Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jeryl Hauptman"'
Autor:
Lei Chen, Anweshan Samanta, Lin Zhao, Nathaniel R. Dudley, Tanner Buehler, Robert J. Vincent, Jeryl Hauptman, Magdy Girgis, Buddhadeb Dawn
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102272- (2021)
Summary: Although vitamin D3 (VitD3) prevents angiogenesis in cancer, VitD3 deficiency is associated with greater incidence of cardiovascular events in patients. We examined the influence of VitD3 on the angiogenic potential of mesenchymal stem cells
Externí odkaz:
https://doaj.org/article/0ebcb5869a2f4021b83c3b0a3df8a458
Autor:
Melissa S. Cobb, Shixin Tao, Katherine Shortt, Magdy Girgis, Jeryl Hauptman, Jill Schriewer, Zaphrirah Chin, Edward Dorfman, Kyle Campbell, Daniel P. Heruth, Ralph V. Shohet, Buddhadeb Dawn, Eugene A. Konorev
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H1091-H1107
Many anticancer therapies cause serious cardiovascular complications that degrade quality of life and cause early mortality in treated patients. Specifically, doxorubicin is known as an effective anticancer agent that causes cardiomyopathy in treated
Autor:
Magdy Girgis, Michael J Wulser, Lin Zhao, Matt De Ruyter, Anweshan Samanta, Buddhadeb Dawn, Kashyap Choksi, Patrick McEnulty, Jeryl Hauptman, Robert J. Vincent, Rupal Soder, Yanjuan Yang, Carl P. Weiner, Guangming Cheng
Publikováno v:
Circulation Research. 125:759-772
Rationale: Human umbilical cord blood (hUCB) contains diverse populations of stem/progenitor cells. Whether hUCB-derived nonhematopoietic cells would induce cardiac repair remains unknown. Objective: To examine whether intramyocardial transplantation
Autor:
Nathaniel R. Dudley, Magdy Girgis, Lei Chen, Buddhadeb Dawn, Robert J. Vincent, Anweshan Samanta, Jeryl Hauptman, Lin Zhao, Tanner Buehler
Publikováno v:
iScience
iScience, Vol 24, Iss 4, Pp 102272-(2021)
iScience, Vol 24, Iss 4, Pp 102272-(2021)
Summary Although vitamin D3 (VitD3) prevents angiogenesis in cancer, VitD3 deficiency is associated with greater incidence of cardiovascular events in patients. We examined the influence of VitD3 on the angiogenic potential of mesenchymal stem cells
Autor:
Buddhadeb Dawn, Runming Jin, Arash Davani, Lei Chen, Yanjuan Yang, Xing Chen, Magdy Girgis, Robert J. Vincent, Guangming Cheng, Yanqing Zhu, Ou-Li Wang, Jeryl Hauptman, Lin Zhao, Anweshan Samanta, Harold Elias, Yu-Ting Xuan, Muhammad R. Afzal, Sheng Ye
Publikováno v:
Circulation research. 118(12)
Rationale: The role of interleukin (IL)-6 in the pathogenesis of cardiac myocyte hypertrophy remains controversial. Objective: To conclusively determine whether IL-6 signaling is essential for the development of pressure overload–induced left ventr
Autor:
Jeryl Hauptman, Sylwia Kedracka-Krok, Elżbieta Karnas, Yu-Ting Xuan, Michal Sarna, Zbigniew Madeja, Arash Davani, Anna Labedz-Maslowska, Yanjuan Yang, Magdy Girgis, Ewa K. Zuba-Surma, Anweshan Samanta, Robert J. Vincent, Buddhadeb Dawn, Ou-Li Wang, Dominika Berdecka, Guangming Cheng
Publikováno v:
Circulation. 132
Introduction: Stem cell-derived extracellular vesicles (EVs) are known to facilitate cell-to-cell communication. The potential of mesenchymal stem cell (MSC)-derived EVs for cardiac repair when compared with MSC whole cell injection remains unknown.
Autor:
Runming Jin, Patrick McEnulty, Rizwan Afzal, Buddhadeb Dawn, Yanjuan Yang, Guangming Cheng, Samuel Asante, Lin Zhao, Robert J. Vincent, Anweshan Samanta, Magdy Girgis, Sheng Ye, Jeryl Hauptman, Xing Chen
Publikováno v:
Circulation. 132
Introduction: Interleukin-6 (IL-6), a proinflammatory cytokine, has been implicated in ischemic cardiac pathologies. Very little is currently known regarding the role of IL-6 signaling in pathological cardiomyocyte hypertrophy and LV dysfunction. Hyp
Autor:
Guangming Cheng, Sheng Ye, Magdy Girgis, Lin Zhao, Xing Chen, Anweshan Samanta, Yanjuan Yang, Jeryl Hauptman, Robert Vincent, Buddhadeb Dawn
Publikováno v:
Circulation. 132
Introduction: Emerging evidence indicates that myocardial ischemia/reperfusion (I/R) injury is more severe in aged hearts. Although nuclear factor-kappaB (NF-kB) activity increases with aging, whether this redox-responsive transcription factor plays
Autor:
Kashyap Choksi, Yanjuan Yang, Anweshan Samanta, Arash Davani, Lin Zhao, Jeryl Hauptman, Guangming Cheng, Magdy Girgis, Amy Cantilena, Buddhadeb Dawn, Harold Elias, Robert J. Vincent, Lei Chen
Publikováno v:
Journal of the American College of Cardiology. 65(10)
The molecular details of nuclear factor-kappaB (NF-kB) signaling during myocardial ischemia/reperfusion (I/R) injury remain poorly understood. We hypothesized that inhibition of NF-kB would prevent cell death. We used transgenic mice overexpressing a
Autor:
Magdy Girgis, Kashyap Choksi, Jeryl Hauptman, Yanjuan Yang, Lin Zhao, Buddhadeb Dawn, Runming Jin, Anweshan Samanta, Lei Chen, Robert J. Vincent, Harold Elias, Arash Davani, Guangming Cheng
Publikováno v:
Circulation. 130
Introduction: The necessity of IL-6 signaling in pressure overload-induced left ventricular hypertrophy remains controversial. Whether Calcium/calmodulin-dependent kinase II (CaMKII) participates in IL-6-induced and pressure overload-induced hypertro