Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Jerry S Wolinsky"'
Autor:
Benjamin C. Musall, Refaat E. Gabr, Yanyu Yang, Arash Kamali, John A. Lincoln, Michael A. Jacobs, Vi Ly, Xi Luo, Jerry S. Wolinsky, Ponnada A. Narayana, Khader M. Hasan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In addition to focal lesions, diffusely abnormal white matter (DAWM) is seen on brain MRI of multiple sclerosis (MS) patients and may represent early or distinct disease processes. The role of MRI-observed DAWM is understudied due to a lack
Externí odkaz:
https://doaj.org/article/3e128226b2504bf594fffba5f66cd26e
Autor:
Kaarina Kowalec, Arvid Harder, Casandra Dolovich, Kathryn C. Fitzgerald, Amber Salter, Yi Lu, Charles N. Bernstein, James M. Bolton, Gary Cutter, John D. Fisk, Joel Gelernter, Lesley A. Graff, Sara Hägg, Carol A. Hitchon, Daniel F. Levey, Fred D. Lublin, Kyla A. McKay, Scott Patten, Amit Patki, Murray B. Stein, Hemant K. Tiwari, Jerry S. Wolinsky, Ruth A. Marrie
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 6, Pp 1393-1404 (2024)
Abstract Objective Comorbid anxiety occurs often in MS and is associated with disability progression. Polygenic scores offer a possible means of anxiety risk prediction but often have not been validated outside the original discovery population. We a
Externí odkaz:
https://doaj.org/article/44eb7cddf85b402196eae2d92bb7367c
Autor:
Sammita Satyanarayan, Gary Cutter, Stephen Krieger, Stacey Cofield, Jerry S Wolinsky, Fred Lublin
Publikováno v:
Multiple Sclerosis Journal. 29:568-575
Background: Definitions of trial measures are consequential to accurately capturing outcomes and cross-trial comparability, particularly for derivative measures. Objective: Using CombiRx, examine the impact of relapse definition on endpoints and eval
Autor:
Douglas L Arnold, Till Sprenger, Amit Bar-Or, Jerry S Wolinsky, Ludwig Kappos, Shannon Kolind, Ulrike Bonati, Stefano Magon, Johan van Beek, Harold Koendgen, Oscar Bortolami, Corrado Bernasconi, Laura Gaetano, Anthony Traboulsee
Publikováno v:
Multiple Sclerosis Journal. 28:1927-1936
Background: In multiple sclerosis (MS), thalamic integrity is affected directly by demyelination and neuronal loss, and indirectly by gray/white matter lesions outside the thalamus, altering thalamic neuronal projections. Objective: To assess the eff
Autor:
Xavier Montalban, Jerry S. Wolinsky, Douglas L. Arnold, Martin S. Weber, Karolina Piasecka-Stryczynska, Davorka Tomic, Andrea Seitzinger, Hans Guehring
Publikováno v:
Monday, April 24.
Publikováno v:
J Neuroimaging
BACKGROUND AND PURPOSE: Changes in cerebral perfusion occur early in relapsing and progressive multiple sclerosis (MS) patients though whether cerebral blood flow (CBF) can be altered by therapy is unknown. We sought to characterize the time course o
Autor:
Gary Cutter, Marcus W. Koch, Jerry S. Wolinsky, Fred D. Lublin, Bernard M. J. Uitdehaag, Jop P. Mostert
Publikováno v:
Neurology
Background and ObjectivesClinical trials in relapsing-remitting multiple sclerosis (RRMS) usually use the Expanded Disability Status Scale (EDSS) as their primary disability outcome measure, while the more recently developed outcomes timed 25-ft walk
Autor:
Gary Cutter, Marcus W. Koch, Jerry S. Wolinsky, Yinan Zhang, Eva Strijbis, Jop P. Mostert, Fred D. Lublin
Publikováno v:
Neurology, 97(13), e1334-e1342. Lippincott Williams and Wilkins
Neurology
Koch, M W, Mostert, J, Zhang, Y, Wolinsky, J S, Lublin, F D, Strijbis, E & Cutter, G 2021, ' Association of Age With Contrast-Enhancing Lesions Across the Multiple Sclerosis Disease Spectrum ', Neurology, vol. 97, no. 13, pp. e1334-e1342 . https://doi.org/10.1212/WNL.0000000000012603
Neurology
Koch, M W, Mostert, J, Zhang, Y, Wolinsky, J S, Lublin, F D, Strijbis, E & Cutter, G 2021, ' Association of Age With Contrast-Enhancing Lesions Across the Multiple Sclerosis Disease Spectrum ', Neurology, vol. 97, no. 13, pp. e1334-e1342 . https://doi.org/10.1212/WNL.0000000000012603
Background and ObjectivesTo investigate the association of age and the presence of contrast-enhancing lesions (CELs) on cranial MRI scans in different disease courses of multiple sclerosis (MS), we describe the frequency of CELs as a function of age
Publikováno v:
Multiple Sclerosis and Related Disorders. 74:104727
Association of Vitamin D Polygenic Risk Scores and Disease Outcome in People With Multiple Sclerosis
Autor:
Eleni S. Vasileiou, Chen Hu, Charles N. Bernstein, Fred Lublin, Jerry S. Wolinsky, Gary R. Cutter, Elias S. Sotirchos, Kaarina Kowalec, Amber Salter, Shiv Saidha, Ellen M. Mowry, Peter A. Calabresi, Ruth Ann Marrie, Kathryn C. Fitzgerald
Publikováno v:
Neurology(R) neuroimmunologyneuroinflammation. 10(1)
Background and ObjectivesObservational studies suggest low levels of 25-hydroxyvitamin D (25[OH]D) may be associated with increased disease activity in people with multiple sclerosis (PwMS). Large-scale genome-wide association studies (GWAS) suggest