.026
Autor:
Jennifer L. Robinson, Coeli M. Lopes, Ming Qi, Michael J. Ackerman, Scott McNitt, Arthur J. Moss, Slava Polonsky, Wojciech Zareba, Jeffrey A. Towbin, G. Michael Vincent, Ilan Goldenberg, Alon Barsheshet, Elizabeth S. Kaufman, Jesaia Benhorin
Publikováno v:
Circulation: Cardiovascular Genetics. 4:491-499
Background— Current clinical diagnosis of long-QT syndrome (LQTS) includes genetic testing of family members of mutation-positive patients. The present study was designed to assess the clinical course of individuals who are found negative for the L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2217f7f50e5022511c7b13b23b2c10f5
https://doi.org/10.1161/circgenetics.111.960179
https://doi.org/10.1161/circgenetics.111.960179
Autor:
Michael J. Ackerman, Derick R. Peterson, G. Michael Vincent, Jesaia Benhorin, Arthur J. Moss, Peter J. Schwartz, Ilan Goldenberg, Alon Barsheshet, Li Zhang, Elizabeth S. Kaufman, Jeffrey A. Towbin, Jennifer L. Robinson, Scott McNitt, Wojciech Zareba, Jonathan Buber, Slava Polonsky
Publikováno v:
Heart Rhythm. 8:1207-1213
Background A prolonged QT interval corrected for heart rate (QTc) is a major risk factor in patients with long QT syndrome (LQTS). However, heart rate–related risk in this genetic disorder differs among genotypes. Objective This study hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4348596f88a872c72254be0b27efe37c
https://doi.org/10.1016/j.hrthm.2011.03.009
https://doi.org/10.1016/j.hrthm.2011.03.009
Autor:
Emanuela H. Locati, Peter J. Schwartz, Ming Qi, Scott McNitt, Michael J. Ackerman, Carlo Napolitano, Silvia G. Priori, Judy F. Liu, Jesaia Benhorin, Michael Vincent, Derick R. Peterson, Jeffrey A. Towbin, Arthur J. Moss, Ilan Goldenberg, Alon Barsheshet, Wojciech Zareba, Elizabeth S. Kaufman, Jennifer L. Robinson, Li Zhang, Christian Jons
Publikováno v:
Journal of the American College of Cardiology. 57(8):941-950
ObjectivesWe aimed to identify risk factors for recurrent syncope in children and adolescents with congenital long QT syndrome (LQTS).BackgroundData regarding risk assessment in LQTS after the occurrence of the first syncope episode are limited.Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c455d6075d2587e9a8af12232aea8d