Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Jerry W. Simecka"'
Autor:
Gregory P. Howard, Nicole G. Bender, Prachi Khare, Borja López-Gutiérrez, Vincent Nyasembe, William J. Weiss, Jerry W. Simecka, Timothy Hamerly, Hai-Quan Mao, Rhoel R. Dinglasan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A successful malaria transmission blocking vaccine (TBV) requires the induction of a high antibody titer that leads to abrogation of parasite traversal of the mosquito midgut following ingestion of an infectious bloodmeal, thereby blocking the cascad
Externí odkaz:
https://doaj.org/article/b57a063ffd7d4e87aa007842f02ce0da
Autor:
Adam N Odeh, Jerry W Simecka
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155648 (2016)
Mycoplasmas cause respiratory diseases characterized by persistent infection and chronic airway inflammation. Mycoplasma lung disease is immunopathologic, with CD4+ Th cells determining both disease severity and resistance to infection. Th2 cell resp
Externí odkaz:
https://doaj.org/article/c8f497ec1be54c07b2506702fe56476f
Autor:
Sangram Raut, W. Paul Bowman, Anish Ray, Jerry W. Simecka, Riyaz Basha, Don Eslin, Umesh T. Sankpal, Sagar Shelake
Publikováno v:
Apoptosis. 24:21-32
OBJECTIVE: Current therapeutic strategies used in Ewing sarcoma (ES) especially for relapsed patients have resulted in modest improvements in survival over the past 20 years. Combination therapeutic approach presents as an alternative to overcoming d
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55984 (2013)
Mycoplasmas cause chronic respiratory diseases in animals and humans, and to date, development of vaccines have been problematic. Using a murine model of mycoplasma pneumonia, lymphocyte responses, specifically T cells, were shown to confer protectio
Externí odkaz:
https://doaj.org/article/c1dea3c9d19849498cf422e51475133d
Autor:
Fiona Maunsell, Mary B Brown, Joshua Powe, James Ivey, Matthew Woolard, Wees Love, Jerry W Simecka
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44523 (2012)
Because M. bovis otitis media is an economically important problem, there is a need to understand the pathogenesis of disease, not only to improve our understanding of the factors contributing to the development of this disease but also to inform the
Externí odkaz:
https://doaj.org/article/5a0c664121f24245b494c20a7d0d2d8a
Publikováno v:
BMC Microbiology
BMC Microbiology, Vol 20, Iss 1, Pp 1-14 (2020)
BMC Microbiology, Vol 20, Iss 1, Pp 1-14 (2020)
Background. Clostridium difficile infections have become more frequently diagnosed and associated with greater disease severity, which has resulted in an increase burden on the healthcare system. These increases are attributed to the increased preval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fa01189e48c2e65530c68602251fbf
https://doi.org/10.21203/rs.2.15921/v2
https://doi.org/10.21203/rs.2.15921/v2
Autor:
Patrick D Olson, Lisa J Kuechenmeister, Kelsi L Anderson, Sonja Daily, Karen E Beenken, Christelle M Roux, Michelle L Reniere, Tami L Lewis, William J Weiss, Mark Pulse, Phung Nguyen, Jerry W Simecka, John M Morrison, Khalid Sayood, Oluwatoyin A Asojo, Mark S Smeltzer, Eric P Skaar, Paul M Dunman
Publikováno v:
PLoS Pathogens, Vol 7, Iss 2, p e1001287 (2011)
Methicillin-resistant Staphylococcus aureus is estimated to cause more U.S. deaths annually than HIV/AIDS. The emergence of hypervirulent and multidrug-resistant strains has further amplified public health concern and accentuated the need for new cla
Externí odkaz:
https://doaj.org/article/78e41f54ca3e43d185ba27c4529fcda9
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10739 (2010)
Mycoplasma lipoproteins are recognized by Toll-like receptors (TLR), but TLRs' role in responses to infection are unknown. Mycoplasma pulmonis is a naturally occurring respiratory pathogen in mice. In the current study, we used TLR-transfected HEK ce
Externí odkaz:
https://doaj.org/article/9138038b8915415ca5563ab41645a581
Autor:
Jerry W. Simecka, Frank Filipetto, Joon-Hak Lee, Patricia A. Taylor, John C Vitucci, Anna Espinoza, Sushma Sharma, Mark Pulse, Phung Nguyen, Kimberly G. Fulda
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0220646 (2019)
PLoS ONE, Vol 14, Iss 8, p e0220646 (2019)
C. difficile is an endospore-forming pathogen, which is becoming a common cause of microbial health-care associated gastrointestinal disease in the United States. Both healthy and symptomatic patients can shed C. difficile spores into the environment
Publikováno v:
Archives of Microbiology & Immunology.
Between 2000-2007, Clostridium (now Closteroides) difficile infections have increased by a factor of 400% and have been associated with greater disease severity. These increases are associated to the increased prevalence of the NAP1/BI/027 ribotype (