Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jesús Hernandez-Monge"'
Autor:
Mayra Martínez-Sánchez, Mariana Moctezuma-Dávila, Jesús Hernandez-Monge, Martha Rangel-Charqueño, Vanesa Olivares-Illana
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234337 (2020)
Loss of retinoblastoma (RB) function in the cone cells during retina development is necessary but not sufficient for retinoblastoma development. It has been reported that in the absence of RB activity, a retinoma is generated, and the onset of retina
Externí odkaz:
https://doaj.org/article/ce75bce0a1944f64a26c163fcbb212b3
Publikováno v:
The FEBS Journal. 289:4371-4382
The retinoblastoma gene (RB1) was the first tumour suppressor cloned; the role of its protein product (RB) as the principal driver of the G1 checkpoint in cell cycle control has been extensively studied. However, many other RB functions are continuou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1426e8fe386b5079a5fab998d1a45b38
https://doi.org/10.1111/febs.16035
https://doi.org/10.1111/febs.16035
Autor:
Jesús Hernandez-Monge, Vanesa Olivares-Illana, Adriana Rousset-Roman, Ixaura Medina-Medina, Mayra Martínez-Sánchez
Publikováno v:
EMBO Rep
The retinoblastoma tumour suppressor protein (RB) regulates a number of diverse cellular functions including differentiation, angiogenesis, chromatin remodelling, senescence and apoptosis. The best-characterised function of RB is cell cycle regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c390916f8e961488d2ea91204efe33
https://europepmc.org/articles/PMC7788445/
https://europepmc.org/articles/PMC7788445/
Autor:
Vanesa Olivares-Illana, Robin Fåhraeus, Jesús Hernandez-Monge, Ixaura Medina-Medina, Petr Müller, Mayra Martínez-Sánchez
Publikováno v:
Protein Science. 27:976-986
HDM2 and HDMX are two homologs essential for controlling p53 tumor suppressor activity under normal conditions. Both proteins bind different sites on the p53 N-terminus, and while HDM2 has E3 ubiquitin ligase activity towards p53, HDMX does not. Neve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e40ba9a91d797ad5324b749b018d94
https://doi.org/10.1002/pro.3405
https://doi.org/10.1002/pro.3405
Autor:
Mariana Moctezuma-Dávila, Mayra Martínez-Sánchez, Jesús Hernandez-Monge, Martha Rangel-Charqueño, Vanesa Olivares-Illana
Retinoblastoma is a pediatric neoplasia with a high incidence in non-developed countries. Nowadays the diagnosis is clinical and unfortunately in advanced stages of the diseases, which puts the child’s life risk. The search for molecular diagnosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194493e59b239e62b47270bb5dee1adb
Publikováno v:
Genes & Cancer
The orchestrated crosstalk between the retinoblastoma (RB) and p53 pathways contributes to preserving proper homeostasis within the cell. The deregulation of one or both pathways is a common factor in the development of most types of human cancer. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8b592ef40dadc0ded75924478afb43
http://europepmc.org/articles/PMC5115168
http://europepmc.org/articles/PMC5115168
Autor:
María Esther Herrera-Aguirre, Juan Pedro Luna-Arias, Jesús Hernandez-Monge, Karla Grisel Calderón-González
Publikováno v:
Modern Proteomics – Sample Preparation, Analysis and Practical Applications ISBN: 9783319414461
Biological systems function via intricate cellular processes and networks in which RNAs, metabolites, proteins and other cellular compounds have a precise role and are exquisitely regulated (Kumar and Mann, FEBS Lett 583(11):1703-1712, 2009). The dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6326640fccb06abb9bc6037826c4ec9b
https://doi.org/10.1007/978-3-319-41448-5_16
https://doi.org/10.1007/978-3-319-41448-5_16
Autor:
Tzitzijanik Madrigal, Jesús Hernández-Monge, Luis A Herrera, Claudia Haydée González-De la Rosa, Guadalupe Domínguez-Gómez, Myrna Candelaria, Fernando Luna-Maldonado, Karla G Calderón González, José Díaz-Chávez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The p53 roles have been largely described; among them, cell proliferation and apoptosis control are some of the best studied and understood. Interestingly, the mutations on the six hotspot sites within the region that encodes the DNA-binding domain o
Externí odkaz:
https://doaj.org/article/55c3b91e1f01494593591305e1b80358