Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Jerzy Boryski"'
Autor:
Dagmara Baraniak, Jerzy Boryski
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 628 (2021)
This review covers studies which exploit triazole-modified nucleic acids in the range of chemistry and biology to medicine. The 1,2,3-triazole unit, which is obtained via click chemistry approach, shows valuable and unique properties. For example, it
Externí odkaz:
https://doaj.org/article/1d38c62abe6e445dbf0224e45fc34c37
Autor:
Andrzej Manikowski, Daniel Baranowski, Joanna Fogt, Grzegorz Framski, Piotr Januszczyk, Zofia Jahnz-Wechmann, Dagmara Baraniak, Tomasz Ostrowski, Jerzy Boryski, Dariusz Wawrzyniak, Katarzyna Rolle
Publikováno v:
ChemistrySelect. 5:13370-13375
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::489c2266c7ce6b75f630cda5f948b4d0
https://doi.org/10.1002/slct.202003393
https://doi.org/10.1002/slct.202003393
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 38:980-1005
Two series of novel fluorinated nucleosides dimers with an unnatural 1,2,3-triazole linkage were synthesized. The obtained molecules were prepared using "click" chemistry approach based on copper(I) catalyzed Huisgen azide-alkyne cycloaddition. It wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1347f505a24434d92517e5df2d98f85a
https://doi.org/10.1080/15257770.2019.1641206
https://doi.org/10.1080/15257770.2019.1641206
Autor:
Maurycy Szlenkier, Jerzy Boryski
Publikováno v:
Current Organic Chemistry. 23:409-438
The nucleosides modified in the 2’- and/or 3’-position have been known for years and include important, bioactive compounds such as zidovudine, cytarabine, didanosine, puromycin, and fludarabine. This group consists of analogs with altered config
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b37fb9c14c6b09c510fca71fd22692b0
https://doi.org/10.2174/1385272823666190306155919
https://doi.org/10.2174/1385272823666190306155919
Autor:
Joanna Romanowska, Justyna Gołębiewska, Michal Sobkowski, Krystian Kolodziej, Tomasz Jakubowski, Marta Rachwalak, Jerzy Boryski, Aleksandra Dabrowska, Adam Kraszewski, Jacek Stawinski
Publikováno v:
European Journal of Medicinal Chemistry. 164:47-58
We have designed a new type of AZT and ddU phosphoramidate diesters containing various combinations of 2-, 3-, 4-aminopyridine and 2-, 3-, 4-hydroxypyridine moieties attached to the phosphorus center, as potential anti-HIV pronucleotides. Depending o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4708d049c559aac488e3aa03cb1d84f
https://doi.org/10.1016/j.ejmech.2018.12.038
https://doi.org/10.1016/j.ejmech.2018.12.038
Publikováno v:
Journal of Molecular Structure. 1250:131911
It was shown that in contrast to guanosine, its 7-regioisomer, 7-(β- d -ribofuranosyl)guanine, when subjected to reaction with methyl iodide in DMF containing sodium hydride, promoted the preferential formation of 3-substituted product, whereas 1-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca193aab86eea6fc2bb76cf5bb6694f4
https://doi.org/10.1016/j.molstruc.2021.131911
https://doi.org/10.1016/j.molstruc.2021.131911
Autor:
Jolanta Lisowiec-Wachnicka, Joanna Kosman, Anna Pasternak, Jerzy Boryski, Grzegorz Framski, Zofia Jahnz-Wechmann
Publikováno v:
Bioorganic Chemistry. 71:294-298
Herein, we present comprehensive physicochemical and structural analysis of various DNA hairpins modified with pyrrolo-2'-deoxycytidine (Py-dC) derivatives. The introduction of modified Py-dC in most cases causes minor decrease of hairpin thermodynam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c779154051580328415c193256d02b6
https://doi.org/10.1016/j.bioorg.2017.02.014
https://doi.org/10.1016/j.bioorg.2017.02.014
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 38(11)
The fluorinated nucleoside dimers with a 1,2,3-triazole linkage are novel compounds within the field of bioorganic chemistry. We report on the synthesis and properties of two groups of nucleoside dimers analogs possessing a different arrangement of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c95d03286f8775aa83340315e63d06a
https://pubmed.ncbi.nlm.nih.gov/31177919
https://pubmed.ncbi.nlm.nih.gov/31177919
Autor:
Jerzy Boryski, Dagmara Baraniak
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 628, p 628 (2021)
Biomedicines, Vol 9, Iss 628, p 628 (2021)
This review covers studies which exploit triazole-modified nucleic acids in the range of chemistry and biology to medicine. The 1,2,3-triazole unit, which is obtained via click chemistry approach, shows valuable and unique properties. For example, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac70e9c04d45ffb1ecad2196010280b6
https://doi.org/10.3390/biomedicines9060628
https://doi.org/10.3390/biomedicines9060628
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 35:410-425
Mitsunobu reaction of partially acylated uridine proceeds with high regioselectivity for intramolecular SN2 anhydro linkage closuring. Under the reaction conditions, an isomeric mixture of diacyl uridine derivatives with either free 2′- or 3′-hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714cccb004162b6afd3401d41884fc78
https://doi.org/10.1080/15257770.2016.1188943
https://doi.org/10.1080/15257770.2016.1188943