EHTIC study: Evaluation of a new hemostatic agent based on tissue factor in skin grafting procedures

Autor: Juan Ramón Esteban Vico, Carlos Brage, Santiago Rojas, Abel Llinas, Jesús Murat, M. Dolores Pérez del Caz, Ramón López, José Ramón Martinez, Javier Valero, Eugenia López-Suso, Jose Luis Fernandez-Cañamaque, Alba González Rodríguez, Juan Garcia Barreiro, Eloísa Villaverde

Publikováno v: Burns. 43:780-788

Excessive bleeding is a major concern in scar debridement and grafting procedures. TT-173 is a new topical hemostatic agent based on recombinant human tissue factor that has shown promising results in patients who underwent tooth extraction. EHTIC st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9febaf899ac86dc0e41015ee5e71e91
https://doi.org/10.1016/j.burns.2017.01.007

Characterization of the Biodistribution and Systemic Absorption of TT-173, a New Hemostatic Agent of Recombinant Human Tissue Factor, Using Radiolabeling with 18F

Autor: Santiago Rojas, Juan Domingo Gispert, José Raúl Herance, Pilar Sánchez, Jesús Murat, Ignasi Miquel, Ramón López, Esther Rincón, Belén Arias

Publikováno v: European Journal of Drug Metabolism and Pharmacokinetics. 42:583-592

TT-173 is the first topical hemostatic agent based on tissue factor. To prevent thromboembolic events and intravascular coagulation it is necessary to rule out the systemic absorption of new bioactive hemostats. Here, we radiolabeled TT-173 with [18F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e6905cec8089500f8c268cff8e9faa
https://doi.org/10.1007/s13318-016-0366-x

A new topical hemostatic agent TT-173 reduces blood loss in a sheep model of total knee arthroplasty

Autor: Ramón López, Santiago Rojas, Ignasi Miquel, Jesús Murat, Alberto Centeno, Esther Rincón, Pilar Sánchez, Belén Arias, Claudia Ureta

Publikováno v: The Knee. 24(6)

Background Total knee arthroplasty is associated with blood loss during the intervention and may require allogenic blood transfusion. Treatments such as tranexamic acid and fibrin sealants improved the bleeding control in several clinical trials, but

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84418e182d56803588a06e4d2c5dbac3
https://pubmed.ncbi.nlm.nih.gov/28865948

Analytical parameters and vital signs in patients subjected to dental extraction

Autor: Santiago Rojas, José López-López, Enric Jané-Pallí, Beatriz González-Navarro, Jesús Murat, Carlos Arranz-Obispo, Raul Ayuso-Montero, Amparo Santamaría, Enric Jané-Salas

Publikováno v: Journal of Clinical and Experimental Dentistry
Jané Pallí, Enric ; Arranz-Obispo, Carlos ; González Navarro, Beatriz ; Murat, Jesús ; Ayuso Montero, Raúl ; Rojas, Santiago ; Santamaría, Amparo ; Jane Salas, Enric ; López López, José. Analytical parameters and vital signs in patients subjected to dental extraction. En: Journal of Clinical and Experimental Dentistry. 2017. Vol. 9, no. 2: 223
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
Recercat. Dipósit de la Recerca de Catalunya
Dipòsit Digital de la UB
Universidad de Barcelona

BACKGROUND: Dental consultation may provoke stress to the patient, especially when a dental surgery is going to be performed, stressful situations can cause a reaction in the sympathetic nervous system that could lead to cardiovascular alterations. B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eecfed73e985de4f6d586945d14a1e75
https://pubmed.ncbi.nlm.nih.gov/28210440

Experimental Evaluation of a New Tissue Factor-Based Topical Hemostat (TT-173) for Treatment of Hepatic Bleeding.

Autor: Centeno, Alberto¹ (AUTHOR), Rojas, Santiago^2,3 (AUTHOR) santiagorojas@thrombotargets.com, Arias, Belén² (AUTHOR), Miquel, Ignasi² (AUTHOR), Sánchez, Pilar² (AUTHOR), Ureta, Claudia² (AUTHOR), Rincón, Esther² (AUTHOR), López, Ramón² (AUTHOR), Murat, Jesús² (AUTHOR)

Publikováno v: Journal of Investigative Surgery. Apr2020, Vol. 33 Issue 4, p339-349. 11p.