Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

Autor: Odessica Hughes, Amy R. Bentley, Charles E. Breeze, Francois Aguet, Xiaoguang Xu, Girish Nadkarni, Quan Sun, Bridget M. Lin, Thomas Gilliland, Mariah C. Meyer, Jiawen Du, Laura M. Raffield, Holly Kramer, Robert W. Morton, Mateus H. Gouveia, Elizabeth G. Atkinson, Adan Valladares-Salgado, Niels Wacher-Rodarte, Nicole D. Dueker, Xiuqing Guo, Yang Hai, Adebowale Adeyemo, Lyle G. Best, Jianwen Cai, Guanjie Chen, Michael Chong, Ayo Doumatey, James Eales, Mark O. Goodarzi, Eli Ipp, Marguerite Ryan Irvin, Minzhi Jiang, Alana C. Jones, Charles Kooperberg, Jose E. Krieger, Ethan M. Lange, Matthew B. Lanktree, James P. Lash, Paulo A. Lotufo, Ruth J.F. Loos, Vy Thi Ha My, Jesús Peralta-Romero, Lihong Qi, Leslie J. Raffel, Stephen S. Rich, Erik J. Rodriquez, Eduardo Tarazona-Santos, Kent D. Taylor, Jason G. Umans, Jia Wen, Bessie A. Young, Zhi Yu, Ying Zhang, Yii-Der Ida Chen, Tanja Rundek, Jerome I. Rotter, Miguel Cruz, Myriam Fornage, Maria Fernanda Lima-Costa, Alexandre C. Pereira, Guillaume Paré, Pradeep Natarajan, Shelley A. Cole, April P. Carson, Leslie A. Lange, Yun Li, Eliseo J. Perez-Stable, Ron Do, Fadi J. Charchar, Maciej Tomaszewski, Josyf C. Mychaleckyj, Charles Rotimi, Andrew P. Morris, Nora Franceschini

Publikováno v: Cell Genomics, Vol 4, Iss 1, Pp 100468- (2024)

Summary: Chronic kidney disease is a leading cause of death and disability globally and impacts individuals of African ancestry (AFR) or with ancestry in the Americas (AMS) who are under-represented in genome-wide association studies (GWASs) of kidne

Externí odkaz: https://doaj.org/article/975974e930614de28f7b1b95b70b9859

Low abundance of Akkermansia muciniphila and low consumption of polyphenols associated with metabolic disorders in child population

Autor: Margarita Bahena-Román, Ilse A. Gutiérrez-Pérez, Yaneth Citlalli Orbe-Orihuela, Cinthya E. Díaz-Benítez, Alfredo Lagunas-Martínez, Juan Carlos Ayala-García, Ana Cristina Castañeda-Márquez, Víctor Hugo Bermúdez-Morales, Jesús Peralta-Romero, Miguel Cruz, Ana I. Burguete-García

Publikováno v: Human Nutrition & Metabolism, Vol 30, Iss , Pp 200167- (2022)

A polyphenol-rich diet modulates the abundance of Akkermansia muciniphila (A. muciniphila), protecting against metabolic disorders caused by several pathologies such as obesity. The aim of this study was to determine if the polyphenol intake and the

Externí odkaz: https://doaj.org/article/f09939f445504359972e11251e999b53

Association of β1 and β3 adrenergic receptors gene polymorphisms with insulin resistance and high lipid profiles related to type 2 diabetes and metabolic syndrome

Autor: Ana I. Burguete-García, Gabriela A. Martínez-Nava, Adán Valladares-Salgado, V. H. Bermúdez, Bárbara Estrada-Velasco, Niels Wacher, Jesús Peralta-Romero, Jaime Garcia-Mena, Esteban Parra, Miguel Cruz

Publikováno v: Nutrición Hospitalaria, Vol 29, Iss 6, Pp 1327-1334 (2014)

Background: Among the diverse genes associated to type 2 diabetes (T2D), the β-adrenergic receptors are an excellent candidate to study in Mexican population. The objective of this work was to analyze the association of polymorphisms in ADRB1 (rs180

Externí odkaz: https://doaj.org/article/3661d2366fed4b16aadd42d2ee00344d

Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits—The Hispanic/Latino Anthropometry Consortium

