Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Jerzy W. Kolaczynski"'
1
Leptin-based therapeutics
Autor: Eva Surmacz, Laszlo Otvos, Laura Scolaro, Jerzy W. Kolaczynski, Marco Cassone
Publikováno v: Expert review of endocrinologymetabolism. 5(6)
Leptin, a pluripotent adipokine, has been discovered as a hormone controlling energy balance in hypothalamic neuroendocrine centers. In addition, recent studies provided ample evidence that leptin can be produced by cells other than adipocytes, and t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98ee767663e5fe164987b0eda440eb1
https://pubmed.ncbi.nlm.nih.gov/30780830
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2
Continuous Subcutaneous Insulin Infusion (CSII) of Insulin Aspart Versus Multiple Daily Injection of Insulin Aspart/Insulin Glargine in Type 1 Diabetic Patients Previously Treated With CSII
Autor: Wendy Lane, Peter Hu, Olga M. Santiago, Allen M Sussman, Jerzy W. Kolaczynski, Satish K. Garg, Bruce W. Bode, Irl B. Hirsch
Publikováno v: Diabetes Care. 28:533-538
OBJECTIVE—Multiple daily injection (MDI) therapy of bolus insulin aspart and basal insulin glargine was compared with continuous subcutaneous insulin infusion (CSII) with aspart in type 1 diabetic patients previously treated with CSII. RESEARCH DES
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6234987c62821f5ddacb7e7d7cf56b03
https://doi.org/10.2337/diacare.28.3.533
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3
Comparison of Insulin Aspart and Lispro
Autor: Carolyn C. Jimenez, Jerzy W. Kolaczynski, Carol J. Homko, Guenther Boden, Antonio Deluzio
Publikováno v: Diabetes Care. 26:2027-2031
OBJECTIVE—To compare insulin levels and actions in patients with type 1 diabetes after subcutaneous injection of the rapid-acting insulin analogs aspart and lispro. RESEARCH DESIGN AND METHODS—Seven C-peptide–negative patients with type 1 diabe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9974a75453bbcc7c35d94ab30bdf4141
https://doi.org/10.2337/diacare.26.7.2027
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4
Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects
Autor: Marcia Polansky, Xinhua Chen, Guenther Boden, Jerzy W. Kolaczynski
Publikováno v: Journal of Clinical Investigation. 100:1107-1113
We have studied the effect of prolonged hyperinsulinemia and hyperglycemia on serum leptin levels in young non- obese males during 72-h euglycemic-hyperinsulinemic and hyperglycemic ( z 8.5 and 12.6 mM) clamps. Hyperinsuline- mia increased serum lept
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee598628ec1a2bfdd848a3f64adea754
https://doi.org/10.1172/jci119621
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5
Dexamethasone stimulates leptin release from human adipocytes: Unexpected inhibition by insulin
Autor: John H. Moore, James W. Fox, Robert V. Considine, Jerzy W. Kolaczynski, Mark R. Nyce, Pei Li Zhang, Joanna P. Ohannesian, Jose F. Caro
Publikováno v: Journal of Cellular Biochemistry. 65:254-258
In the present study we have examined the effect of dexamethasone on ob gene mRNA expression and leptin release from isolated human subcutaneous adipocytes. Dexamethasone stimulated leptin release from cultured adipocytes in a time- and dose-dependen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a923bce416e0b39e3c4ab8e955f0fb6e
https://doi.org/10.1002/(sici)1097-4644(199705)65:2<254::aid-jcb10>3.0.co
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6
Mutation Screening and Identification of a Sequence Variation in the Human OB Gene Coding Region
Autor: Joanna P. Ohannesian, Robert V. Considine, Thomas L. Bauer, Irina Opentanova, Peili Zhang, E. Considine, John H. Moore, Jose F. Caro, Charlene J. Williams, Jerzy W. Kolaczynski, Mark R. Nyce
Publikováno v: Biochemical and Biophysical Research Communications. 220:735-739
In the present study mRNA from the subcutaneous adipose tissue of 68 obese (defined as a body mass indexor = 27.3 for men andor = 27.8 for women) and 38 lean subjects was screened for mutations in the ob gene coding region. No mutations in the coding
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9179f9143c82350259f0a6bb256268
https://doi.org/10.1006/bbrc.1996.0473
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8
Viability of fat obtained by syringe suction lipectomy: effects of local anesthesia with lidocaine
Autor: Jose F. Caro, John H. Moore, L. M. Morales, Jerzy W. Kolaczynski, Penny F. Noto, Zbigniew Pietrzkowski, Robert V. Considine
Publikováno v: Aesthetic Plastic Surgery. 19:335-339
The results of transplantation of free autologous fat obtained by blunt syringe suction lipectomy are unpredictable. We examined if adipose tissue viability is compromised by using syringe suction lipectomy and by infiltration of the tissue with loca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ecaf715e0a2aa0ed501af8630f4c47
https://doi.org/10.1007/bf00451659
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10
Effects of oleate and fatty acids from omental adipocytes on insulin uptake in rat liver cells
Autor: Guenther Boden, Jerzy W. Kolaczynski
Publikováno v: Endocrinology. 133:2871-2874
Hyperinsulinemia in central type (upper body) obesity has been related to reduced hepatic insulin uptake caused by fatty acids reaching the portal vein directly from the omental (visceral) fat depot. We investigated the effect of sodium oleate and fa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c617a894f3f789252d149caa80af9d3
https://doi.org/10.1210/endo.133.6.8243313
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