Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Jesús Gonzalo Asensio"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Human and animal tuberculosis is caused by the Mycobacterium tuberculosis Complex (MTBC), which has evolved a genomic decay of cobalamin (vitamin B12) biosynthetic genes. Accordingly, and in sharp contrast to environmental, opportunistic and
Externí odkaz:
https://doaj.org/article/4c7f286e3a644e99bce19ffacfec4b65
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT The Mycobacterium tuberculosis Zaragoza (MtZ) strain has produced the largest outbreak in Aragon Community, Spain, as it started in the 90s and continues today, contributing with more than 240 cases of tuberculosis, around 10% of the TB case
Externí odkaz:
https://doaj.org/article/a95cfc7543a04c24849f5b113575d564
Publikováno v:
BMC Microbiology, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Macrophages play an essential role in the process of recognition and containment of microbial infections. These immune cells are recruited to infectious sites to reach and phagocytose pathogens. Specifically, in this article, bacteria from t
Externí odkaz:
https://doaj.org/article/70ecc78508334f30be2443a05fffc59f
Autor:
Juan Calvet-Seral, Estefanía Crespo-Yuste, Vanessa Mathys, Hector Rodriguez-Villalobos, Pieter-Jan Ceyssens, Anandi Martin, Jesús Gonzalo-Asensio
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT A bedaquiline-resistant Mycobacterium abscessus isolate was sequenced, and a candidate mutation in the atpE gene was identified as responsible for the antibiotic resistance phenotype. To establish a direct genotype-phenotype relationship of
Externí odkaz:
https://doaj.org/article/6e7ca9fac41e431e8570e5a28c44a941
Autor:
Irene Pérez, Elena Campos-Pardos, Caridad Díaz, Santiago Uranga, Fadel Sayes, Francisca Vicente, Nacho Aguiló, Roland Brosch, Carlos Martín, Jesús Gonzalo-Asensio
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 1235-1248 (2022)
Cyclic (di)nucleotides act as universal second messengers endogenously produced by several pathogens. Specifically, the roles of c-di-AMP in Mycobacterium tuberculosis immunity and virulence have been largely explored, although its contribution to th
Externí odkaz:
https://doaj.org/article/816e8da91577439ba1f2ef6ffc3163c6
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 2, Pp 395-414 (2022)
Summary Some bacteria have coevolved to establish symbiotic or pathogenic relationships with plants, animals or humans. With human association, the bacteria can cause a variety of diseases. Thus, understanding bacterial phenotypes at the single‐cel
Externí odkaz:
https://doaj.org/article/abad6b1e79de48fbac9ac0d0dfd226cf
Autor:
Esther Broset, Juan Calvet Seral, Carmen Arnal, Santiago Uranga, Alex I. Kanno, Luciana C.C. Leite, Carlos Martín, Jesús Gonzalo-Asensio
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4273-4283 (2021)
Live vaccines are attractive vehicles for antigen delivery as a strategy to immunize against heterologous pathogens. The live vaccine MTBVAC is based on rational attenuation of Mycobacterium tuberculosis with the objective of improving BCG protection
Externí odkaz:
https://doaj.org/article/a0aa4c6c152b42498f9386a4963c14ed
Autor:
Jessica Comín, Jan Madacki, Isabel Rabanaque, María Zúñiga-Antón, Daniel Ibarz, Alberto Cebollada, Jesús Viñuelas, Luis Torres, Juan Sahagún, Christophe Klopp, Jesús Gonzalo-Asensio, Roland Brosch, María-José Iglesias, Sofía Samper
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Since 2004, a tuberculosis surveillance protocol has been carried out in Aragon, thereby managing to detect all tuberculosis outbreaks that take place in the community. The largest outbreak was caused by a strain named Mycobacterium tuberculosis Zara
Externí odkaz:
https://doaj.org/article/35918df456cf4a1292565844155c5e2e
Autor:
Elena Mata, Damien Farrell, Ruoyao Ma, Santiago Uranga, Ana Belen Gomez, Marta Monzon, Juan Badiola, Alberto Anel, Jesús Gonzalo-Asensio, Carlos Martin, Stephen V Gordon, Nacho Aguilo
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009061 (2020)
Species belonging to the Mycobacterium tuberculosis Complex (MTBC) show more than 99% genetic identity but exhibit distinct host preference and virulence. The molecular genetic changes that underly host specificity and infection phenotype within MTBC
Externí odkaz:
https://doaj.org/article/534f6085cb604acda0e806cc85f98f78
Autor:
Juan Calvet-Seral, Estefanía Crespo-Yuste, Vanessa Mathys, Hector Rodriguez-Villalobos, Pieter-Jan Ceyssens, Anandi Martin, Jesús Gonzalo-Asensio
A bedaquiline resistantMycobacterium abscessusisolate was sequenced and a candidate mutation in theatpEgene was identified as responsible for the antibiotic resistance phenotype. To establish a direct genotype-phenotype relationship of this D29A muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcccc1f2716e94f4c5fa3f396e78c4f9
https://doi.org/10.1101/2022.12.01.518803
https://doi.org/10.1101/2022.12.01.518803
