Výsledky vyhledávání - "Jesús R Morales"

Validation of housekeeping genes for quantitative real-time PCR in in-vivo and in-vitro models of cerebral ischaemia

Autor: Joaquín Serena, María A. Moro, Víctor G. Romera, Judith Mallolas, Olivia Hurtado, Carme Gubern, Ignacio Lizasoain, Jesús R Morales, Rocío Rodríguez

Publikováno v: BMC Molecular Biology, 2009, vol. 16, núm. 10, p. 57
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BMC Molecular Biology, Vol 10, Iss 1, p 57 (2009)
BMC Molecular Biology

Background Studies of gene expression in experimental cerebral ischaemia models can contribute to understanding the pathophysiology of brain ischaemia and to identifying prognostic markers and potential therapeutic targets. The normalization of relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03d9cb520c7f18fc50f00926daee94d
http://hdl.handle.net/10256/16458

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Activation of liver X receptors promotes neuroprotection and reduces brain inflammation in experimental stroke

Autor: Jose M. Déniz, Iván Ballesteros, Olivia Hurtado, José Vivancos, María A. Moro, Florentino Nombela, Ignacio Lizasoain, Jesús R Morales, Antonio Castrillo

Publikováno v: Circulation. 118(14)

Background— The liver X receptors (LXRs) belong to the nuclear receptor superfamily and act as transcriptional regulators of cholesterol metabolism in several tissues. Recent work also has identified LXRs as potent antiinflammatory molecules in mac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebdb93e051adc41985dec8d3c8b6f04
https://pubmed.ncbi.nlm.nih.gov/18794391

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Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection

Autor: Florentino Nombela, Judith Mallolas, Jesús R Morales, Pedro Lorenzo, Ignacio Lizasoain, José Vivancos, Olivia Hurtado, María A. Moro, Alejandro Romera, Marta P. Pereira, Cristina Romera, Joaquín Serena

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 27(7)

Excessive levels of extracellular glutamate in the nervous system are excitotoxic and lead to neuronal death. Glutamate transport, mainly by glutamate transporter GLT1/EAAT2, is the only mechanism for maintaining extracellular glutamate concentration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc04783db97b10ee1d0233be8208a18d
https://pubmed.ncbi.nlm.nih.gov/17213861

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A chronic treatment with CDP-choline improves functional recovery and increases neuronal plasticity after experimental stroke

Autor: María A. Moro, F. Ortego, Jesús M. Pradillo, Tomás Sobrino, Jesús R Morales, Ignacio Lizasoain, Olivia Hurtado, José Castillo, Antonio Cárdenas

Publikováno v: Neurobiology of Disease, Vol 26, Iss 1, Pp 105-111 (2007)

Chronic impairment of forelimb and digit movement is a common problem after stroke that is resistant to therapy. Although in the last years some studies have been performed to increase the efficacy of rehabilitative experience and training, the pharm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69dbbbf4b30841fb48157feef915b867
https://pubmed.ncbi.nlm.nih.gov/17234423

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