Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Jesús Espinal-Enríquez"'
Autor:
Karen Griselda De la Cruz-López, Eduardo Alvarado-Ortiz, Heriberto A. Valencia-González, Fredy Omar Beltrán-Anaya, José María Zamora-Fuentes, Alfredo Hidalgo-Miranda, Elizabeth Ortiz-Sánchez, Jesús Espinal-Enríquez, Alejandro García-Carrancá
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Metformin, a widely prescribed antidiabetic drug, has shown several promising effects for cancer treatment. These effects have been shown to be mediated by dual modulation of the AMPK-mTORC1 axis, where AMPK acts upstream of mTORC
Externí odkaz:
https://doaj.org/article/f661298270d248fa9adb68a74b521d03
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
Aging is a universal and progressive process involving the deterioration of physiological functions and the accumulation of cellular damage. Gene regulation programs influence how phenotypes respond to environmental and intrinsic changes during aging
Externí odkaz:
https://doaj.org/article/1dfb1c85079d4d25acbfd865d4d29a02
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Hematopoietic cancers (HCs) are a heterogeneous group of malignancies that affect blood, bone marrow and lymphatic system. Here, by analyzing 1960 RNA-Seq samples from three independent datasets, we explored the co-expression landscape in HC
Externí odkaz:
https://doaj.org/article/9d2c5e89e56f42e181398df865fa2c37
Autor:
Mauricio M. González-Ballesteros, Luis Sánchez-Sánchez, Adrián Espinoza-Guillén, Jesús Espinal-Enríquez, Carmen Mejía, Enrique Hernández-Lemus, Lena Ruiz-Azuara
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8803 (2024)
Triple-negative breast cancer (TNBC), accounting for 15–20% of all breast cancers, has one of the poorest prognoses and survival rates. Metastasis, a critical process in cancer progression, causes most cancer-related deaths, underscoring the need f
Externí odkaz:
https://doaj.org/article/92d1f2a68cc54771bd61929db6592bdf
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Renal carcinomas are a group of malignant tumors often originating in the cells lining the small tubes in the kidney responsible for filtering waste from the blood and urine production. Kidney tumors arise from the uncontrolled growth of cells in the
Externí odkaz:
https://doaj.org/article/d2c93d5a284e41b79ce6ee9578f3c7a8
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17564 (2023)
Breast cancer encompasses a diverse array of subtypes, each exhibiting distinct clinical characteristics and treatment responses. Unraveling the underlying regulatory mechanisms that govern gene expression patterns in these subtypes is essential for
Externí odkaz:
https://doaj.org/article/30838aaffdbf4aa99f7bc4c29644ea00
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Gene co-expression networks are a useful tool in the study of interactions that have allowed the visualization and quantification of diverse phenomena, including the loss of co-expression over long distances in cancerous samples. This characteristic,
Externí odkaz:
https://doaj.org/article/c59eb01fd300422d938fe6cbc82840e3
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/166ca7a6c74d493085aadec91e30d50b
Autor:
Rodrigo Dorantes-Gilardi, Diana García-Cortés, Enrique Hernández-Lemus, Jesús Espinal-Enríquez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Gene co-expression networks (GCNs) have been developed as relevant analytical tools for the study of the gene expression patterns behind complex phenotypes. Determining the association between structure and function in GCNs is a current chal
Externí odkaz:
https://doaj.org/article/8a77833741c94473b5b282636b778343
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Clear cell renal carcinoma (ccRC) comprises a set of heterogeneous, fast-progressing pathologies with poor prognosis. Analyzing ccRC progression in terms of modifications at the molecular level may provide us with a broader understanding of the disea
Externí odkaz:
https://doaj.org/article/f854fa2bcdb24190b417bb92a323bae3