Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jesús Servando Medel‐Matus"'
Publikováno v:
Epilepsia Open, Vol 7, Iss S1, Pp S81-S93 (2022)
Abstract In basic research and clinical practice, the control of seizures has been the most important goal, but it should not be the only one. There are factors that remain poorly understood in the study of refractory epilepsy such as the age and gen
Externí odkaz:
https://doaj.org/article/3e8339c0e7e242f4a5ab83d873ae40d5
Publikováno v:
Epilepsia. 62:1472-1481
Objective Traumatic brain injury (TBI) may lead to the disruption of the intestinal barrier (IB), and to the escape of products of commensal gut bacteria, including lipopolysaccharide (LPS), into the bloodstream. We examined whether lateral fluid per
Publikováno v:
Epilepsia Open
Epilepsia Open, Vol 6, Iss 2, Pp 413-418 (2021)
Epilepsia open, vol 6, iss 2
Epilepsia Open, Vol 6, Iss 2, Pp 413-418 (2021)
Epilepsia open, vol 6, iss 2
Lateral fluid percussion injury (LFPI) in rats is used to model post-traumatic epilepsy (PTE), with spontaneous seizures occurring in up to ½ of the subjects. Using the kindling paradigm, we examined whether animals without detectable seizures had a
Publikováno v:
Seizure. 90
Traumatic brain injury (TBI) is defined as a disturbance in brain functioning caused by an external force. The development of post traumatic epilepsy (PTE) is a serious risk associated with TBI. Indeed, other neurological impairments are also common
Autor:
Maria-Leonor Lopez-Meraz, Jesús-Servando Medel-Matus, Juan Francisco Rodríguez-Landa, C. Rincón-López, J. Martínez-Quiroz, A. Tlapa-Pale
Publikováno v:
Neurología (English Edition), Vol 32, Iss 9, Pp 587-594 (2017)
Background: Interleukin-1β (IL-1β) increases necrotic neuronal cell death in the CA1 area after induced status epilepticus (SE) in developing rats. However, it remains uncertain whether IL-1β has a similar effect on the hippocampal dentate gyrus (
Publikováno v:
Epilepsia. 58:e122-e126
This study examined whether toll-like receptors 2 (TLR2) contribute to the rapid kindling epileptogenesis. A TLR2 agonist, lipoteichoic acid (LTA), LTA antibody (LTA-A) or normal saline (control) were administered daily over three consecutive days, u
Autor:
Jesús-Servando Medel-Matus, Elena Minakova, Andrey Mazarati, Ashley Reynolds, Georgianna G. Gould, Jordan Lang, Raman Sankar, Don Shin
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210389 (2019)
PLoS ONE
PloS one, vol 14, iss 1
PLoS ONE
PloS one, vol 14, iss 1
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impaired social interactions, difficulty with communication, and repetitive behavior patterns. In humans affected by ASD, there is a male pre-disposition towards
Autor:
Pierre-Pascal Lenck-Santini, Jana Velíšková, Aristea S. Galanopoulou, Lauren C. Harte-Hargrove, Liset Menendez de la Prida, Astrid Nehlig, Nigel C. Jones, Lisa E. Kalynchuk, Andrey Mazarati, Jesús-Servando Medel-Matus, Karine Sarkisova
Publikováno v:
Epilepsia open, vol 3, iss Suppl Suppl 1
Epilepsia Open
Epilepsia Open, 2018, 3, pp.24-52. ⟨10.1002/epi4.12236⟩
Epilepsia Open, The International League Against Epilepsy 2018, 3, pp.24-52. ⟨10.1002/epi4.12236⟩
Epilepsia Open
Epilepsia Open, 2018, 3, pp.24-52. ⟨10.1002/epi4.12236⟩
Epilepsia Open, The International League Against Epilepsy 2018, 3, pp.24-52. ⟨10.1002/epi4.12236⟩
International audience; The provided companion has been developed by the Behavioral Working Group of the Joint Translational Task Force of the International League Against Epilepsy (ILAE) and the American Epilepsy Society (AES) with the purpose of as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99980f9fad6385b46ce7ab36ad225cf
https://escholarship.org/uc/item/5r70s8f7
https://escholarship.org/uc/item/5r70s8f7
Publikováno v:
Epilepsia open, vol 3, iss 2
Epilepsia Open
Epilepsia Open
Summary There has been growing interest in the role of intestinal microbiome in brain disorders. We examined whether dysbiosis can predispose to epilepsy. The study was performed in female and male Sprague‐Dawley rats. To induce dysbiosis, the rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d1233a2db0e4d3693ace901474388b
https://escholarship.org/uc/item/8526b19h
https://escholarship.org/uc/item/8526b19h
Autor:
James Washington, Raman Sankar, Don Shin, Udaya Kumar, Jesús-Servando Medel-Matus, Andrey Mazarati
Publikováno v:
Epilepsy & Behavior. 50:40-45
Maternal immune activation (MIA) results in the development of autism in the offspring via hyperactivation of IL-6 signaling. Furthermore, experimental studies showed that the MIA-associated activation of interleukin-1β (IL-1β) concurrently with IL