Zobrazeno 1 - 10
of 403
pro vyhledávání: '"Jesús García-Foncillas"'
Autor:
Laura del Puerto-Nevado, María J. Fernández-Aceñero, Arancha Cebrián, Yuliia Fatych, Luis I. Díez-Valladares, Elia Pérez-Aguirre, Sofía de la Serna, Alejandra García-Botella, Javier Martínez-Useros, Jesús García-Foncillas, Pedro A. Mateos-Gómez
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundDNA polymerase theta (POLQ) is a translesion synthesis polymerase essential for the repair of double strand breaks by the error-prone TMEJ (Theta Mediated End Joining) pathway. Although POLQ participates in maintaining genome stability, sev
Externí odkaz:
https://doaj.org/article/0b3c55f609be443fb31ae697dcffea83
Autor:
Shaomin Zou, Yizhi Huang, Ziqing Yang, Jieping Zhang, Manqi Meng, Yijing Zhang, Junyan Feng, Rui Sun, Weiyao Li, Wencong Wang, Jesús García‐Foncillas López, Lekun Fang
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Background NOP2/Sun domain 2 (NSUN2) is one of the important RNA methyltransferases catalyzing 5‐methylcytosine (m5C) formation and participates in many critical bioprocesses. However, the roles and underlying molecular mechanisms of NSUN2
Externí odkaz:
https://doaj.org/article/26e23d0b2dc04d99b082fbce6001a3e9
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The immune system of people living with HIV (PLWH) is persistently exposed to antigens leading to systemic inflammation despite combination antiretroviral treatment (cART). This inflammatory milieu promotes T-cell activation and exhaustion. Furthermo
Externí odkaz:
https://doaj.org/article/a7b307119186420eac3802d288dc0ce9
Autor:
Juan Manuel Corral, Laura del Puerto-Nevado, Mabel Cedeño, Anxo Río-Vilariño, Ignacio Mahillo-Fernández, Carlos Galeano, Natalia Baños, Jesús García-Foncillas, Manuel Dómine, Arancha Cebrián
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113987- (2022)
Introduction: small-cell lung cancer (SCLC) is one of the most lethal malignancies. Its management is complex due to the lack of biomarkers and limited therapies. Galectin-1 (Gal-1) plays a major role in cancer development and progression. The aim of
Externí odkaz:
https://doaj.org/article/3881d83dc0a745b8889a15884f4ca2fc
Autor:
Cristina Martínez Leocadio, José García Villayzán, Jesús García‐Foncillas López, Franklin Idrovo, Javier Plaza Arranz, Manuel Albi González
Publikováno v:
Clinical Case Reports, Vol 7, Iss 12, Pp 2300-2305 (2019)
Abstract Gestational trophoblastic disease can result in serious complications and disease progression. Therefore, follow‐up of such patients is essential for early detection of malignant trophoblastic tumors and to reduce mortality rate. Primary t
Externí odkaz:
https://doaj.org/article/1715f80fde3a48b38cd89e667e59b425
Autor:
Sonia Solanes-Casado, Arancha Cebrián, María Rodríguez-Remírez, Ignacio Mahíllo, Laura García-García, Anxo Río-Vilariño, Natalia Baños, Guillermo de Cárcer, Ana Monfort-Vengut, Víctor Castellano, Maria Jesús Fernández-Aceñero, Jesús García-Foncillas, Laura del Puerto-Nevado
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112347- (2021)
New therapeutic targets are revolutionizing colorectal cancer clinical management, opening new horizons in metastatic patients’ outcome. Polo Like Kinase1 (PLK1) inhibitors have high potential as antitumoral agents, however, the emergence of drug r
Externí odkaz:
https://doaj.org/article/7e7044e51a4443f1bd9c0e6e88deaf7a
Publikováno v:
Psicosomática y Psiquiatría, Iss O (2021)
The risk of suicide in oncology is almost two times higher than in the general population, mainly associated to mental health disorders and diagnosis. A literature search of MEDLINE, PsycINFO, ISOC and CISNE between 2004-2015, yielded 823 articles of
Externí odkaz:
https://doaj.org/article/6f03d41d4091478680d206827efdfd09
Autor:
Iván Prieto-Potin, Franklin Idrovo, Ana Suárez-Gauthier, María Díaz-Blázquez, Laura Astilleros-Blanco de Córdova, Cristina Chamizo, Sandra Zazo, Nerea Carvajal, Almudena López-Sánchez, Sandra Pérez-Buira, Carmen Laura Aúz-Alexandre, Rebeca Manso, Jenifer Plaza-Sánchez, Virginia de Lucas-López, Nuria Pérez-González, Sara Martín-Valle, Ion Cristóbal, Victoria Casado, Jesús García-Foncillas, Federico Rojo
Publikováno v:
Diagnostics, Vol 12, Iss 8, p 1903 (2022)
Gynecological cancer accounts for an elevated incidence worldwide requiring responsiveness regarding its care. The comprehensive genomic approach agrees with the classification of certain tumor types. We evaluated 49 patients with gynecological tumor
Externí odkaz:
https://doaj.org/article/5997035934bb459c94fd59bc4cba53f2
Autor:
Enrique Aranda, Barbara Manzanares-Martin, Arancha Cebrián Aranda, Laura del Puerto-Nevado, Rafael González, Sonia Solanes, Maria Auxiliadora Gómez-España, Jesús García-Foncillas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Aim Cetuximab is a standard-of-care treatment for KRAS wild-type metastatic colorectal cancer (mCRC), but it may also be effective in a subgroup of KRAS mutant patients by its immunomodulatory activity. Here, we explore if KIR (killer cell immunoglob
Externí odkaz:
https://doaj.org/article/1734a5cc131b4a0fb898b7c944efcb18
Autor:
Jesús García-Foncillas MD, PhD, Antonio Antón-Torres MD, Fernando Caballero-Martínez MD, PhD, Francisco J Campos BS, Margarita Feyjoo MD, Alfonso Gómez de Liaño MD, Diana Monge MD, MPH, PhD, Carlos Camps MD, PhD
Publikováno v:
Journal of Patient Experience, Vol 7 (2020)
Pain in cancer is often underdiagnosed and undertreated. Breakthrough pain, in particular, severely impacts the quality of life of patients. In this study, we evaluated management and care of pain in Spain from the patient perspective by assessing th
Externí odkaz:
https://doaj.org/article/7d5d4acc9b4a4f3e9cf22bbd9f2620e8