Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Jesús Fernández-Felipe"'
1
Akademický článek
IL6/sIL6R regulates TNFα-inflammatory response in synovial fibroblasts through modulation of transcriptional and post-transcriptional mechanisms
Autor: Alvaro Valin, Manuel J. Del Rey, Cristina Municio, Alicia Usategui, Marina Romero, Jesús Fernández-Felipe, Juan D. Cañete, Francisco J. Blanco, Yolanda Ruano, Gabriel Criado, José L. Pablos
Publikováno v: BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Introduction The clinical efficacy of specific interleukin-6 inhibitors has confirmed the central role of IL6 in rheumatoid arthritis (RA). However the local role of IL6, in particular in synovial fibroblasts (SF) as a direct cellular target
Externí odkaz: https://doaj.org/article/d966f2637fe742f6aedba0c75a9ebd6b
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2
Akademický článek
Effect of Lauric vs. Oleic Acid-Enriched Diets on Leptin Autoparacrine Signalling in Male Mice
Autor: Jesús Fernández-Felipe, Adrián Plaza, Gema Domínguez, Javier Pérez-Castells, Victoria Cano, Francesco Cioni, Nuria Del Olmo, Mariano Ruiz-Gayo, Beatriz Merino
Publikováno v: Biomedicines, Vol 10, Iss 8, p 1864 (2022)
High-fat diets enriched with lauric acid (SOLF) do not enhance leptin production despite expanding white adipose tissue (WAT). Our study aimed at identifying the influence of SOLF vs. oleic acid-enriched diets (UOLF) on the autoparacrine effect of le
Externí odkaz: https://doaj.org/article/54b4bf57096d4b09b65a28db3643cf37
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3
Akademický článek
Differential Deleterious Impact of Highly Saturated Versus Monounsaturated Fat Intake on Vascular Function, Structure, and Mechanics in Mice
Autor: Elena Vega-Martín, Marta Gil-Ortega, Raquel González-Blázquez, Sara Benedito, Jesús Fernández-Felipe, Mariano Ruiz-Gayo, Nuria del Olmo, Julie A. Chowen, Laura M. Frago, Beatriz Somoza, María S. Fernández-Alfonso
Publikováno v: Nutrients, Vol 13, Iss 3, p 1003 (2021)
Vegetable oils such as palm oil (enriched in saturated fatty acids, SFA) and high-oleic-acid sunflower oil (HOSO, containing mainly monounsaturated fatty acids, MUFA) have emerged as the most common replacements for trans-fats in the food industry. T
Externí odkaz: https://doaj.org/article/7d07827153ee48ad83f4fce9c6e86bed
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5
Effects of saturated versus unsaturated fatty acids on metabolism, gliosis, and hypothalamic leptin sensitivity in male mice
Autor: Jesús Fernández-Felipe, Maria Valencia-Avezuela, Beatriz Merino, Beatriz Somoza, Victoria Cano, Ana B. Sanz-Martos, Laura M. Frago, Maria S. Fernández-Alfonso, Mariano Ruiz-Gayo, Julie A. Chowen
Publikováno v: Nutritional Neuroscience. 26:173-186
Development of obesity and its comorbidities is not only the result of excess energy intake, but also of dietary composition. Understanding how hypothalamic metabolic circuits interpret nutritional signals is fundamental to advance towards effective
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339ef1002f1f5a6826311f7b0da83604
https://doi.org/10.1080/1028415x.2022.2029294
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6
Regional specific effect of saturated vs unsaturated fat on leptin receptor signalling in mice brain areas regulating feeding
Autor: Jesús Fernández-Felipe, Lucía L. López, Victoria Cano, Enrique Sánchez-Hita, A. Belén Sanz, Julie A. Chowen, Nuria Del Olmo, Mariano Ruiz-Gayo, Beatriz Merino
Publikováno v: Neuroscience letters. 793
Leptin receptors (LepR) are expressed in brain areas controlling food intake homeostasis, such as the hypothalamus, the hippocampus and the prefrontal cortex. In a previous study we reported that long-term intake of saturated and monounsaturated fat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce1576ad2266165faa56cf37935dfbb
