Factor Xa and VIIa inhibition by tissue factor pathway inhibitor is prevented by a monoclonal antibody to its Kunitz-1 domain

Autor: X. Wenjuan, Lars Christian Petersen, Cecilia Augustsson, Anders Svensson, Tzu-Yuan Chao, Jens Breinholt, Jes Thorn Clausen, Helle Heibroch Petersen, Berit Olsen Krogh, B. Kjær, Ida Hilden

Publikováno v: Journal of thrombosis and haemostasis : JTH. 16(5)

Essentials Activated FVII (FVIIa) and FX (FXa) are inhibited by tissue factor pathway inhibitor (TFPI). A monoclonal antibody, mAb2F22, was raised against the N-terminal fragment of TFPI (1-79). mAb2F22 bound exclusively to the K1 domain of TFPI (KD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047a540e27d8aef619a639fab19eebba
https://pubmed.ncbi.nlm.nih.gov/29532595

Importance of Cocaine- and Amphetamine-Regulated Transcript Peptide in the Central Nucleus of Amygdala in Anxiogenic Responses Induced by Ethanol Withdrawal

Autor: Dadasaheb M. Kokare, Ronald M. Lechan, Nishikant K. Subhedar, Jes Thorn Clausen, Lars Thim, Praful S. Singru, Manoj P. Dandekar

Publikováno v: Neuropsychopharmacology. 33:1127-1136

We studied the involvement of cocaine- and amphetamine-regulated transcript peptide (CART) in the central nucleus of amygdala (CeA), lateral bed nucleus of the stria terminalis (BNSTl) and nucleus accumbens shell (AcbSh) in generation of ethanol with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2005e36a4907829209f03ae8c10f831
https://doi.org/10.1038/sj.npp.1301516

Epidermal Overexpression of Interleukin-19 and -20 mRNA in Psoriatic Skin Disappears After Short-Term Treatment with Cyclosporine A or Calcipotriol

Autor: Peder Lisby Nørby, Knud Kragballe, John Rømer, Erik Hasselager, Torben Steiniche, Jes Thorn Clausen

Publikováno v: Journal of Investigative Dermatology. 121:1306-1311

Interleukin-19, 20, and 24 are new members of the IL-10 family binding and signaling through the IL-20R1/IL-20R2 heterodimer, while IL-20 and 24 also bind to the IL-20R2/IL-22R1 heterodimer. Using in situ hybridization we have studied mRNA expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53df6d0f3b148d6e9b207a4e5bdf57e
https://doi.org/10.1111/j.1523-1747.2003.12626.x

Cocaine- and amphetamine-regulated transcript peptide (CART) in the telencephalon of the catfish, Clarias gariepinus: distribution and response to fasting, 2-deoxy-D-glucose, glucose, insulin, and leptin treatments

Autor: Praful S. Singru, Vikas G. Barsagade, Lars Thim, Jes Thorn Clausen, Nishikant K. Subhedar

Publikováno v: The Journal of comparative neurology. 519(7)

The cocaine- and amphetamine-regulated transcript peptide (CART)-containing system in the forebrain of Clarias gariepinus was studied with immunocytochemistry. While the immunoreactivity was prominently seen in the neurons of the entopeduncular nucle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5389a05fe78ee10484d67ba2d11efe25
https://pubmed.ncbi.nlm.nih.gov/21452197

Interleukin-20 plays a critical role in maintenance and development of psoriasis in the human xenograft transplantation model

Autor: Lars Fogh Iversen, Cecilia Rosada, Torben Steiniche, Frederik Dagnæs-Hansen, Anne Worsaae, Knud Kragballe, Karin Stenderup, H. Lindgreen Holmberg, H. Wöldike, John Rømer, S. Zahn, Tomas Norman Dam, Erik Hasselager, Jes Thorn Clausen

Publikováno v: Stenderup, K, Rosada, C, Worsaae, A, Dagnaes-Hansen, F, Steiniche, T, Hasselager, E, Iversen, L F, Zahn, S, Wöldike, H, Lindgreen Holmberg, H, Rømer, J, Kragballe, K, Clausen, J T & Dam, T N 2009, ' Interleukin-20 plays a critical role in maintenance and development of psoriasis in the human xenograft transplantation model ', British Journal of Dermatology, vol. 160, no. 2, pp. 284-296 . https://doi.org/10.1111/j.1365-2133.2008.08890.x
Stenderup, K, Rosada, C, Worsaae, A, Dagnaes-Hansen, F, Steiniche, T, Hasselager, E, Iversen, L, Zahn, S, Wöldike, H, Holmberg, H L, Rømer, J, Kragballe, K, Clausen, J T & Dam, T N 2008, ' Interleukin-20 plays a critical role in maintenance and development of psoriasis in the human xenograft transplantation model ', British Journal of Dermatology, vol. 160, no. 2, pp. 284-96 . https://doi.org/10.1111/j.1365-2133.2008.08890.x

Udgivelsesdato: 2009-Feb BACKGROUND: Interleukin (IL)-20 is a recently discovered cytokine displaying increased levels in psoriatic lesions. Interestingly, IL-20 levels decrease with antipsoriatic treatment, correlating with clinical improvement. How

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54eb45bd423bf42a47febbe50c752482
https://portal.findresearcher.sdu.dk/da/publications/18f5e170-bd30-11dd-9b31-000ea68e967b