Genetic variants regulating the immune response improve the prediction of COVID-19 severity provided by clinical variables

Autor: Pablo Delgado-Wicke, Sara Fernández de Córdoba-Oñate, Emilia Roy-Vallejo, Estíbaliz Alegría-Carrasco, Diego A. Rodríguez-Serrano, Amalia Lamana, Nuria Montes, Ana Nicolao-Gómez, Rosa Carracedo-Rodríguez, Ana Marcos-Jiménez, Paula Díaz-Fernández, José M. Galván-Román, Laura Rabes-Rodríguez, Marta Sanz-Alba, Jesús Álvarez-Rodríguez, Almudena Villa-Martí, Carlos Rodríguez-Franco, Gonzalo Villapalos-García, Pablo Zubiaur, Francisco Abad-Santos, Ignacio de los Santos, Rosa P. Gomariz, Rosario García-Vicuña, Cecilia Muñoz-Calleja, Isidoro González-Álvaro, Elena Fernández-Ruiz, PREDINMUN-COVID Group

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Abstract The characteristics of the host are crucial in the final outcome of COVID-19. Herein, the influence of genetic and clinical variants in COVID-19 severity was investigated in a total of 1350 patients. Twenty-one single nucleotide polymorphism

Externí odkaz: https://doaj.org/article/0d1fc16c70a649cfaebb526fed6a8fbd

SARS-CoV-2 Viremia Precedes an IL6 Response in Severe COVID-19 Patients: Results of a Longitudinal Prospective Cohort

Autor: Emilia Roy-Vallejo, Laura Cardeñoso, Ana Triguero-Martínez, Marta Chicot Llano, Nelly Zurita, Elena Ávalos, Ana Barrios, Julia Hernando, Javier Ortiz, Sebastián C. Rodríguez-García, Marianela Ciudad Sañudo, Celeste Marcos, Elena García Castillo, Leticia Fontán García-Rodrigo, Begoña González, Rosa Méndez, Isabel Iturrate, Ancor Sanz-García, Almudena Villa, Ana Sánchez-Azofra, Begoña Quicios, David Arribas, Jesús Álvarez Rodríguez, Pablo Patiño, Marina Trigueros, Miren Uriarte, Alexandra Martín-Ramírez, Cristina Arévalo Román, José María Galván-Román, Rosario García-Vicuña, Julio Ancochea, Cecilia Muñoz-Calleja, Elena Fernández-Ruiz, Rafael de la Cámara, Carmen Suárez Fernández, Isidoro González-Álvaro, Diego A. Rodríguez-Serrano, the PREDINMUN-COVID Group, Jesús Sanz, Pedro Casado, Ángela Gutiérrez, Azucena Bautista, Pilar Hernández, Nuria Ruiz Giménez, Berta Moyano, Paloma Gil, María Jesús Delgado, Pedro Parra, Beatriz Sánchez, Carmen Sáez, Marta Fernández Rico, Diego Domingo García, Teresa Alarcón Cavero, María Auxiliadora Semiglia Chong, Ainhoa Gutiérrez Cobos, Santos Castañeda, Irene Llorente, Eva G. Tomero, Noelia García Castañeda, Nuria Montes, Cristina Dominguez Peña, David Jiménez Jiménez, Pablo Villamayor, Alfonso Canabal, Tamara Alonso, Carolina Cisneros, Claudia Valenzuela, Francisco Javier García Pérez, Rosa María Girón, Javier Aspa, M. del Perpetuo Socorro Churruca, Enrique Zamora, Adrián Martínez, Mar Barrio Mayo, Rosalina Henares Espi, Francisco Sánchez-Madrid, Enrique Martín Gayo, Ildefonso Sánchez-Cerrillo, Ana Marcos Jimenez, Pedro Martínez-Fleta, Celia López-Sanz, Ligia Gabrie, Luciana del Campo Guerola, Reyes Tejedor, Rosa Carracedo Rodríguez

Publikováno v: Frontiers in Medicine, Vol 9 (2022)

BackgroundInterleukin 6 (IL6) levels and SARS-CoV-2 viremia have been correlated with COVID-19 severity. The association over time between them has not been assessed in a prospective cohort. Our aim was to evaluate the relationship between SARS-CoV-2

Externí odkaz: https://doaj.org/article/2e8c5c8c3fe4433d9e6a941239aec30c

3D solid supported inter-polyelectrolyte complexes obtained by the alternate deposition of poly(diallyldimethylammonium chloride) and poly(sodium 4-styrenesulfonate)

Autor: Eduardo Guzmán, Armando Maestro, Sara Llamas, Jesús Álvarez-Rodríguez, Francisco Ortega, Ángel Maroto-Valiente, Ramón G. Rubio

Publikováno v: Beilstein Journal of Nanotechnology, Vol 7, Iss 1, Pp 197-208 (2016)

This work addresses the formation and the internal morphology of polyelectrolyte layers obtained by the layer-by-layer method. A multimodal characterization showed the absence of stratification of the films formed by the alternate deposition of poly(

Externí odkaz: https://doaj.org/article/6fefa49fedf342b8b9143b4b8da0955e

Stable anchoring of dispersed gold nanoparticles on hierarchic porous silica-based materialsElectronic supplementary information (ESI) available: Detailed information on the synthesis and characterisation of the CoOx-UVM-7 supports used is presented, including stability of the material under the working conditions. See DOI: 10.1039/c0jm00421a

Autor: Mónica Pérez-Cabero, Jamal El Haskouri, Benjamín Solsona, Isabel Vázquez, Ana Dejoz, Tomás García, Jesús Álvarez-Rodríguez, Aurelio Beltrán, Daniel Beltrán, Pedro Amorós

Publikováno v: Journal of Materials Chemistry; 8/28/2010, Vol. 20 Issue 32, p6780-6788, 9p