Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Jerson L Silva"'
Autor:
Ana C Vicente Santos, Francisca H Guedes-da-Silva, Carlos H Dumard, Vivian N S Ferreira, Igor P S da Costa, Ruana A Machado, Fernanda G Q Barros-Aragão, Rômulo L S Neris, Júlio S Dos-Santos, Iranaia Assunção-Miranda, Claudia P Figueiredo, André A Dias, Andre M O Gomes, Herbert L de Matos Guedes, Andrea C Oliveira, Jerson L Silva
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009907 (2021)
Zika virus (ZIKV) emerged as an important infectious disease agent in Brazil in 2016. Infection usually leads to mild symptoms, but severe congenital neurological disorders and Guillain-Barré syndrome have been reported following ZIKV exposure. Crea
Externí odkaz:
https://doaj.org/article/9a0c189268f04faf98a26350189d234f
Autor:
Elaine C. Petronilho, Guilherme C. de Andrade, Gileno dos S. de Sousa, Fernando P. Almeida, Michelle F. Mota, Ana Vitória dos S. Gomes, Carlos Henrique S. Pinheiro, Mylena C. da Silva, Hiam R. S. Arruda, Mayra A. Marques, Tuane C. R. G. Vieira, Guilherme A. P. de Oliveira, Jerson L. Silva
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract P53 Phase separation is crucial towards amyloid aggregation and p63 and p73 have enhanced expression in tumors. This study examines the phase behaviors of p53, p63, and p73. Here we show that unlike the DNA-binding domain of p53 (p53C), the
Externí odkaz:
https://doaj.org/article/00b9e9a826c54afface84a0c4a7613a7
Autor:
Shana P C Barroso, Dirlei Nico, Danielle Nascimento, Ana Clara V Santos, José Nelson S S Couceiro, Fernando A Bozza, Ana M A Ferreira, Davis F Ferreira, Clarisa B Palatnik-de-Sousa, Thiago Moreno L Souza, Andre M O Gomes, Jerson L Silva, Andréa C Oliveira
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128785 (2015)
Influenza viruses pose a serious global health threat, particularly in light of newly emerging strains, such as the avian influenza H5N1 and H7N9 viruses. Vaccination remains the primary method for preventing acquiring influenza or for avoiding devel
Externí odkaz:
https://doaj.org/article/7f5ad3ffd0f04afaa535ddbd25844250
Autor:
Carlos H Dumard, Shana P C Barroso, Guilherme A P de Oliveira, Carlos A M Carvalho, Andre M O Gomes, José Nelson S S Couceiro, Davis F Ferreira, Dirlei Nico, Andrea C Oliveira, Jerson L Silva, Patrícia S Santos
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80785 (2013)
Whole inactivated vaccines (WIVs) possess greater immunogenicity than split or subunit vaccines, and recent studies have demonstrated that WIVs with preserved fusogenic activity are more protective than non-fusogenic WIVs. In this work, we describe t
Externí odkaz:
https://doaj.org/article/69e65d813b2749b885bd2a31fe2d950f
Autor:
Guilherme A P de Oliveira, Elen G Pereira, Cristiano V Dias, Theo L F Souza, Giulia D S Ferretti, Yraima Cordeiro, Luciana R Camillo, Júlio Cascardo, Fabio C Almeida, Ana Paula Valente, Jerson L Silva
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45620 (2012)
Understanding how Nep-like proteins (NLPs) behave during the cell cycle and disease progression of plant pathogenic oomycetes, fungi and bacteria is crucial in light of compelling evidence that these proteins play a role in Witches` Broom Disease (WB
Externí odkaz:
https://doaj.org/article/e641c1d137a148f7a8cde28acf660d79
Autor:
Danielly Cristiny Ferraz da Costa, Fabiana Alves Casanova, Julia Quarti, Maitê Santos Malheiros, Daniel Sanches, Patricia Souza Dos Santos, Eliane Fialho, Jerson L Silva
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48746 (2012)
Resveratrol is a promising chemopreventive agent that mediates many cellular targets involved in cancer signaling pathways. p53 has been suggested to play a role in the anticancer properties of resveratrol. We investigated resveratrol-induced cytotox
Externí odkaz:
https://doaj.org/article/1d53d1c290824d9ab0bf0445af6301fd
Autor:
Ygara S Mendes, Nathalia S Alves, Theo L F Souza, Ivanildo P Sousa, M Lucia Bianconi, Rafael C Bernardi, Pedro G Pascutti, Jerson L Silva, Andre M O Gomes, Andréa C Oliveira
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47596 (2012)
Membrane fusion is a crucial step in flavivirus infections and a potential target for antiviral strategies. Lipids and proteins play cooperative roles in the fusion process, which is triggered by the acidic pH inside the endosome. This acidic environ
Externí odkaz:
https://doaj.org/article/72f63a16f0964dbbaf8d963d84a04b4c
Autor:
Mônica S Freitas, Cristian Follmer, Lilian T Costa, Cecília Vilani, M Lucia Bianconi, Carlos Alberto Achete, Jerson L Silva
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15756 (2011)
The Ebola fusion peptide (EBO₁₆) is a hydrophobic domain that belongs to the GP2 membrane fusion protein of the Ebola virus. It adopts a helical structure in the presence of mimetic membranes that is stabilized by the presence of an aromatic-arom
Externí odkaz:
https://doaj.org/article/54091954e00c4f799a03b4300ed887ab
Autor:
Mariana M. Paz, Giulia D. S. Ferretti, Mafalda M. C. Martins-Dinis, Beatriz I. S. Ferreira, Amanda Faier-Pereira, Thibaut Barnoud, Otacilio C. Moreira, Jerson L. Silva, Yraima Cordeiro, Luciana P. Rangel
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Although many therapeutic options are available, several factors, including the presence of p53 mutations, impact tumor development and therapeutic resistan
Externí odkaz:
https://doaj.org/article/a63a21b730f141c89ca914e08c92a1d4
Autor:
Fabricia L. Fontes-Dantas, Gabriel G. Fernandes, Elisa G. Gutman, Emanuelle V. De Lima, Leticia S. Antonio, Mariana B. Hammerle, Hannah P. Mota-Araujo, Lilian C. Colodeti, Suzana M.B. Araújo, Gabrielle M. Froz, Talita N. da Silva, Larissa A. Duarte, Andreza L. Salvio, Karina L. Pires, Luciane A.A. Leon, Claudia Cristina F. Vasconcelos, Luciana Romão, Luiz Eduardo B. Savio, Jerson L. Silva, Robson da Costa, Julia R. Clarke, Andrea T. Da Poian, Soniza V. Alves-Leon, Giselle F. Passos, Claudia P. Figueiredo
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112189- (2023)
Summary: Cognitive dysfunction is often reported in patients with post-coronavirus disease 2019 (COVID-19) syndrome, but its underlying mechanisms are not completely understood. Evidence suggests that severe acute respiratory syndrome coronavirus 2 (
Externí odkaz:
https://doaj.org/article/fe134363e486421c960c5fd3b4c479bc