Výsledky vyhledávání - "Jerry M. Farley"

Akademický článek

Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease.

Autor: Samuel O Adeosun, Xu Hou, Yun Jiao, Baoying Zheng, Sherry Henry, Rosanne Hill, Zhi He, Amar Pani, Patrick Kyle, Xiaoming Ou, Thomas Mosley, Jerry M Farley, Craig Stockmeier, Ian Paul, Steven Bigler, Roberta Diaz Brinton, Richard Smeyne, Jun Ming Wang

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e50040 (2012)

Restorative/protective therapies to restore dopamine neurons in the substantia nigra pars compacta (SNpc) are greatly needed to effectively change the debilitating course of Parkinson's disease. In this study, we tested the therapeutic potential of a

Externí odkaz: https://doaj.org/article/59d821c9f03f4717ba7f657db3177b07

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Molecular Mechanisms of Renal Blood Flow Autoregulation

Autor: Jerry M. Farley, Mallikarjuna R. Pabbidi, Richard J. Roman, Marilyn Burke

Publikováno v: Current Vascular Pharmacology

Diabetes and hypertension are the leading causes of chronic kidney disease and their incidence is increasing at an alarming rate. Both are associated with impairments in the autoregulation of renal blood flow (RBF) and greater transmission of fluctua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292875e1114fa23f58b44b2a48d10e3d
https://doi.org/10.2174/15701611113116660149

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Akademický článek

Characterization of Contractile Function and Expression of Muscarinic Receptors, G Proteins and Adenylate Cyclase in Cultured Tracheal Smooth Muscle of Swine.

Autor: Jen-Tsung Hsieh, Courtney¹, Jerry M. Farley, Courtney¹ jfarley@pharmacology.umsmed.edu

Publikováno v: Journal of Biomedical Science. 2002, Vol. 9 Issue 4, p339-347. 9p. 1 Diagram, 2 Charts, 3 Graphs.

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Cardiac toxicity of some echinocandin antifungals

Autor: John D. Cleary, Kayla R. Stover, Patrick B. Kyle, Jerry M. Farley

Publikováno v: Expert Opinion on Drug Safety. 13:5-14

Unexplained cardiovascular decompensation has been observed during central venous administration of some echinocandins.The purpose of this study was to assess cardiac toxicity associated with the echinocandins.Isolated rat hearts (Langendorff model)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fb66a82dc7dd826f2df2a7ac8c0dd3
https://doi.org/10.1517/14740338.2013.829036

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Cardiac Toxicity of Azole Antifungals

Autor: Jon Hosler, Kayla R. Stover, Jerry M. Farley, John D. Cleary, Patrick B. Kyle, William Daley

Publikováno v: Pharmacology & Pharmacy. :362-368

Cardiac toxicity is an uncommon side effect of anti-fungal therapy. Until the recent reports of itraconazole (ITZ) associated cardiac failure, amphotericin was the antifungal most frequently reported with arrhythmias. We evaluated the cardiac effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcf163b086513a252443801e559949f9
https://doi.org/10.4236/pp.2013.43052

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Prostaglandin E2Enhances Acetylcholine-Induced, Ca2+-Dependent Ionic Currents in Swine Tracheal Mucous Gland Cells

Autor: Jerry M. Farley, Huiling Liu

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 322:501-513

Airway submucosal gland cell (SMGC) secretions are under the control of various neurotransmitters and hormones. Interactions between different pathways, such as those mediated by cAMP and Ca(2+), in controlling mucus or electrolyte secretions are not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f0dc7c3316a5d09fc78d52312f8e15
https://doi.org/10.1124/jpet.107.120154

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Tachyphylaxis to the inhibitory effect of L-type channel blockers on ACh-induced [Ca2+]i oscillations in porcine tracheal myocytes

Autor: Jerry M. Farley, Wen-Shuo Chung

Publikováno v: Journal of Biomedical Science. 14:129-143

Discrepancies about the role of L-type voltage-gated calcium channels (VGCC) in acetylcholine (ACh)-induced [Ca(2+)](i) oscillations in tracheal smooth muscle cells (TSMCs) have been seen in recent reports. We demonstrate here that ACh-induced [Ca(2+

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e2e7adb65e8a2772fb0cdcf2345faa
https://doi.org/10.1007/s11373-006-9122-6

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Prostanoids Secreted by Alveolar Macrophages Enhance Ionic Currents in Swine Tracheal Submucosal Gland Cells

Autor: Huiling Liu, Jerry M. Farley, Abulkhair M. Mamoon

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 315:729-739

We examined the effect of substances released by swine alveolar macrophages (AMs) on ionic currents in airway submucosal gland cells (SGCs). AMs obtained by lavage were activated by 24-h zymosan exposure (0.1 mg/ml). Supernatant was collected and use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6093603e031c59c9c92c5140dc1d77b3
https://doi.org/10.1124/jpet.105.088542

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Cardiodepressant and neurologic actions of Solenopsis invicta (imported fire ant) venom alkaloids

Autor: Jerry M. Farley, Jordan Butler, George E. Howell, Gene B. Yi, Richard D. deShazo, Huiling Liu, Anne B. Yates, Robin W. Rockhold, N.P.D. Nanayakkara

Publikováno v: Annals of Allergy, Asthma & Immunology. 94:380-386

Background We hypothesized that the alkaloid compounds that are the majority components of fire ant ( Solenopsis invicta ) venom are capable of producing cardiovascular and central nervous system toxic effects in mammals. Objective To evaluate toxic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8569eb1fb154c1abb8f021a8645352d9
https://doi.org/10.1016/s1081-1206(10)60991-x

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