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Autor:
Robert, Plewa, Michał, Łuczak, Paweł, Burchardt, Andrzej, Bolewski, Jerzy, Wierzchowiecki, Tomasz, Siminiak
Publikováno v:
Kardiologia polska. 64(2)
Normally the N-terminal domain of the LDL receptor (LDLR) binds to low-density lipoprotein through apolipoprotein B100. Mutations within the LDL receptor and/or apolipoprotein B-100 genes compromising this process may lead to congenital monogenic hyp