Zobrazeno 1 - 10
of 603
pro vyhledávání: '"Jerzy, Adamski"'
Autor:
Hamidreza Raeisi-Dehkordi, Barbara Thorand, Sara Beigrezaei, Annette Peters, Wolfgang Rathman, Jerzy Adamski, Angeline Chatelan, Yvonne T. van der Schouw, Oscar H. Franco, Taulant Muka, Jana Nano
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Sex differences exist in type 2 diabetes (T2D), and androgens have been implicated in the etiology of T2D in a sex-specific manner. We therefore aimed to investigate whether androgens play a role in explaining sex differences in g
Externí odkaz:
https://doaj.org/article/924b8285d5314ae8a5c24bde2da692fd
Autor:
Anna Halama, Shaza Zaghlool, Gaurav Thareja, Sara Kader, Wadha Al Muftah, Marjonneke Mook-Kanamori, Hina Sarwath, Yasmin Ali Mohamoud, Nisha Stephan, Sabine Ameling, Maja Pucic Baković, Jan Krumsiek, Cornelia Prehn, Jerzy Adamski, Jochen M. Schwenk, Nele Friedrich, Uwe Völker, Manfred Wuhrer, Gordan Lauc, S. Hani Najafi-Shoushtari, Joel A. Malek, Johannes Graumann, Dennis Mook-Kanamori, Frank Schmidt, Karsten Suhre
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract In-depth multiomic phenotyping provides molecular insights into complex physiological processes and their pathologies. Here, we report on integrating 18 diverse deep molecular phenotyping (omics-) technologies applied to urine, blood, and sa
Externí odkaz:
https://doaj.org/article/711d016111244d3c97a32572e4aba254
Autor:
Makoto Harada, Jonathan Adam, Marcela Covic, Jianhong Ge, Stefan Brandmaier, Caroline Muschet, Jialing Huang, Siyu Han, Martina Rommel, Markus Rotter, Margit Heier, Robert P. Mohney, Jan Krumsiek, Gabi Kastenmüller, Wolfgang Rathmann, Zhongmei Zou, Sven Zukunft, Markus F. Scheerer, Susanne Neschen, Jerzy Adamski, Christian Gieger, Annette Peters, Donna P. Ankerst, Thomas Meitinger, Tanya L. Alderete, Martin Hrabe de Angelis, Karsten Suhre, Rui Wang-Sattler
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Metformin and sodium-glucose-cotransporter-2 inhibitors (SGLT2i) are cornerstone therapies for managing hyperglycemia in diabetes. However, their detailed impacts on metabolic processes, particularly within the citric acid (TCA) c
Externí odkaz:
https://doaj.org/article/5843fb532be04b438b4aad8078618b3c
Autor:
Juliane Maushagen, Nuha Shugaa Addin, Christopher Schuppert, Cavin K. Ward-Caviness, Johanna Nattenmüller, Jerzy Adamski, Annette Peters, Fabian Bamberg, Christopher L. Schlett, Rui Wang-Sattler, Susanne Rospleszcz
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Background Changes in serum metabolites in individuals with altered cardiac function and morphology may exhibit information about cardiovascular disease (CVD) pathway dysregulations and potential CVD risk factors. We aimed to explore associa
Externí odkaz:
https://doaj.org/article/b55762a40fb94dff85c72e5b75f9fecf
Autor:
Sharma, Sapna, Subrahmanyam, Yalamanchili Venkata, Ranjani, Harish, Sidra, Sidra, Parmar, Dharmeshkumar, Vadivel, Sangeetha, Kannan, Shanthini, Grallert, Harald, Usharani, Dandamudi, Anjana, Ranjit Mohan, Balasubramanyam, Muthuswamy, Mohan, Viswanathan, Jerzy, Adamski, Panchagnula, Venkateswarlu, Gokulakrishnan, Kuppan
Publikováno v:
In Nutrition, Metabolism and Cardiovascular Diseases July 2024 34(7):1807-1816
Autor:
Barbara Thorand, Annette Peters, Wolfgang Rathmann, Michael Roden, Christian Herder, Jerzy Adamski, Cornelia Prehn, Rui Wang-Sattler, Karsten Suhre, Jacqueline M Ratter-Rieck, Mengya Shi
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 12, Iss 2 (2024)
Introduction Circulating omentin levels have been positively associated with insulin sensitivity. Although a role for adiponectin in this relationship has been suggested, underlying mechanisms remain elusive. In order to reveal the relationship betwe
Externí odkaz:
https://doaj.org/article/24c47b4eeb7a49d8a33ed39a442f5c56
Autor:
