Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Jerry Vriend"'
Autor:
Jerry Vriend, Xiao-Qing Liu
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7506 (2024)
Survival of Medulloblastoma (MB) depends on various factors, including the gene expression profiles of MB tumor tissues. In this study, we identified 967 MB survival-related genes (SRGs) using a gene expression dataset and the Cox proportional hazard
Externí odkaz:
https://doaj.org/article/dd0b274659aa46b58c2ba83f046d99d2
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1503 (2023)
The ubiquitin proteasome system (UPS) utilizes an orchestrated enzymatic cascade of E1, E2, and E3 ligases to add single or multiple ubiquitin-like molecules as post-translational modification (PTM) to proteins. Ubiquitination can alter protein funct
Externí odkaz:
https://doaj.org/article/14a69a1ffa9b4fedabec529787c8d576
Autor:
Jerry Vriend
Publikováno v:
Cancers, Vol 15, Iss 13, p 3460 (2023)
The ubiquitin proteasome system regulates the activity of many short-lived proteins in cells [...]
Externí odkaz:
https://doaj.org/article/85ac9204943b465db7505dc58c1d2713
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12330 (2022)
The ubiquitin proteasome system (UPS) is critically important for cellular homeostasis and affects virtually all key functions in normal and neoplastic cells. Currently, a comprehensive review of the role of the UPS in ependymoma (EPN) brain tumors i
Externí odkaz:
https://doaj.org/article/4032f5673faa4565951536b15480fe44
Autor:
Jerry Vriend, Mark W. Nachtigal
Publikováno v:
Cancers, Vol 13, Iss 11, p 2659 (2021)
In this article, we reviewed the transcription of genes coding for components of the ubiquitin proteasome pathway in publicly available datasets of epithelial ovarian cancer (EOC). KEGG analysis was used to identify the major pathways distinguishing
Externí odkaz:
https://doaj.org/article/0abfd935eb9d4c47a1062510f3078dca
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172441 (2017)
A recent study of the pineal gland of the rat found that the expression of more than 3000 genes showed significant day/night variations (The Hartley dataset). The investigators of this report made available a supplemental table in which they tabulate
Externí odkaz:
https://doaj.org/article/48858abbc9364cf7bb1ff20a090fb4da
Autor:
Jerry Vriend, Thomas Klonisch
Publikováno v:
Cellular and Molecular Neurobiology. 43:1425-1452
We have mined public genomic datasets to identify genes coding for components of the ubiquitin proteasome system (UPS) that may qualify as potential diagnostic and therapeutic targets in the three major glioma types, astrocytoma (AS), glioblastoma (G
Autor:
Jerry Vriend, Xiaodan Jiao
Publikováno v:
Contemporary Clinical Neuroscience ISBN: 9783031231032
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4ebdcd3e09a58091dcda9760fb462da
https://doi.org/10.1007/978-3-031-23104-9_12
https://doi.org/10.1007/978-3-031-23104-9_12
Autor:
Mark W. Nachtigal, Jerry Vriend
Publikováno v:
Cancers, Vol 13, Iss 2659, p 2659 (2021)
Cancers
Cancers
Simple Summary In this review, public datasets were mined in an attempt to identify genes that code for proteins of the ubiquitin proteasome system that can be used as therapeutic targets in high-grade serous ovarian cancer. In this study, we found t
Autor:
Robert B. Tate, Jerry Vriend
Publikováno v:
The Cerebellum. 18:469-488
Using publically available datasets on gene expression in medulloblastoma (MB) subtypes, we selected genes for ubiquitin ligases and identified statistically those that best predicted each of the four major MB subgroups as separate disease entities.