Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jerry G. Webb"'
Autor:
Jerry G. Webb
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 27:539-543
The kallikrein/kinin system uses two distinct serine proteases, plasma kallikrein and tissue kallikrein, to yield bradykinin and Lys-bradykinin (kallidin) from specific substrate kininogens. The kallikrein/kinin system is known to have a role in cont
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 22:310-316
The aim of this study was to investigate the effects of bradykinin on conventional outflow facility in relation to kinin effects on matrix metalloproteinase (MMP) secretion. Conventional outflow facility was measured in isolated bovine segments perfu
Publikováno v:
The American Surgeon. 72:51-54
Migration and proliferation of vascular smooth muscle cells (VSMCs) are two events involved in atherosclerosis, restenosis after balloon angioplasty, and stenosis of grafted vessels. Platelet-derived growth factor (PDGF) found in stenotic vessels is
Publikováno v:
The American Surgeon. 69:131-135
Aprotinin has been reported to reduce plasma levels of inflammatory cytokines associated with cardiopulmonary bypass (CPB). Because CPB is also associated with elevated levels of bacterial lipopolysaccharide (LPS) and LPS stimulates release of inflam
Publikováno v:
Critical Care Medicine. 28:3593-3598
OBJECTIVES: Beta-adrenergic receptor agonists such as isoproterenol inhibit production of tumor necrosis factor (TNF)-alpha in a number of cell types. Because the heart is a source of TNF-alpha, we hypothesized that isoproterenol would inhibit cardia
Autor:
Kenneth R. Smart, Debra J. Warejcka, Manuel R. Castresana, Martin L. Dalton, Jerry G. Webb, Walter H. Newman
Publikováno v:
The American Surgeon. 66:947-951
Recent evidence suggests that inflammatory cytokines, particularly tumor necrosis factor a (TNF-α), may play a role in heart disease. Elevated plasma levels of the cytokine have been reported in congestive heart failure and severe angina and after m
Publikováno v:
Experimental eye research. 92(6)
Bradykinin stimulation of B(2) kinin receptors has been shown to promote matrix metallo-proteinase (MMP) secretion from trabecular meshwork cells and to increase conventional outflow facility. Because acute secretion of MMPs can be dependent on the a
Autor:
Steven W. Kubalak, Jerry G. Webb
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 264:H86-H96
The mechanism by which angiotensin II (ANG II) potentiates hormone-induced adenosine 3',5'-cyclic monophosphate (cAMP) formation was studied in cultured rat vascular smooth muscle cells. Incubation of cells for 60 s with 100 nM ANG II produced a two-
Publikováno v:
Journal of receptor and signal transduction research. 30(2)
Although bradykinin (BK) and insulin like growth factor-1 (IGF-1) have been shown to modulate the functional and structural integrity of the arterial wall, the cellular mechanisms through which this regulation occurs is still undefined. The present s
Publikováno v:
Journal of Molecular and Cellular Cardiology. 23:199-205
Cyclic AMP regulation by muscarinic and adenosine receptors was investigated in isolated canine ventricular myocytes. Both the muscarinic receptor agonist, carbachol, and the adenosine receptor agonist, phenylisopropyladenosine, decreased isoproteren