Optimization of a Rabbit Dry Eye Model Induced by Topical Instillation of Benzalkonium Chloride

Autor: Carlos Carpena-Torres, Jesús Pintor, María Jesús Pérez de Lara, Fernando Huete-Toral, Almudena Crooke, Cristina Pastrana, Gonzalo Carracedo

Publikováno v: Journal of Ophthalmology, Vol 2020 (2020)

Purpose. To optimize a rabbit dry eye model induced by topical instillation of benzalkonium chloride (BAC), reduce the days of instillation of the original model by increasing the concentration of BAC from 0.1% to 0.2%. Materials and Methods. An expe

Externí odkaz: https://doaj.org/article/c7b88590b0ca4deaa6b3e0d35cffb373

Melatonin receptors in GtoPdb v.2023.1

Autor: Darius Paul Zlotos, Gianluca Tosini, David Sugden, Nicolas Renault, Jesús Pintor, James Olcese, Regina Pekelmann Markus, Diana N. Krause, Ralf Jockers, Margarita L. Dubocovich, Philippe Delagrange, Daniel P. Cardinali

Publikováno v: IUPHAR/BPS Guide to Pharmacology CITE. 2023

Melatonin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Melatonin Receptors [40]) are activated by the endogenous ligands melatonin and clinically used drugs like ramelteon, agomelatine and tasimelteon.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be1e7dd230a100bfa3e2fa456ace8290
https://doi.org/10.2218/gtopdb/f39/2023.1

The impact of polyphenols on chondrocyte growth and survival: a preliminary report

Autor: Salvador Fernández-Arroyo, Fernando Huete-Toral, María Jesús Pérez de Lara, María de la Luz Cádiz-Gurrea, Laurence Legeai-Mallet, Vicente Micol, Antonio Segura-Carretero, Jorge Joven, Jesús Pintor

Publikováno v: Food & Nutrition Research, Vol 59, Iss 0, Pp 1-10 (2015)

Background: Imbalances in the functional binding of fibroblast growth factors (FGFs) to their receptors (FGFRs) have consequences for cell proliferation and differentiation that in chondrocytes may lead to degraded cartilage. The toxic, proinflammato

Externí odkaz: https://doaj.org/article/dcda9fb0304f47188f9b22e395a13723

In vitro and in vivo delivery of the secretagogue diadenosine tetraphosphate from conventional and silicone hydrogel soft contact lenses

Autor: Carmen Olalla Dominguez-Godinez, Alba Martin-Gil, Gonzalo Carracedo, Ana Guzman-Aranguez, José Manuel González-Méijome, Jesús Pintor

Publikováno v: Journal of Optometry, Vol 6, Iss 4, Pp 205-211 (2013)

Purpose: To evaluate the possible use of soft contact lenses (CL) to improve the secretagogue role of diadenosine tetraphosphate (Ap4A) promoting tear secretion. Methods: Two conventional hydrogel CL (Omafilcon A and Ocufilcon D) and two silicone hyd

Externí odkaz: https://doaj.org/article/780cfcea4e1d42239a438be5e9f7470f

Efficacy of Artificial Tears Based on an Extract of Artemia salina Containing Dinucleotides in a Rabbit Dry Eye Model

Autor: Carlos Carpena-Torres, Alba Martin-Gil, Candela Rodríguez-Pomar, Fernando Huete-Toral, Alejandro Martínez-Águila, Jesús Pintor, Gonzalo Carracedo

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 11999, p 11999 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
E-Prints Complutense. Archivo Institucional de la UCM
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(1) Background: Artemia salina is a brine shrimp containing high concentrations of dinucleotides, molecules with properties for dry eye treatment. For this reason, the purpose of the study was to evaluate the effect of the artificial tears based on a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dbaa942f554a205ec21d562f4ba539
https://www.mdpi.com/1422-0067/22/21/11999