Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Jesús Planagumà"'
Autor:
Guillermo Muñoz-Sánchez, Jesús Planagumà, Laura Naranjo, Rocío Couso, Lidia Sabater, Mar Guasp, Eugenia Martínez-Hernández, Francesc Graus, Josep Dalmau, Raquel Ruiz-García
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Detection of Leucine-rich glioma inactivated 1 (LGI1) antibodies in patients with suspected autoimmune encephalitis is important for diagnostic confirmation and prompt implementation of immunomodulatory treatment. However, the clinical laboratory dia
Externí odkaz:
https://doaj.org/article/3d040088d69c41368250a0da1f770843
Autor:
Laurent Ladépêche, Jesús Planagumà, Shreyasi Thakur, Irina Suárez, Makoto Hara, Joseph Steven Borbely, Angel Sandoval, Lara Laparra-Cuervo, Josep Dalmau, Melike Lakadamyali
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3759-3768 (2018)
Summary: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric disorder mediated by autoantibodies against the GluN1 subunit of the NMDAR. Patients’ antibodies cause cross-linking and internalization of NMDAR, but the
Externí odkaz:
https://doaj.org/article/3c31c9ed99714849b9b82a738fa3e098
Autor:
Mar Guasp, Mireia Rosa-Justicia, Amaia Muñoz-Lopetegi, Eugenia Martínez-Hernández, Thais Armangué, Gisela Sugranyes, Heike Stein, Roger Borràs, Laia Prades, Helena Ariño, Jesús Planagumà, Elena De-La-Serna, Domingo Escudero, Sara Llufriu, Raquel Sánchez-Valle, Joan Santamaria, Albert Compte, Josefina Castro-Fornieles, Josep Dalmau, Dolores Páramo, Vicente Medrano, Virginia Casado, Nicolau Guanyabens, Eloi Giné-Servén, María Ángeles del Real, Javier Pardo, Leticia Martin-Gil, Francisco Javier Barrero-Hernández, Nuria García-Barragán, Mercè Falip, Marta Simó, Eloy Rodríguez, Juan José Ruiz Ezquerro, Luis Bataller, Gemma Safont, José Vicente-Hervàs, Luis Brieva, Ignacio Casado, Juan Carlos Portilla, Sònia Escalante, Juan Francisco Arenillas, Elena Erro, Ivonne Jericó-Pascual, Alejandro Fuerte-Hortigón, Alba Morató, Albert Saiz, Yolanda Blanco, Maria Sepúlveda, Raquel Ruiz, Laura Naranjo, Maria Rodés, Esther Aguilar, Mercè Alba, Eva Caballero
Publikováno v:
The Lancet Neurology. 21:899-910
Anti-NMDA receptor (NMDAR) encephalitis is associated with a post-acute stage that is not well known. We aimed to describe the clinical features of this stage, similarities with schizophrenia spectrum disorders, and the factors that predict cognitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3abd96ee25eb3efdaf2f3ba1b472596
https://doi.org/10.1016/s1474-4422(22)00299-x
https://doi.org/10.1016/s1474-4422(22)00299-x
Autor:
Mar Guasp, Mireia Rosa-Justicia, Amaia Muñoz-Lopetegi, Eugenia Martinez-Hernandez, Thais Armangue, Gisela Sugranyes, Heike Stein, Laia Prades, Helena Ariño, Jesús Planagumà, Elena De La Serna, Domingo Escudero, Sara Llufriu, Raquel Sánchez-Valle, Joan Santamaria, Albert Compte, Josefina Castro-Fornieles, Josep Dalmau
Publikováno v:
Monday, April 24.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d6e585cbdcb57393df02e88b2abda1
https://doi.org/10.1212/wnl.0000000000202506
https://doi.org/10.1212/wnl.0000000000202506
Autor:
Estibaliz Maudes, Francesco Mannara, Anna García‐Serra, Marija Radosevic, Araceli Mellado, Ana Beatriz Serafim, Jesús Planagumà, Lidia Sabater, Josep Dalmau, Marianna Spatola
Publikováno v:
Annals of Neurology. 92:81-86
Ophelia syndrome or encephalitis with antibodies against the metabotropic glutamate receptor 5 (mGluR5) manifests with behavioral changes, memory deficits, and anxiety. To study the antibody pathogenicity, mice received continuous cerebroventricular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ed82094dd91ab53dac3c8b61814a76
https://doi.org/10.1002/ana.26362
https://doi.org/10.1002/ana.26362
Publikováno v:
Journal of Visualized Experiments.
