Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jerzy W, Łazarewicz"'
Autor:
Małgorzata, Duszczyk, Marcin, Gamdzyk, Apolonia, Ziembowicz, Paweł M, Boguszewski, Jerzy W, Łazarewicz, Elżbieta, Salińska
Publikováno v:
Acta neurobiologiae experimentalis. 75(4)
Previous studies have demonstrated that repeated submission of rats to mild hypobaric hypoxia reduces the persistent behavioral and hormonal depressive symptoms induced by exposure to footshock in the learned helplessness paradigm. The aim of this st
Publikováno v:
Folia neuropathologica. 53(4)
In the present study, we examined the effects of negative and positive allosteric modulators of metabotropic glutamate receptor 5 (mGluR5), fenobam and ADX47273, respectively, on brain damage induced by hypoxia-ischemia (H-I) in 7-day-old rats. The t
Publikováno v:
Pharmacological Reports. 64:1166-1178
Background Tetrabromobisphenol A (TBBPA) is a toxic brominated flame retardant. Previous studies have demonstrated that exposure of primary cultures of rat cerebellar granule cells (CGC) to ≥ 10 μM TBBPA induces toxicity and excitotoxicity, and th
Autor:
Magdalena Kuszczyk, Lucyna Antkiewicz-Michaluk, Jerzy W. Łazarewicz, Marta Słomka, Elzbieta Salinska
Publikováno v:
Pharmacological Reports. 62:1041-1050
The aim of this study was to establish the antagonistic effects of 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) on NMDA receptors and its neuroprotective abilities on primary cultures of rat cerebellar granule cells exposed for 30 min to 250 or 1
Publikováno v:
Pharmacological Reports. 62:440-443
Publikováno v:
Acta neurobiologiae experimentalis. 74(4)
Preconditioning is an experimental strategy for reducing ischemic brain damage. There are reports that brief exposure of neurons to NMDA-receptor antagonists may be an adequate preconditioning stressor. We studied effects of preconditioning of the ce
Autor:
Katarzyna Billing-Marczak, Wiesława Leśniak, Jerzy W. Łazarewicz, Elzbieta Zieminska, Jacek Kuźnicki
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1678:14-21
Calretinin (CR) is an EF-hand calcium binding protein expressed in a tissue-specific manner. CR gene is active in some neurons, such as cerebellar granule neurons and in some tumor cells such as colon adenocarcinoma or epithelial mesothelioma. Our ai
Autor:
Albert Teelken, Jaap Korf, Jan Albrecht, Stefan Bröer, Piet Eikelenboom, Antonio Guiditta, Jerzy W. Lazarewicz, Konrad Löffelholz, Rona R. Ramsey, Rupert Schmidt, Keith F. Tipton
Proceedings of the 11th European Society for Neurochemistry Meeting held in Groningen, The Netherlandes, June 15-20, 1996
Publikováno v:
Neurochemistry International. 43:273-278
Dantrolene is an inhibitor of a skeletal muscle subtype of ryanodine receptors that stabilizes intracellular calcium concentrations and exerts neuroprotective effects in neurons submitted to excitotoxic challenges. The mechanisms of dantrolene-induce
Publikováno v:
Pharmacological Reports. 67:8-9