Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Jesús Picó"'
Autor:
Alba González-Cebrián, Joan Borràs-Ferrís, Yadira Boada, Alejandro Vignoni, Alberto Ferrer, Jesús Picó
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
One of the most common sources of information in Synthetic Biology is the data coming from plate reader fluorescence measurements. These experiments provide a measure of the light emitted by a certain fluorescent molecule, such as the Green Fluoresce
Externí odkaz:
https://doaj.org/article/749a54cd0ce54b95b08658bbc34f734f
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Achieving optimal production in microbial cell factories, robustness against changing intracellular and environmental perturbations requires the dynamic feedback regulation of the pathway of interest. Here, we consider a merging metabolic pathway mot
Externí odkaz:
https://doaj.org/article/2ee89b64021e4b8db14a76a019ba4ac4
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101305- (2020)
Summary: Transcription factor-based biosensors naturally occur in metabolic pathways to maintain cell growth and to provide a robust response to environmental fluctuations. Extended metabolic biosensors, i.e., the cascading of a bio-conversion pathwa
Externí odkaz:
https://doaj.org/article/31f9224a6dcd4fcfb7e36c48ae9ebb13
Publikováno v:
Applied Sciences, Vol 11, Iss 13, p 5859 (2021)
Optimal gene expression is central for the development of both bacterial expression systems for heterologous protein production, and microbial cell factories for industrial metabolite production. Our goal is to fulfill industry-level overproduction d
Externí odkaz:
https://doaj.org/article/32acfa7597c0494187cd00f01d03e635
Publikováno v:
Revista Iberoamericana de Automática e Informática Industrial RIAI, Vol 12, Iss 3, Pp 241-252 (2015)
Resumen: Durante la ultima década hemos vivido una creciente aplicación de técnicas propias de las ingenierías a la biología. Áreas como la Biología de Sistemas o, más recientemente, la Biología Sintética, reciben una atención cada vez may
Externí odkaz:
https://doaj.org/article/2a1453d988f944ef8b0f7042b2330e24
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2385
Semi-mechanistic kinetic (i.e., dynamic) models based on first principles are particularly relevant in biology, as they can explain and predict functional behavior that arises from varying concentrations of the cellular components over time. Here, we
Publikováno v:
ACS Synthetic Biology
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
[EN] Models of gene expression considering host-circuit interactions are relevant for understanding both the strategies and associated trade-offs that cell endogenous genes have evolved and for the efficient design of heterologous protein expression
Publikováno v:
IFAC-PapersOnLine. 52:156-162
The design and implementation of biomolecular feedback control strategies embedded within large biomolecular synthetic systems is one of the key areas of Synthetic Biology. Many important challenges remain to be addressed. Among them, the lack of rea
Publikováno v:
IFAC-PapersOnLine. 52:1-6
Signal tracking and the related signal derivative estimation are key pieces in feedback control engineered systems. In this work we present a synthetic biomolecular circuit that performs signal tracking with high precision under mild conditions on it
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Advances in genetic manipulation have allowed the overexpression of proteins and insertion of circuits in cells. However, the expected behaviour can be altered by the internal competition for the limited amount of cellular resources. In this work we