Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jervis Vermal Thevathasan"'
Autor:
Sara Elfarrash, Nanna Møller Jensen, Nelson Ferreira, Cristine Betzer, Jervis Vermal Thevathasan, Robin Diekmann, Mohamed Adel, Nisreen Mansour Omar, Mohamed Z. Boraie, Sabry Gad, Jonas Ries, Deniz Kirik, Sadegh Nabavi, Poul Henning Jensen
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Here we describe the use of an organotypic hippocampal slice model for studying α-synuclein aggregation and inter-neuronal spreading initiated by microinjection of pre-formed α-synuclein fibrils (PFFs). PFF injection at dentate gyrus (DG)
Externí odkaz:
https://doaj.org/article/10fb2dc993f841539e1e8dae921a245c
Autor:
Katia Cosentino, Vanessa Hertlein, Andreas Jenner, Timo Dellmann, Milos Gojkovic, Aida Peña-Blanco, Shashank Dadsena, Noel Wajngarten, John S.H. Danial, Jervis Vermal Thevathasan, Markus Mund, Jonas Ries, Ana J. Garcia-Saez
Publikováno v:
Molecular Cell. 82:933-949.e9
BAX and BAK are key apoptosis regulators that mediate the decisive step of mitochondrial outer membrane permeabilization. However, the mechanism by which they assemble the apoptotic pore remains obscure. Here, we report that BAX and BAK present disti
Autor:
Jonas Ries, Elena Buglakova, Yongdeng Zhang, Jervis Vermal Thevathasan, Yiming Li, Joerg Bewersdorf
Publikováno v:
Optics letters. 45(13)
Interferometric single-molecule localization microscopy (iPALM, 4Pi-SMS) uses multiphase interferometry to localize single fluorophores and achieves nanometer isotropic resolution in 3D. The current data analysis workflow, however, fails to reach the
Autor:
Mohamed Z. Boraie, Sabry Gad, Sara Elfarrash, Robin Diekmann, Nanna Møller Jensen, Nisreen Mansour Omar, Sadegh Nabavi, Deniz Kirik, Poul Henning Jensen, Jervis Vermal Thevathasan, Cristine Betzer, Nelson Ferreira, Jonas Ries, Mohamed Adel
Here we describe the use of an organotypic hippocampal slice model for studying α-synuclein aggregation and inter-neuronal spreading initiated by injection of preformed α-synuclein filaments (PFFs). PFF injection at dentate gyrus templates the endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e411250dad40dc8b596c1fd65babc138
https://doi.org/10.1101/681064
https://doi.org/10.1101/681064
Autor:
Daniel Heid, Konstanty Cieśliński, Maurice Kahnwald, Markus Mund, Yu-Le Wu, Ulf Matti, Philipp Hoess, Jan Ellenberg, Sudheer Kumar Peneti, Sarah Janice Hoerner, Ricardo Henriques, Vilma Jimenez Sabinina, Yiming Li, Pedro M. Pereira, Krishna Chaitanya Kasuba, Jervis Vermal Thevathasan, Bianca Nijmeijer, Moritz Kueblbeck, Manuel Reitberger, Jonas Ries
Publikováno v:
Nature methods
Nature Methods
Nature Methods
Quantitative fluorescence and superresolution microscopy are often limited by insufficient data quality or artifacts. In this context, it is essential to have biologically relevant control samples to benchmark and optimize the quality of microscopes,
Publikováno v:
Biophysical Journal. 118:150a
Autor:
Loo Chin Wong, Bo Lu, Jervis Vermal Thevathasan, Lynette Lim, Fang Ji, Willcyn Tang, Kenrick An Fu Yap, Marc Fivaz, George J. Augustine, Shou Yu Poon, James J. Mancuso, Gisela Garcia-Alvarez, Kia Wee Tan
Publikováno v:
Molecular Biology of the Cell
STIMs (STIM1 and STIM2 in mammals) are transmembrane proteins that reside in the endoplasmic reticulum and regulate store-operated Ca2+ entry. STIM2 mediates cAMP/PKA-dependent phosphorylation of the AMPA receptor subunit GluA1 in excitatory neurons.
Autor:
Sudheer Kumar Peneti, Ulf Matti, Sarah Janice Hoerner, Daniel Heid, Krishna Chaitanya Kasuba, Yiming Li, Jan Ellenberg, Yu-Le Wu, Markus Mund, Vilma Jimenez Sabinina, Manuel Reitberger, Jonas Ries, Ricardo Henriques, Moritz Kueblbeck, Philipp Hoess, Jervis Vermal Thevathasan, Konstanty Cieśliński, Maurice Kahnwald, Pedro M. Pereira, Bianca Nijmeijer
Publikováno v:
Nature Methods. 16:1332-1332
Autor:
Bianca Nijmeijer, Moritz Kueblbeck, Jonas Ries, Maurice Kahnwald, Jervis Vermal Thevathasan, Sudheer Kumar Peneti, Ulf Matti, Jan Ellenberg
Publikováno v:
Biophysical Journal. 116:137a
Autor:
Takanari Inoue, Marc Fivaz, Elisabeth Tan, Yu-Chun Lin, Hui Zheng, Yang Li, Jervis Vermal Thevathasan
Publikováno v:
Molecular Biology of the Cell
An inducible activation approach is used to interrogate the positive feedback circuit underlying self-amplification of PI3K signals in fibroblasts. The results show that local positive feedback between PI3K and HRas drives asymmetric membrane extensi