Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jerry Krcek"'
Autor:
Thatchawan Thanasupawat, Aleksandra Glogowska, Maxwell Burg, Jerry Krcek, Jason Beiko, Marshall Pitz, Guo‐Jun Zhang, Sabine Hombach‐Klonisch, Thomas Klonisch
Publikováno v:
Molecular Oncology, Vol 12, Iss 9, Pp 1464-1479 (2018)
The C1q/TNF‐related peptide 8 (CTRP8) has recently emerged as a novel ligand of the G protein‐coupled receptor RXFP1 in the fatal brain tumor glioblastoma (GBM). We previously demonstrated that the CTRP8‐RXFP1 ligand–receptor system promotes
Externí odkaz:
https://doaj.org/article/7a29a0b669f74ce7882b02597f2aa12d
Autor:
Thatchawan Thanasupawat, Aleksandra Glogowska, Christopher Pascoe, Sai Nivedita Krishnan, Maliha Munir, Farhana Begum, Jason Beiko, Jerry Krcek, Marc R. Del Bigio, Marshall Pitz, Yaoqing Shen, Victor Spicer, Kevin M. Coombs, John Wilkins, Sabine Hombach-Klonisch, Thomas Klonisch
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9566 (2021)
Malignant gliomas derive from brain glial cells and represent >75% of primary brain tumors. This includes anaplastic astrocytoma (grade III; AS), the most common and fatal glioblastoma multiforme (grade IV; GBM), and oligodendroglioma (ODG). We have
Externí odkaz:
https://doaj.org/article/08c2bbdee2e24676a1e73b8bb5f49f7a
Publikováno v:
Interdisciplinary Neurosurgery, Vol 9, Iss , Pp 30-33 (2017)
Unlike non-Hodgkin's lymphoma, central nervous system involvement with classical Hodgkin's lymphoma is exceedingly rare, thus information regarding treatment and prognostication of the disease is lacking. We present the case of a 47 year old female w
Externí odkaz:
https://doaj.org/article/24da9f445799418cb2e8d9ac18506290
Autor:
Marc R. Del Bigio, Yaoqing Shen, Aleksandra Glogowska, Farhana Begum, John A. Wilkins, Thomas Klonisch, Kevin M. Coombs, Christopher D. Pascoe, Jason Beiko, Marshall Pitz, Jerry Krcek, Victor Spicer, Maliha Munir, Thatchawan Thanasupawat, Sabine Hombach-Klonisch, Sai Nivedita Krishnan
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9566, p 9566 (2021)
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9566, p 9566 (2021)
Volume 22
Issue 17
Malignant gliomas derive from brain glial cells and represent >
75% of primary brain tumors. This includes anaplastic astrocytoma (grade III
AS), the most common and fatal glioblastoma multiforme (grade IV
GBM), and oligodendroglioma
75% of primary brain tumors. This includes anaplastic astrocytoma (grade III
AS), the most common and fatal glioblastoma multiforme (grade IV
GBM), and oligodendroglioma
Autor:
Thomas Klonisch, Thatchawan Thanasupawat, Maxwell Burg, Sabine Hombach-Klonisch, Jerry Krcek, Jason Beiko, Aleksandra Glogowska, Marshall Pitz, Guo-Jun Zhang
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 12, Iss 9, Pp 1464-1479 (2018)
Molecular Oncology, Vol 12, Iss 9, Pp 1464-1479 (2018)
The C1q/TNF-related peptide 8 (CTRP8) has recently emerged as a novel ligand of the G protein-coupled receptor RXFP1 in the fatal brain tumor glioblastoma (GBM). We previously demonstrated that the CTRP8-RXFP1 ligand-receptor system promotes motility
Publikováno v:
Interdisciplinary Neurosurgery, Vol 9, Iss, Pp 30-33 (2017)
Unlike non-Hodgkin's lymphoma, central nervous system involvement with classical Hodgkin's lymphoma is exceedingly rare, thus information regarding treatment and prognostication of the disease is lacking. We present the case of a 47 year old female w
Autor:
Thomas Klonisch, Inder M. Verma, Aleksandra Glogowska, Jerry Krcek, Jason Beiko, Sherry Krawitz, Sabine Hombach-Klonisch, Saeid Ghavami, Hugo Bergen, Thatchawan Thanasupawat, Suchitra Natarajan, Marshall Pitz, Amy Rommel
Publikováno v:
Molecular Oncology
The multikinase inhibitor and FDA-approved drug dovitinib (Dov) crosses the blood-brain barrier and was recently used as single drug application in clinical trials for GB patients with recurrent disease. The Dov-mediated molecular mechanisms in GB ce
Autor:
Appalaraju Jaggupilli, Aleksandra Glogowska, G. William Wong, Jerry Krcek, Thomas Klonisch, Prashen Chelikani, Maxwell Burg, Marshall Pitz, Sabine Hombach-Klonisch, Thatchawan Thanasupawat
Publikováno v:
British Journal of Pharmacology. 174:1025-1033
We established the role of the GPCR relaxin/insulin-like family peptide receptor 1 (RXFP1 receptor) as a novel active receptor in human glioblastoma (GB), a fatal brain tumour. We identified C1q/TNF-related protein 8 (CTRP8) as a novel agonist of the
Autor:
Frederick A. Zeiler, Jerry Krcek
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 39:117-120
Autor:
Jason Beiko, Aleksandra Glogowska, Thatchawan Thanasupawat, Sabine Hombach-Klonisch, M. Burg, Thomas Klonisch, Marshall Pitz, Jerry Krcek
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 43:S15-S16
We identified the G protein coupled relaxin receptor RXFP1 in glioblastoma (GB) and discovered C1q-tumor necrosis factor related protein 8 (CTRP8) as a novel ligand of RXFP1 in this common and most aggressive form of brain tumor. The known RXFP1 liga