Rhea Harewood, Joseph A. Rothwell, Jelena Bešević, Vivian Viallon, David Achaintre, Audrey Gicquiau, Sabina Rinaldi, Roland Wedekind, Cornelia Prehn, Jerzy Adamski, Julie A. Schmidt, Inarie Jacobs, Anne Tjønneland, Anja Olsen, Gianluca Severi, Rudolf Kaaks, Verena Katzke, Matthias B. Schulze, Marcela Prada, Giovanna Masala, Claudia Agnoli, Salvatore Panico, Carlotta Sacerdote, Paula Gabriela Jakszyn, Maria-Jose Sánchez, Jesús Castilla, María-Dolores Chirlaque, Amaia Aizpurua Atxega, Bethany van Guelpen, Alicia K. Heath, Keren Papier, Tammy Y.N. Tong, Scott A. Summers, Mary Playdon, Amanda J. Cross, Pekka Keski-Rahkonen, Véronique Chajès, Neil Murphy, Marc J. Gunter
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105024- (2024)
Summary: Background: Altered lipid metabolism is a hallmark of cancer development. However, the role of specific lipid metabolites in colorectal cancer development is uncertain. Methods: In a case–control study nested within the European Prospectiv
Externí odkaz:
https://doaj.org/article/db0b1c75776340c68fff5c55e1fdf881
Autor:
Sebastian Schmidt, Constantin Stautner, Duc Tung Vu, Alexander Heinz, Martin Regensburger, Ozge Karayel, Dietrich Trümbach, Anna Artati, Sabine Kaltenhäuser, Mohamed Zakaria Nassef, Sina Hembach, Letyfee Steinert, Beate Winner, Winkler Jürgen, Martin Jastroch, Malte D. Luecken, Fabian J. Theis, Gil Gregor Westmeyer, Jerzy Adamski, Matthias Mann, Karsten Hiller, Florian Giesert, Daniela M. Vogt Weisenhorn, Wolfgang Wurst
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract Sporadic Parkinson’s Disease (sPD) is a progressive neurodegenerative disorder caused by multiple genetic and environmental factors. Mitochondrial dysfunction is one contributing factor, but its role at different stages of disease progress
Externí odkaz:
https://doaj.org/article/221c463f9fd24a92948d727c0c8d5a38
Autor:
Andrew A. Brown, Juan J. Fernandez-Tajes, Mun-gwan Hong, Caroline A. Brorsson, Robert W. Koivula, David Davtian, Théo Dupuis, Ambra Sartori, Theodora-Dafni Michalettou, Ian M. Forgie, Jonathan Adam, Kristine H. Allin, Robert Caiazzo, Henna Cederberg, Federico De Masi, Petra J. M. Elders, Giuseppe N. Giordano, Mark Haid, Torben Hansen, Tue H. Hansen, Andrew T. Hattersley, Alison J. Heggie, Cédric Howald, Angus G. Jones, Tarja Kokkola, Markku Laakso, Anubha Mahajan, Andrea Mari, Timothy J. McDonald, Donna McEvoy, Miranda Mourby, Petra B. Musholt, Birgitte Nilsson, Francois Pattou, Deborah Penet, Violeta Raverdy, Martin Ridderstråle, Luciana Romano, Femke Rutters, Sapna Sharma, Harriet Teare, Leen ‘t Hart, Konstantinos D. Tsirigos, Jagadish Vangipurapu, Henrik Vestergaard, Søren Brunak, Paul W. Franks, Gary Frost, Harald Grallert, Bernd Jablonka, Mark I. McCarthy, Imre Pavo, Oluf Pedersen, Hartmut Ruetten, Mark Walker, The DIRECT Consortium, Jerzy Adamski, Jochen M. Schwenk, Ewan R. Pearson, Emmanouil T. Dermitzakis, Ana Viñuela
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract We evaluate the shared genetic regulation of mRNA molecules, proteins and metabolites derived from whole blood from 3029 human donors. We find abundant allelic heterogeneity, where multiple variants regulate a particular molecular phenotype,
Externí odkaz:
https://doaj.org/article/03b888dddec54ecd93647492ab5dd5aa
Autor:
Mengya Shi, Siyu Han, Kristin Klier, Gisela Fobo, Corinna Montrone, Shixiang Yu, Makoto Harada, Ann-Kristin Henning, Nele Friedrich, Martin Bahls, Marcus Dörr, Matthias Nauck, Henry Völzke, Georg Homuth, Hans J. Grabe, Cornelia Prehn, Jerzy Adamski, Karsten Suhre, Wolfgang Rathmann, Andreas Ruepp, Johannes Hertel, Annette Peters, Rui Wang-Sattler
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background Metabolic Syndrome (MetS) is characterized by risk factors such as abdominal obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C), hypertension, and hyperglycemia, which contribute to the development of
Externí odkaz:
https://doaj.org/article/ae77aba3a99a49d3bf080ee8cff128b9