Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jerry Tso"'
Autor:
Evelyn Yanez, Joseph W. Lubach, Daniel P. Dobson, Jackson D. Pellet, Andreas Stumpf, Jerry Tso
Publikováno v:
Journal of Pharmaceutical Sciences. 110:3037-3046
Micronization by air jet milling is often used to produce drug substance particles of acceptable respirable size for use in dry powder inhaler formulations. The energy from this process often induces surface disordered sites on the micronized particl
Autor:
Francis Gosselin, Jie Xu, Rémy Angelaud, Brandon Scott, Lauren E. Sirois, Sushant Malhotra, David Lao, Paroma Chakravarty, Jerry Tso
Publikováno v:
Organic Process Research & Development. 24:567-578
Process development for a multi-kilogram-scale synthesis of GDC-0022, an inhibitor of retinoic acid receptor-related orphan receptor γ (RORc), is described. Delivery of the active pharmaceutical in...
Autor:
Virender Kumar, Bharti Sethi, Evelyn Yanez, Dennis H. Leung, Yashwardhan Y. Ghanwatkar, Jonathan Cheong, Jerry Tso, Ajit S. Narang, Karthik Nagapudi, Ram I. Mahato
Publikováno v:
International journal of pharmaceutics. 615
In this study, we evaluated the aerodynamic performance, dissolution, and permeation behavior of micronized fluticasone propionate (FP) and magnesium stearate (MgSt) binary mixtures. Micronized FP was dry mixed with 2% w/w MgSt using a tumble mixer a
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 148:93-99
A gas chromatographic procedure has been developed for the trace determination of chloroacetyl chloride (CAC) and two of its impurities: methyl chloroacetate (MCA) and chloroacetic acid (CAA). All three compounds are derivatized using piperidine in d
Publikováno v:
International Journal of Pharmaceutics. 583:119404
Pulmonary drug delivery is a non-invasive and effective route for local or systemic drug administration. Despite several products in the market, the mechanism of drug absorption from the lungs is not well understood. An in vitro model for aerosol dep
Publikováno v:
JAWRA Journal of the American Water Resources Association. 48:558-569
Dutta, Sudarshan, Shreeram Inamdar, Jerry Tso, Diana S. Aga, and J. Tom Sims, 2012. Dissolved Organic Carbon and Estrogen Transport in Surface Runoff from Agricultural Land Receiving Poultry Litter. Journal of the American Water Resources Association
Publikováno v:
Water, Air, & Soil Pollution. 223:2821-2836
Animal hormones can enter the aquatic environment along with runoff as a result of manure or litter application on agricultural landscapes. Our understanding of the transport of these hormones and their concentrations at various points along the wate
Autor:
Diana S. Aga, Jerry Tso
Publikováno v:
Analytical Chemistry. 83:269-277
The increasing demand to monitor multiple classes of analytes has been mirrored by increased analytical cost and decreased throughput. For instance, the analyses of estrogens and antibiotics by liquid chromatography with tandem mass spectrometry (LC-
Publikováno v:
Journal of Environmental Quality. 39:1688-1698
Land application of animal manures such as poultry litter is a common practice, especially in states with surplus manure. Past studies have shown that animal manure may contain estrogens, which are classified as endocrine-disrupting chemicals and may
Publikováno v:
Journal of agricultural and food chemistry. 59(6)
The ability to monitor multiple analytes from various classes of compounds in a single analysis can increase throughput and reduce cost when compared to traditional methods of analyses. This method for analyzing free (parent estrogen) and conjugated