Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jerry L. Perrard"'
Autor:
Jerry L. Perrard, Antu Kalathookunnel Antony, Huaizhu Wu, Christie M. Ballantyne, Zeqin Lian, Hua Liu, Lothar Hennighausen, Pradip K. Saha, Xiaoyuan Dai Perrard, Sean M. Hartig, Aaron R. Cox
Publikováno v:
Diabetes. 70:720-732
CD11c+ macrophages/dendritic cells (MDCs) are increased and display the classically activated M1-like phenotype in obese adipose tissue (AT) and may contribute to AT inflammation and insulin resistance. Stat1 is a key transcription factor for MDC pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34a113cdfca2066e68e9bfebea50127d
https://doi.org/10.2337/db20-0634
https://doi.org/10.2337/db20-0634
Autor:
Lothar Hennighausen, Zeqin Lian, Jerry L. Perrard, Antu Kalathookunnel Antony, Christie M. Ballantyne, Huaizhu Wu, Clifton W. Smith, Xiaoyuan Dai Perrard
Publikováno v:
Diabetes. 67
Background: Obesity is a global epidemic and major risk factor for insulin resistance and type 2 diabetes. Obesity is associated with low grade chronic inflammation of adipose tissue (AT). F4/80+CD11c+ macrophages/dendritic cells are increased and po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c54f958430aebaf9b0cdf39b0b614700
https://doi.org/10.2337/db18-2037-p
https://doi.org/10.2337/db18-2037-p
Autor:
Amir Mansoori, Christie M. Ballantyne, Jerry L. Perrard, Ilvira M. Khan, Huaizhu Wu, Xiao Yuan Dai Perrard, C. Wayne Smith
Publikováno v:
Atherosclerosis. 233:419-428
High-fat diet (HFD) feeding in mice is characterized by accumulation of αβ T cells in adipose tissue. However, the contribution of αβ T cells to obesity-induced inflammation of skeletal muscle, a major organ of glucose uptake, is unknown. This st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffd1c5f678e08d6f40e123ec1d75691
https://doi.org/10.1016/j.atherosclerosis.2014.01.011
https://doi.org/10.1016/j.atherosclerosis.2014.01.011
Autor:
Xiaoyuan Dai Perrard, Aparna Mukherjee, Yuguo Chen, Huaizhu Wu, Jerry L. Perrard, Corina Rosales, Henry J. Pownall, C. Wayne Smith, Jiali Wang, Christie M. Ballantyne
Publikováno v:
Atherosclerosis. 223:342-349
Objective To identify the role of triglyceride-rich lipoproteins (TGRLs) and apoE, a major apolipoprotein in TGRLs, in adipose tissue inflammation with high-fat diet (HFD)-induced obesity. Methods Male apoE −/− and C57BL/6J wild-type (WT) mice fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cdf2ffd84881900d51587828bfb8edd
https://doi.org/10.1016/j.atherosclerosis.2012.06.003
https://doi.org/10.1016/j.atherosclerosis.2012.06.003
Autor:
Qun Wang, Xiaoyuan Dai Perrard, Amir Mansoori, Christie M. Ballantyne, Huaizhu Wu, Ron C. Hoogeveen, Joe L. Raya, Jerry L. Perrard, C. Wayne Smith
Publikováno v:
Atherosclerosis. 219:100-108
We studied the effects of weight loss induced by either a low-fat normal diet (ND) or restriction of high-fat diet (HFD) on hepatic steatosis, inflammation in the liver and adipose tissue (AT), and blood monocytes of obese mice.In mice with HFD-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15cd4f4f82cccfce2b791efca4363a6
https://doi.org/10.1016/j.atherosclerosis.2011.07.025
https://doi.org/10.1016/j.atherosclerosis.2011.07.025
Autor:
Huaizhu Wu, Xiaoyuan Dai Perrard, C. Wayne Smith, Leif E. Peterson, John F. Sweeney, Sudip Ghosh, Jerry L. Perrard, Lawrence Chan, Lili Feng, Gabriela Garcia, Christie M. Ballantyne
Publikováno v:
Circulation. 115:1029-1038
Background— Obesity is associated with chronic inflammation, which includes increased macrophage accumulation in adipose tissue (AT) and upregulation of chemokines and cytokines. T cells also play important roles in chronic inflammatory diseases su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af509c7b00a3342a5d135e6d180f688d
https://doi.org/10.1161/circulationaha.106.638379
https://doi.org/10.1161/circulationaha.106.638379
Autor:
Ba-Bie Teng, Huaizhu Wu, Lu Xu, Xiaoyuan Dai Perrard, Xinhua Xiao, Scott I. Simon, Donglin Yang, Jerry L. Perrard, Christie M. Ballantyne
Objective— To examine infiltration of blood foamy monocytes, containing intracellular lipid droplets, into early atherosclerotic lesions and its contribution to development of nascent atherosclerosis. Approach and Results— In apoE –/– mice fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde8fe8d311b14c4f0bf6515e24a1c9f
https://europepmc.org/articles/PMC4514542/
https://europepmc.org/articles/PMC4514542/
Autor:
Merry L. Lindsey, Jerry L. Perrard, Leonardo H. Mendoza, Mark L. Entman, Alan R. Burns, C. Wayne Smith, Nikolaos G. Frangogiannis, Christie M. Ballantyne, Lloyd H. Michael
Publikováno v:
Circulation. 98:687-698
Background —Myocardial infarction is associated with an intense inflammatory reaction leading to healing and scar formation. Because mast cells are a significant source of fibrogenic factors, we investigated mast cell accumulation and regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4860d3afc5b372845884030ed8670d6
https://doi.org/10.1161/01.cir.98.7.687
https://doi.org/10.1161/01.cir.98.7.687
Autor:
Mark L. Entman, Liping Tang, C. W. Smith, Daniel C. Bullard, Arthur L. Beaudet, Christie M. Ballantyne, Huifang Lu, S B Shappell, Jerry L. Perrard
Publikováno v:
Journal of Clinical Investigation. 99:1340-1350
To better define the specific function of Mac-1 (CD11b) versus LFA-1 (CD11a) and the other CD11 integrins in vivo, we have disrupted murine CD11b by targeted homologous recombination in embryonic stem cells and generated mice which are homozygous for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbea3d2f0c7dc2f71421057c209c3e0b
https://doi.org/10.1172/jci119293
https://doi.org/10.1172/jci119293
Autor:
Ilvira M. Khan, Jerry L. Perrard, Donglin Yang, C. Wayne Smith, Xiaoyuan Dai Perrard, Huaizhu Wu, Erlie Jiang, Christie M. Ballantyne
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 34(1)
Objective— T cells, particularly CD8 + T cells, are major participants in obesity-linked adipose tissue (AT) inflammation. We examined the mechanisms of CD8 + T-cell accumulation and activation in AT and the role of CD11a, a β2 integrin. Approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f867e3c64d5a1da58c15b5255a4f24b3
https://pubmed.ncbi.nlm.nih.gov/24158516
https://pubmed.ncbi.nlm.nih.gov/24158516