Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Jerry Eichler"'
Autor:
Shahar Sofer, Zlata Vershinin, Leen Mashni, Ran Zalk, Anat Shahar, Jerry Eichler, Iris Grossman-Haham
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The swimming device of archaea—the archaellum—presents asparagine (N)-linked glycans. While N-glycosylation serves numerous roles in archaea, including enabling their survival in extreme environments, how this post-translational modifica
Externí odkaz:
https://doaj.org/article/e21d45cd85f745c8a891faf697ba47e0
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109108- (2024)
Summary: Many bacterial pathogens employ the type III secretion system (T3SS), a specialized complex that transports effector proteins that manipulate various cellular processes. The T3SS forms a translocon pore within the host-cell membrane consisti
Externí odkaz:
https://doaj.org/article/93be1dfcacb445ee8d94236323479bfc
Publikováno v:
BBA Advances, Vol 6, Iss , Pp 100120- (2024)
While performed by all three domains of life, N-glycosylation in Archaea is less well described than are the parallel eukaryal and bacterial processes. Still, what is known of the archaeal version of this universal post-translational modification rev
Externí odkaz:
https://doaj.org/article/04e4225ab0a44f68a6ecd7a261dcb41a
Publikováno v:
Entropy, Vol 25, Iss 9, p 1351 (2023)
In recent years, it has become clear that intrinsically disordered protein segments play diverse functional roles in many cellular processes, thus leading to a reassessment of the classical structure–function paradigm. One class of intrinsically di
Externí odkaz:
https://doaj.org/article/4997122b34374199b5f7a4bc5f6e17f0
Autor:
L. Johanna Gebhard, Zlata Vershinin, Tomás Alarcón-Schumacher, Jerry Eichler, Susanne Erdmann
Publikováno v:
Viruses, Vol 15, Iss 7, p 1469 (2023)
N-glycosylation is a post-translational modification of proteins that occurs across all three domains of life. In Archaea, N-glycosylation is crucial for cell stability and motility, but importantly also has significant implications for virus–host
Externí odkaz:
https://doaj.org/article/79f43c070feb4ab2808bf387e67ee508
Autor:
Yonatan Chemla, Michael Peeri, Mathias Luidor Heltberg, Jerry Eichler, Mogens Høgh Jensen, Tamir Tuller, Lital Alfonta
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The mechanisms for regulating translation re-initiation in bacteria remain poorly understood. Here, the authors screened a library of synthetic operons and identified a ribosome termination structure that modulates re-initiation efficiency and which
Externí odkaz:
https://doaj.org/article/f945cec54ed844a3bf6360085372dfe1
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Whereas N-glycosylation is a seemingly universal process in Archaea, pathways of N-glycosylation have only been experimentally verified in a mere handful of species. Toward expanding the number of delineated archaeal N-glycosylation pathways, the inv
Externí odkaz:
https://doaj.org/article/47975201b00846939495c1dd0e7a458c
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109428- (2021)
Summary: In an event reminiscent of eukaryotic ubiquitination, the bacterial prokaryotic ubiquitin-like protein (Pup)-proteasome system (PPS) marks target proteins for proteasomal degradation by covalently attaching Pup, the bacterial tagging molecul
Externí odkaz:
https://doaj.org/article/321aa819f64f48e6909f98642fd7f80f
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Halobacterium salinarum are halophilic archaea that display directional swimming in response to various environmental signals, including light, chemicals and oxygen. In Hbt. salinarum, the building blocks (archaellins) of the archaeal swimming appara
Externí odkaz:
https://doaj.org/article/d342a1d1201549a588c899bf2ec71c1a
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
N-glycosylation is a post-translational modification that occurs in all three domains. In Archaea, however, N-linked glycans present a degree of compositional diversity not observed in either Eukarya or Bacteria. As such, it is surprising that nonulo
Externí odkaz:
https://doaj.org/article/6dc53a9acfb5435fbb72096da28a6433