Over the last 15 years, a new category of antibody-mediated diseases of the central nervous system (CNS) has been characterized and is now defined as "autoimmune encephalitis" (AE). There are currently 17 known AE syndromes, and all are associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6047d44484624cd417f0cad95c4922db
https://doi.org/10.3791/63829
https://doi.org/10.3791/63829
Autor:
Bastien Joubert, Mar Petit‐Pedrol, Jesús Planagumà, Francesco Mannara, Marija Radosevic, Maria Marsal, Estibaliz Maudes, Anna García‐Serra, Esther Aguilar, Alba Andrés‐Bilbé, Xavier Gasull, Pablo Loza‐Alvarez, Lidia Sabater, Myrna R. Rosenfeld, Josep Dalmau
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Universitat Politècnica de Catalunya (UPC)
The encephalitis associated with antibodies against contactin-associated proteinlike 2 (CASPR2) is presumably antibody-mediated, but the antibody effects and whether they cause behavioral alterations are not well known. Here, we used a mouse model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34988ebd789fd4d550ebc7cf30bd390c
https://hdl.handle.net/2117/363805
https://hdl.handle.net/2117/363805
Autor:
Josep Dalmau, Marc Carceles-Cordon, Esther Aguilar, Francesco Mannara, Jesús Planagumà, Aida Castellanos
Publikováno v:
Annals of Neurology. 88:603-613
OBJECTIVE The aim was to demonstrate that antibodies from patients with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis alter the levels of dopamine 1 receptor (D1R) and dopamine 2 receptor (D2R) and cause psychotic-like features in mice. MET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c975837da38a8c978de5582495f19f0
https://doi.org/10.1002/ana.25829
https://doi.org/10.1002/ana.25829
Autor:
Marija Radosevic, Jesús Planagumà, Francesco Mannara, Araceli Mellado, Esther Aguilar, Lidia Sabater, Jon Landa, Anna García-Serra, Estibaliz Maudes, Xavier Gasull, Mike Lewis, Josep Dalmau
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
Dipòsit Digital de la UB
Universidad de Barcelona
article-version (Version of Record) 3
Dipòsit Digital de la UB
Universidad de Barcelona
Background and ObjectivesTo demonstrate that an analog (SGE-301) of a brain-derived cholesterol metabolite, 24(S)-hydroxycholesterol, which is a selective positive allosteric modulator (PAM) of NMDA receptors (NMDARs), is able to reverse the memory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789bc9b5e3ea2039c2648c29878136ed
http://europepmc.org/articles/PMC8669659
http://europepmc.org/articles/PMC8669659
Autor:
Grace Jachimiec, Negin Jalali Motlagh, Chih-Chung Lin, Enrico Kuellenberg, Jesús Planagumà, Gregory Wojtkiewicz, John Chen, Jenny Linnoila
Publikováno v:
Neurology. 99:S59.1-S59
ObjectiveTo identify and develop the optimal active immunization induction method for NMDAR encephalitis in rodents.BackgroundEncephalitis is a devastating neurologic disorder with high morbidity and mortality. Many cases are autoimmune. N-Methyl-D-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::667560c497940b47b4517ff028f7e5df
https://doi.org/10.1212/01.wnl.0000903468.46642.e8
https://doi.org/10.1212/01.wnl.0000903468.46642.e8