Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling

Autor: Martti Maimets, Marianne Terndrup Pedersen, Jordi Guiu, Jes Dreier, Malte Thodberg, Yasuko Antoku, Pawel J. Schweiger, Leonor Rib, Raul Bardini Bressan, Yi Miao, K. Christopher Garcia, Albin Sandelin, Palle Serup, Kim B. Jensen

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

The small intestine forms via crosstalk between epithelial and mesenchymal cell compartments. Here, the authors show that a gradient of Wnt signalling along the anterior-posterior axis regulates Sonic Hedgehog which is required for correct formation

Externí odkaz: https://doaj.org/article/f98ce2e90f0a4e679e2e55251af11038

Accelerated redevelopment of vocal skills is preceded by lasting reorganization of the song motor circuitry

Autor: Michiel Vellema, Mariana Diales Rocha, Sabrina Bascones, Sándor Zsebők, Jes Dreier, Stefan Leitner, Annemie Van der Linden, Jonathan Brewer, Manfred Gahr

Publikováno v: eLife, Vol 8 (2019)

Complex motor skills take considerable time and practice to learn. Without continued practice the level of skill performance quickly degrades, posing a problem for the timely utilization of skilled motor behaviors. Here we quantified the recurring de

Externí odkaz: https://doaj.org/article/3ecd3377b8304888926aa14775542179

Forces drive basement membrane invasion in Caenorhabditis elegans

Autor: Laura C. Kelley, Qiuyi Chi, David R. Sherwood, Thomas Risler, Nagagireesh Bojanala, Ilaria Testa, Julie Plastino, Fahima Di Federico, John Manzi, Rodrigo Cáceres, Jes Dreier

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (45), pp.11537-11542. ⟨10.1073/pnas.1808760115⟩

Significance Basement membrane is a particular kind of sheet-like extracellular matrix that separates tissue compartments. Invasion of cells through basement membrane barriers is a key aspect of many normal and pathological processes, including organ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a29aa2e8ebc21de650a72b28326a02
https://doi.org/10.1073/pnas.1808760115

The nanoscopic molecular pathway through human skin

Autor: Jonathan R. Brewer, I.E. Antonescu, Irina Iachina, Jens Ahm Sørensen, Jes Dreier

Publikováno v: Iachina, I, Antonescu, I E, Dreier, J, Sørensen, J A & Brewer, J R 2019, ' The nanoscopic molecular pathway through human skin ', B B A-General Subjects, vol. 1863, no. 7, pp. 1226-1233 . https://doi.org/10.1016/j.bbagen.2019.04.012
Iachina, I, Antonescu, I E, Dreier, J, Sørensen, J A & Brewer, J R 2019, ' The nanoscopic molecular pathway through human skin ', Biochimica et Biophysica Acta-General Subjects, vol. 1863, no. 7, pp. 1226-1233 . https://doi.org/10.1016/j.bbagen.2019.04.012

Background Knowledge regarding the barrier properties of human skin is important for understanding skin pathology, developing of transdermal drug delivery systems and computational skin absorption models; however, the molecular pathways through human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d178841b39d95613a9b3f28e1ca94e7
https://curis.ku.dk/ws/files/252149809/The_nanoscopic_molecular_pathway_through_human_skin_Acc._Manuscript_.pdf

Vocal motor experiences consolidate the vocal motor circuitry and accelerate future vocal skill development

Autor: Michiel Vellema, Annemie Van der Linden, Sabrina Bascones, Stefan Leitner, Manfred Gahr, Mariana Diales da Rocha, Jes Dreier, Sándor Zsebők, Jonathan R. Brewer

Publikováno v: bioRxiv

Complex motor skills take considerable time and practice to learn. Without continued practice the level of skill performance quickly degrades, posing a problem for the timely utilization of skilled motor responses. Here we quantified the recurring de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2c535de1d022dd155611bb87ab7941