Autor: Fernández-Rhodes, Lindsay, Graff, Mariaelisa, Buchanan, Victoria L., Justice, Anne E., Highland, Heather M., Guo, Xiuqing, Zhu, Wanying, Chen, Hung-Hsin, Young, Kristin L., Adhikari, Kaustubh, Palmer, Nicholette D., Below, Jennifer E., Bradfield, Jonathan, Pereira, Alexandre C., Glover, LáShauntá, Kim, Daeeun, Lilly, Adam G., Shrestha, Poojan, Thomas, Alvin G., Zhang, Xinruo, Chen, Minhui, Chiang, Charleston W.K., Pulit, Sara, Horimoto, Andrea, Krieger, Jose E., Guindo-Martínez, Marta, Preuss, Michael, Schumann, Claudia, Smit, Roelof A.J., Torres-Mejía, Gabriela, Acuña-Alonzo, Victor, Bedoya, Gabriel, Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Gallo, Carla, González-José, Rolando, Poletti, Giovanni, Rothhammer, Francisco, Hakonarson, Hakon, Igo, Robert, Adler, Sharon G., Iyengar, Sudha K., Nicholas, Susanne B., Gogarten, Stephanie M., Isasi, Carmen R., Papnicolaou, George, Stilp, Adrienne M., Qi, Qibin, Kho, Minjung, Smith, Jennifer A., Langefeld, Carl D., Wagenknecht, Lynne, Mckean-Cowdin, Roberta, Gao, Xiaoyi Raymond, Nousome, Darryl, Conti, David V., Feng, Ye, Allison, Matthew A., Arzumanyan, Zorayr, Buchanan, Thomas A., Ida Chen, Yii-Der, Genter, Pauline M., Goodarzi, Mark O., Hai, Yang, Hsueh, Willa, Ipp, Eli, Kandeel, Fouad R., Lam, Kelvin, Li, Xiaohui, Nadler, Jerry L., Raffel, Leslie J., Roll, Kathryn, Sandow, Kevin, Tan, Jingyi, Taylor, Kent D., Xiang, Anny H., Yao, Jie, Audirac-Chalifour, Astride, de Jesus Peralta Romero, Jose, Hartwig, Fernando, Horta, Bernando, Blangero, John, Curran, Joanne E., Duggirala, Ravindranath, Lehman, Donna E., Puppala, Sobha, Fejerman, Laura, John, Esther M., Aguilar-Salinas, Carlos, Burtt, Noël P., Florez, Jose C., García-Ortíz, Humberto, González-Villalpando, Clicerio, Mercader, Josep, Orozco, Lorena, Tusié-Luna, Teresa, Blanco, Estela, Gahagan, Sheila, Cox, Nancy J., Hanis, Craig, Butte, Nancy F., Cole, Shelley A., Comuzzie, Anthony G., Voruganti, V. Saroja, Rohde, Rebecca, Wang, Yujie, Sofer, Tamar, Ziv, Elad, Grant, Struan F.A., Ruiz-Linares, Andres, Rotter, Jerome I., Haiman, Christopher A., Parra, Esteban J., Cruz, Miguel, Loos, Ruth J.F., North, Kari E.

Publikováno v: In Human Genetics and Genomics Advances 14 April 2022 3(2)

Asociación del polimorfismo rs5186 del gen AGTR1 con disminución de la TFGe en pacientes con diabetes tipo 2 de la Ciudad de México. (Spanish)

Autor: Contreras Figueroa, Manuel Alejandro, Mendoza Lujambio, Irene, Alvarado Gutiérrez, Teresa, Pérez Hernández, María Fernanda, Estrada Ramírez, Evelyn Yazmín, Jiménez Guzmán, Dominga, Lucas Sánchez, María Fernanda, González Morales, Hannia Fernanda, Gómez Zamudio, Héctor Jaime, Suarez Sánchez, Fernando, Díaz Flores, Margarita, Jiménez Zamarripa, Carlos Alberto, Calzada Mendoza, Claudia Camelia, Ocharán Hernández, María Esther, Orozco Velázquez, Cora Mariana, Soto Flores, Mariana, Hernández Orozco, Daniela Vicenta, Cortés Moreno, Gabriela Yanet, Cruz, Miguel, de Jesús Peralta Romero, José

Publikováno v: Nefrologia; Sep/Oct2023, Vol. 43 Issue 5, p546-561, 16p