Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jerry J. Gipp"'
Autor:
Christopher J. Loftus, Chad M. Vezina, Wade Bushman, Letitia Wong, Vatsal Mehta, Jerry J. Gipp, Jason Carr, Sanghee Lee, Molly Benck
Publikováno v:
The Prostate. 74:346-358
BACKGROUND Prostatic inflammation is an important factor in development and progression of BPH/LUTS. This study was performed to characterize the normal development and vascular anatomy of the mouse prostate and then examine, for the first time, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::253a7b98bc8981465c4f6dbf47cd8e26
https://doi.org/10.1002/pros.22751
https://doi.org/10.1002/pros.22751
Publikováno v:
Differentiation. 79:41-47
Stromal-epithelial signaling is a critical regulator of normal prostate development and has been speculated to play an equally important role in the development and progression of prostate cancer. Sonic hedgehog (Shh) and bone morphogenetic proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c5944da90aa42ff30c0087fea0a6a3
https://doi.org/10.1016/j.diff.2009.08.009
https://doi.org/10.1016/j.diff.2009.08.009
Publikováno v:
Oncogene
Nature Precedings
Nature Precedings
The Hedgehog (Hh) pathway contributes to prostate cancer growth and progression. The presence of robust Sonic Hedgehog (Shh) expression in both normal prostate and localized cancer challenged us to explain the unique growth-promoting effect in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e0ef2fc24964c279d516c7bf3e3ed7
http://europepmc.org/articles/PMC2795794
http://europepmc.org/articles/PMC2795794
Publikováno v:
Journal of Urology. 177:1179-1185
Several recent reports highlighted the role of hedgehog signaling in prostate cancer. However, the relative contributions of autocrine and paracrine hedgehog signaling to tumor growth and progression are unclear. Efforts to model autocrine signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379e1257ffeb04ff99768275badd12dc
https://doi.org/10.1016/j.juro.2006.10.032
https://doi.org/10.1016/j.juro.2006.10.032
Publikováno v:
Journal of Biological Chemistry. 277:30730-30737
Constitutive and inducible expression of the gene encoding the modulator subunit of human glutamate-cysteine ligase (GCLM) is regulated by either of two regions of the promoter; an antioxidant response element (ARE) at −302:−291 and a 44-bp fragm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f823383587c8bc7c4ab92740feb451fb
https://doi.org/10.1074/jbc.m205225200
https://doi.org/10.1074/jbc.m205225200
Publikováno v:
Journal of Urology. 191
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f5ba2be8cea2777fdc408644f89aaf4
https://doi.org/10.1016/j.juro.2014.02.716
https://doi.org/10.1016/j.juro.2014.02.716
Publikováno v:
Journal of Diabetes Research, Vol 2014 (2014)
Journal of Diabetes Research
Journal of Diabetes Research
A higher incidence of lower urinary tract symptoms (LUTS) among diabetic men is unexplained. Recently, prostate inflammation and fibrosis have been implicated as major contributing factors to bladder outlet obstruction and LUTS. We characterized the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8825a06fda09e246fdf7bf89b550be
https://doaj.org/article/2e027efaa1de4670b4f71f1127f705df
https://doaj.org/article/2e027efaa1de4670b4f71f1127f705df
Publikováno v:
Biochemical Journal. 332:373-381
gamma-Glutamylcysteine synthetase (GCS), the rate-limiting enzyme in the de novo synthesis of GSH, is a heterodimer, consisting of a catalytic (GCSh) and a regulatory subunit (GCSl). We previously demonstrated that the constitutive and beta-naphthofl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7746b09612ff61da8a0cd9dce63c6bad
https://doi.org/10.1042/bj3320373
https://doi.org/10.1042/bj3320373
Publikováno v:
Journal of Biological Chemistry. 272:7445-7454
Glutathione (GSH) is an abundant cellular non-protein sulfhydryl that functions as an important protectant against reactive oxygen species and electrophiles, is involved in the detoxification of xenobiotics, and contributes to the maintenance of cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e2e28377a90b63440646c08bb596cb
https://doi.org/10.1074/jbc.272.11.7445
https://doi.org/10.1074/jbc.272.11.7445
Publikováno v:
Biochemical and Biophysical Research Communications. 206:584-589
We have cloned and sequenced a full length cDNA for the light subunit of human liver γ-glutamylcysteine synthetase (GCS1). The GCS1 cDNA consists of 1628 bp, containing an open reading frame of 822 bp which encodes a protein of 274 amino acids havin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313eff19ed8e464d19776f4bff4dcf96
https://doi.org/10.1006/bbrc.1995.1083
https://doi.org/10.1006/bbrc.1995.1083