Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Jesús M Paramio"'
Autor:
Sandra P. Nunes, Lucia Morales, Carolina Rubio, Ester Munera-Maravilla, Iris Lodewijk, Cristian Suárez-Cabrera, Victor G. Martínez, Mercedes Pérez-Escavy, Miriam Pérez-Crespo, Miguel Alonso Sánchez, Esther Montesinos, Edurne San José-Enériz, Xabier Agirre, Felipe Prósper, Antonio Pineda-Lucena, Rui Henrique, Marta Dueñas, Margareta P. Correia, Carmen Jerónimo, Jesús M. Paramio
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Alterations in the epigenetic machinery in both tumor and immune cells contribute to bladder cancer (BC) development, constituting a promising target as an alternative therapeutic option. Here, we have explored the effects of a novel histone
Externí odkaz:
https://doaj.org/article/2e7cebeed11f4705be37c46da8ae9498
Autor:
Mauricio Menacho-Márquez, Ramón García-Escudero, Virginia Ojeda, Antonio Abad, Pilar Delgado, Clotilde Costa, Sergio Ruiz, Balbino Alarcón, Jesús M Paramio, Xosé R Bustelo
Publikováno v:
PLoS Biology, Vol 11, Iss 7, p e1001615 (2013)
The catalytic activity of GDP/GTP exchange factors (GEFs) is considered critical to maintain the typically high activity of Rho GTPases found in cancer cells. However, the large number of them has made it difficult to pinpoint those playing proactive
Externí odkaz:
https://doaj.org/article/e74b0d4836c441568451f8d3957139dd
Autor:
Marta Dueñas, Mirentxu Santos, Juan F Aranda, Concha Bielza, Ana B Martínez-Cruz, Corina Lorz, Miquel Taron, Eva M Ciruelos, José L Rodríguez-Peralto, Miguel Martín, Pedro Larrañaga, Jubrail Dahabreh, George P Stathopoulos, Rafael Rosell, Jesús M Paramio, Ramón García-Escudero
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42494 (2012)
Mutations in the TP53 gene are very common in human cancers, and are associated with poor clinical outcome. Transgenic mouse models lacking the Trp53 gene or that express mutant Trp53 transgenes produce tumours with malignant features in many organs.
Externí odkaz:
https://doaj.org/article/aa4b88e29f75412e9bf812a4c6c27a2d
Autor:
Águeda Buitrago-Pérez, Mariam Hachimi, Marta Dueñas, Belén Lloveras, Almudena Santos, Almudena Holguín, Blanca Duarte, Juan Luis Santiago, Baki Akgül, José L Rodríguez-Peralto, Alan Storey, Catalina Ribas, Fernando Larcher, Marcela del Rio, Jesús M Paramio, Ramón García-Escudero
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41743 (2012)
Human papillomavirus (HPV) is the causative agent of human cervical cancer and has been associated with oropharyngeal squamous cell carcinoma development. Although prophylactic vaccines have been developed, there is a need to develop new targeted the
Externí odkaz:
https://doaj.org/article/fed144444915485a951d8fe3bfd17c3f
Autor:
Mónica Fernández‐Cortés, Daniel Delgado‐Bellido, Eloísa Bermúdez‐Jiménez, Jesús M Paramio, Francisco O'Valle, Stefan Vinckier, Peter Carmeliet, Angel Garcia‐Diaz, F Javier Oliver
Publikováno v:
Fernández-Cortés, M, Delgado-Bellido, D, Bermúdez-Jiménez, E, Paramio, J M, O'Valle, F, Vinckier, S, Carmeliet, P, Garcia-Diaz, A & Oliver, F J 2023, ' PARP inhibition promotes endothelial-like traits in melanoma cells and modulates pericyte coverage dynamics during vasculogenic mimicry ', Journal of Pathology, vol. 259, no. 3, pp. 318-330 . https://doi.org/10.1002/path.6043
Vasculogenic mimicry (VM) describes the ability of highly aggressive tumor cells to develop pseudovascular structures without the participation of endothelial cells. PARP1 is implicated in the activation of hypoxia-inducible factors, which are crucia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044de670cce5af61d066b4dbb34cd688
https://doi.org/10.1002/path.6043
https://doi.org/10.1002/path.6043
Autor:
Jesús M Paramio
Publikováno v:
Immuno Oncology Insights. :417-422
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffe183599602a09180000d128a36071f
https://doi.org/10.18609/ioi.2022.045
https://doi.org/10.18609/ioi.2022.045
Autor:
Cristian Suarez-Cabrera, Lidia Estudillo, Erik Ramón-Gil, Mónica Martínez-Fernández, Jorge Peral, Carolina Rubio, Iris Lodewijk, Álvaro Martín de Bernardo, Ramón García-Escudero, Felipe Villacampa, José Duarte, Federico de la Rosa, Daniel Castellano, Félix Guerrero-Ramos, Francisco X. Real, Núria Malats, Jesús M. Paramio, Marta Dueñas
Publikováno v:
European Urology. 82:663-667
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661a2da42e526d2de750a95f66ff6ca0
https://doi.org/10.1016/j.eururo.2022.08.011
https://doi.org/10.1016/j.eururo.2022.08.011
Autor:
Angel Ramirez, Manuel Navarro, Jesús M. Paramio, José C. Segovia, Carmen Segrelles, Corina Lorz, M. Llanos Casanova, Josefa P. Alameda, Cristian Suarez-Cabrera, Ana Bravo, Angustias Page
CD34+ cell chaacterization in K5-IKKbeta skin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72911ab6e7c0b9b6834b877cf37f68d
https://doi.org/10.1158/1541-7786.22516390
https://doi.org/10.1158/1541-7786.22516390
Autor:
Angel Ramirez, Manuel Navarro, Jesús M. Paramio, José C. Segovia, Carmen Segrelles, Corina Lorz, M. Llanos Casanova, Josefa P. Alameda, Cristian Suarez-Cabrera, Ana Bravo, Angustias Page
Primer sequences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d13169ed27e243d47e898190419de8
https://doi.org/10.1158/1541-7786.22516375.v1
https://doi.org/10.1158/1541-7786.22516375.v1
Autor:
Angel Ramirez, Manuel Navarro, Jesús M. Paramio, José C. Segovia, Carmen Segrelles, Corina Lorz, M. Llanos Casanova, Josefa P. Alameda, Cristian Suarez-Cabrera, Ana Bravo, Angustias Page
Legends to Supplementary Figures and supplementary Material and Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624214da3e9961ce77222abaf7a6dcba
https://doi.org/10.1158/1541-7786.22516378
https://doi.org/10.1158/1541-7786.22516378