https://pubmed.ncbi.nlm.nih.gov/36481371
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7
Saturated and unsaturated triglyceride-enriched diets modify amino acid content in the mice hippocampus
Autor: Jesús Fernández-Felipe, Ana B. Sanz-Martos, Alberto Marcos, María P. Lorenzo, Victoria Cano, Beatriz Merino, Emilio Ambrosio, Nuria Del Olmo, Mariano Ruiz-Gayo
Publikováno v: Neuroscience Letters. 793:136972
Elevated intake of fat modulates l-glutamate (l-Glu) turnover within the hippocampus (HIP). Our aim has been to investigate the effect of saturated vs unsaturated fat on the content of l-Glu and other amino acids involved in synaptic transmission wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a878b17e348ddc04b06768e081912a
https://doi.org/10.1016/j.neulet.2022.136972
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8
Butyric Acid Precursor Tributyrin Modulates Hippocampal Synaptic Plasticity and Prevents Spatial Memory Deficits: Role of PPARγ and AMPK
Autor: Ana Belén Sanz-Martos, Jesús Fernández-Felipe, Beatriz Merino, Victoria Cano, Mariano Ruiz-Gayo, Nuria Del Olmo
Publikováno v: The international journal of neuropsychopharmacology. 25(6)
Background Short chain fatty acids (SCFA), such as butyric acid (BA), derived from the intestinal fermentation of dietary fiber and contained in dairy products, are gaining interest in relation to their possible beneficial effects on neuropsychologic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe27ce3ad3eac47033abc3f846ceee8f
https://pubmed.ncbi.nlm.nih.gov/35152284
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9
Differential Deleterious Impact of Highly Saturated Versus Monounsaturated Fat Intake on Vascular Function, Structure, and Mechanics in Mice
Autor: Mariano Ruiz-Gayo, Sara Benedito, María S. Fernández-Alfonso, Nuria Del Olmo, Raquel González-Blázquez, Laura M. Frago, Beatriz Somoza, Marta Gil-Ortega, Elena Vega-Martín, Jesús Fernández-Felipe, Julie A. Chowen
Publikováno v: Nutrients
Volume 13
Issue 3
Nutrients, Vol 13, Iss 1003, p 1003 (2021)
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
E-Prints Complutense. Archivo Institucional de la UCM
Vegetable oils such as palm oil (enriched in saturated fatty acids, SFA) and high‐oleic‐acid sunflower oil (HOSO, containing mainly monounsaturated fatty acids, MUFA) have emerged as the most common replacements for trans‐fats in the food indus
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae81dda6665a25f2cf4289104975486b
https://pubmed.ncbi.nlm.nih.gov/33808927
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10
Il6/Sil6R Regulates Tnfα-Inflammatory Response In Synovial Fibroblasts Through Modulation of Transcriptional and Post-Transcriptional Mechanisms
Autor: Marina Romero, Yolanda Ruano, José L. Pablos, Francisco J. Blanco, Alicia Usategui, Cristina Municio, Alvaro Valin, Gabriel Criado, Jesús Fernández-Felipe, Juan D. Cañete, Manuel J. Del Rey
Publikováno v: BMC Molecular and Cell Biology
RUC. Repositorio da Universidade da Coruña
instname
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-12 (2020)
RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
Introduction The clinical efficacy of specific interleukin-6 inhibitors has confirmed the central role of IL6 in rheumatoid arthritis (RA). However the local role of IL6, in particular in synovial fibroblasts (SF) as a direct cellular target to IL6/s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ff462129737279ed2447ac4a13bdce
https://doi.org/10.21203/rs.3.rs-32228/v1
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