Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Jesús Bujía"'
Publikováno v:
American Journal of Rhinology. 12:59-64
In reconstructive surgery there is increasing demand for cartilage transplants to fill defects, especially nose and/or outer ear defects. Tissue engineering is one of the most modern pathways to generate autologous cartilage transplants. Isolated cho
Publikováno v:
Laryngo-Rhino-Otologie. 76:248-251
BACKGROUND We have developed a three-dimensional model for tissue engineering of cartilage. Chondrocytes were isolated and first multiplied in conventional monolayer cultures. Then the cells are seeded with or without agarose on special absorbable sc
Publikováno v:
Laryngo-Rhino-Otologie. 76:241-247
BACKGROUND: Recently a three-dimensional model for the formation of cartilage in vitro was developed. The aim of this study was to investigate the amount and quality of newly synthesized matrix after graftig in vitro engineered cartilage into athymic
Autor:
Gerd-Rüdiger Burmester, J. Bräunling, Michael Sittinger, Ernst Kastenbauer, Jesús Bujía, Claus Hammer
Publikováno v:
Laryngo-Rhino-Otologie. 76:96-100
BACKGROUND Recent developments in the field of tissue engineering provide novel approaches in tissue repair and reconstructive surgery using the patients own cells. Isolated chondrocytes form new cartilage when seeded in appropriate scaffolds. Usuall
Publikováno v:
The Laryngoscope. 106:217-220
Regardless of its origin, cholesteatoma is characterized by the presence of a keratinizing epithelium with an hyperproliferative behavior leading to a very important bone resorption. Previous studies have demonstrated overexpression of interleukin-1
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 253:152-157
Locally produced pro-inflammatory cytokines are considered to play an important role in the initiation and/or maintenance of inflammatory diseases. In cholesteatomatous lesions there are increased levels of some cytokines and inflammatory mediators l
Autor:
Jesús Bujía, Anja Holly, Holger Sudhoff, Ernst Kastenbauer, Mario Guzman Tapia, Francisco Antolí-Candela
Publikováno v:
ORL. 58:23-26
Cholesteatoma epithelium is characterized by a keratinocyte dysregulation with aggressive growth subsequently destroying the middle ear mucosa. The monoclonal antibody Ki-67 recognizes a nuclear antigen expressed by cells in the G1, S, and G2/M phase
Publikováno v:
Laryngo-Rhino-Otologie. 74:761-764
BACKGROUND Because of the limited availability of autologous tissue, stored allograft is commonly used. Before grafting, bank tissue is subjected to chemical preservation procedures. This procedure is important to diminish antigenicity and to inactiv
Publikováno v:
Laryngo-Rhino-Otologie. 74:450-455
A permanent change of shape of the auricle can be achieved by local application of papain to the elastic cartilage. To assess possible clinical use of papain, we investigated its effect on isolated and cultured chondrocytes derived from human cartila
Publikováno v:
Laryngo-Rhino-Otologie. 74:348-351
Cholesteatoma epithelium is characterised by a keratinocyte dysregulation with a hyperproliferative growth and altered differentiation. In a variety of cells c-myc oncogene was found to be highly linked to the control of growth and differentiation. T